| Full name: zinc finger protein 121 | Alias Symbol: ZHC32|ZNF20 | ||
| Type: protein-coding gene | Cytoband: 19p13.2 | ||
| Entrez ID: 7675 | HGNC ID: HGNC:12904 | Ensembl Gene: ENSG00000197961 | OMIM ID: 194628 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF121:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF121 | 7675 | 1553979_at | 0.6707 | 0.3423 | |
| GSE26886 | ZNF121 | 7675 | 1553979_at | 0.8094 | 0.0013 | |
| GSE45670 | ZNF121 | 7675 | 1553979_at | 0.3968 | 0.0023 | |
| GSE53622 | ZNF121 | 7675 | 3383 | -0.1281 | 0.3892 | |
| GSE53624 | ZNF121 | 7675 | 65288 | 0.1603 | 0.0061 | |
| GSE63941 | ZNF121 | 7675 | 1553979_at | 0.0659 | 0.9236 | |
| GSE77861 | ZNF121 | 7675 | 1553979_at | 0.4322 | 0.0954 | |
| GSE97050 | ZNF121 | 7675 | A_24_P935782 | -0.0357 | 0.9369 | |
| SRP007169 | ZNF121 | 7675 | RNAseq | -0.0563 | 0.8900 | |
| SRP008496 | ZNF121 | 7675 | RNAseq | -0.0043 | 0.9839 | |
| SRP064894 | ZNF121 | 7675 | RNAseq | -0.1888 | 0.3372 | |
| SRP133303 | ZNF121 | 7675 | RNAseq | 0.0979 | 0.4558 | |
| SRP159526 | ZNF121 | 7675 | RNAseq | 0.1130 | 0.7478 | |
| SRP193095 | ZNF121 | 7675 | RNAseq | -0.0813 | 0.3164 | |
| SRP219564 | ZNF121 | 7675 | RNAseq | 0.4307 | 0.3445 | |
| TCGA | ZNF121 | 7675 | RNAseq | 0.0888 | 0.2778 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNF121 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF121:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF121 | 7675 | 4 | 2 | 24 | |
| GSE20123 | ZNF121 | 7675 | 3 | 1 | 26 | |
| GSE43470 | ZNF121 | 7675 | 3 | 6 | 34 | |
| GSE46452 | ZNF121 | 7675 | 47 | 1 | 11 | |
| GSE47630 | ZNF121 | 7675 | 5 | 7 | 28 | |
| GSE54993 | ZNF121 | 7675 | 16 | 3 | 51 | |
| GSE54994 | ZNF121 | 7675 | 6 | 14 | 33 | |
| GSE60625 | ZNF121 | 7675 | 9 | 0 | 2 | |
| GSE74703 | ZNF121 | 7675 | 3 | 4 | 29 | |
| GSE74704 | ZNF121 | 7675 | 0 | 1 | 19 | |
| TCGA | ZNF121 | 7675 | 10 | 19 | 67 |
Total number of gains: 106; Total number of losses: 58; Total Number of normals: 324.
Somatic mutations of ZNF121:
Generating mutation plots.
Highly correlated genes for ZNF121:
Showing top 20/944 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF121 | ZNF766 | 0.868396 | 3 | 0 | 3 |
| ZNF121 | ZNF700 | 0.862589 | 3 | 0 | 3 |
| ZNF121 | ADAM10 | 0.855151 | 3 | 0 | 3 |
| ZNF121 | RBM26 | 0.851177 | 3 | 0 | 3 |
| ZNF121 | NUDT19 | 0.849059 | 3 | 0 | 3 |
| ZNF121 | TAF11 | 0.843862 | 3 | 0 | 3 |
| ZNF121 | RASA2 | 0.833331 | 3 | 0 | 3 |
| ZNF121 | EXOSC10 | 0.830819 | 3 | 0 | 3 |
| ZNF121 | NAP1L1 | 0.825929 | 3 | 0 | 3 |
| ZNF121 | MDN1 | 0.822839 | 3 | 0 | 3 |
| ZNF121 | MRPS30 | 0.809179 | 3 | 0 | 3 |
| ZNF121 | XRCC1 | 0.805594 | 3 | 0 | 3 |
| ZNF121 | TUBGCP3 | 0.797187 | 3 | 0 | 3 |
| ZNF121 | GUSB | 0.79616 | 3 | 0 | 3 |
| ZNF121 | ANKRD17 | 0.791647 | 3 | 0 | 3 |
| ZNF121 | LRRC47 | 0.791345 | 3 | 0 | 3 |
| ZNF121 | SEC22A | 0.789356 | 3 | 0 | 3 |
| ZNF121 | PHTF2 | 0.78934 | 3 | 0 | 3 |
| ZNF121 | MEA1 | 0.788023 | 3 | 0 | 3 |
| ZNF121 | PPHLN1 | 0.78799 | 3 | 0 | 3 |
For details and further investigation, click here
