| Full name: elongation factor 1 homolog | Alias Symbol: MGC4549|ELF1 | ||
| Type: protein-coding gene | Cytoband: 19p13.2 | ||
| Entrez ID: 84337 | HGNC ID: HGNC:28691 | Ensembl Gene: ENSG00000130165 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ELOF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ELOF1 | 84337 | 225156_at | 0.3409 | 0.4813 | |
| GSE26886 | ELOF1 | 84337 | 225156_at | -0.4658 | 0.0318 | |
| GSE45670 | ELOF1 | 84337 | 225156_at | 0.3962 | 0.0009 | |
| GSE53622 | ELOF1 | 84337 | 173732 | 0.1605 | 0.0178 | |
| GSE53624 | ELOF1 | 84337 | 173732 | 0.2508 | 0.0078 | |
| GSE63941 | ELOF1 | 84337 | 225156_at | 0.3038 | 0.4305 | |
| GSE77861 | ELOF1 | 84337 | 225156_at | 0.4487 | 0.0151 | |
| GSE97050 | ELOF1 | 84337 | A_23_P130689 | 0.2772 | 0.2401 | |
| SRP007169 | ELOF1 | 84337 | RNAseq | 0.7464 | 0.1716 | |
| SRP008496 | ELOF1 | 84337 | RNAseq | 1.0825 | 0.0089 | |
| SRP064894 | ELOF1 | 84337 | RNAseq | 0.7129 | 0.0407 | |
| SRP133303 | ELOF1 | 84337 | RNAseq | 0.2773 | 0.0378 | |
| SRP159526 | ELOF1 | 84337 | RNAseq | 0.2889 | 0.2429 | |
| SRP193095 | ELOF1 | 84337 | RNAseq | 0.0664 | 0.5748 | |
| SRP219564 | ELOF1 | 84337 | RNAseq | 0.6565 | 0.0558 | |
| TCGA | ELOF1 | 84337 | RNAseq | 0.0646 | 0.2550 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ELOF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ELOF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ELOF1 | 84337 | 4 | 2 | 24 | |
| GSE20123 | ELOF1 | 84337 | 3 | 1 | 26 | |
| GSE43470 | ELOF1 | 84337 | 2 | 6 | 35 | |
| GSE46452 | ELOF1 | 84337 | 47 | 1 | 11 | |
| GSE47630 | ELOF1 | 84337 | 4 | 7 | 29 | |
| GSE54993 | ELOF1 | 84337 | 16 | 3 | 51 | |
| GSE54994 | ELOF1 | 84337 | 6 | 13 | 34 | |
| GSE60625 | ELOF1 | 84337 | 9 | 0 | 2 | |
| GSE74703 | ELOF1 | 84337 | 2 | 4 | 30 | |
| GSE74704 | ELOF1 | 84337 | 0 | 1 | 19 | |
| TCGA | ELOF1 | 84337 | 16 | 12 | 68 |
Total number of gains: 109; Total number of losses: 50; Total Number of normals: 329.
Somatic mutations of ELOF1:
Generating mutation plots.
Highly correlated genes for ELOF1:
Showing top 20/896 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ELOF1 | THADA | 0.845238 | 3 | 0 | 3 |
| ELOF1 | SLC25A14 | 0.830234 | 3 | 0 | 3 |
| ELOF1 | SCAF4 | 0.823319 | 3 | 0 | 3 |
| ELOF1 | HNRNPC | 0.818996 | 3 | 0 | 3 |
| ELOF1 | ZNF766 | 0.818271 | 3 | 0 | 3 |
| ELOF1 | SNRPD3 | 0.812051 | 3 | 0 | 3 |
| ELOF1 | NACC1 | 0.809132 | 5 | 0 | 5 |
| ELOF1 | GDAP1 | 0.79243 | 3 | 0 | 3 |
| ELOF1 | RAD18 | 0.78873 | 3 | 0 | 3 |
| ELOF1 | TAF11 | 0.78812 | 3 | 0 | 3 |
| ELOF1 | AAK1 | 0.786659 | 3 | 0 | 3 |
| ELOF1 | TUBA1B | 0.786238 | 4 | 0 | 4 |
| ELOF1 | DERL1 | 0.781766 | 3 | 0 | 3 |
| ELOF1 | MSH6 | 0.780463 | 3 | 0 | 3 |
| ELOF1 | TBC1D16 | 0.778346 | 3 | 0 | 3 |
| ELOF1 | ZBED4 | 0.778212 | 3 | 0 | 3 |
| ELOF1 | C9orf78 | 0.778031 | 3 | 0 | 3 |
| ELOF1 | FXR1 | 0.776952 | 3 | 0 | 3 |
| ELOF1 | POLA1 | 0.775288 | 3 | 0 | 3 |
| ELOF1 | MRPL35 | 0.774581 | 3 | 0 | 3 |
For details and further investigation, click here
