| Full name: ankyrin repeat domain 28 | Alias Symbol: KIAA0379|PITK|PP6-ARS-A|PPP1R65 | ||
| Type: protein-coding gene | Cytoband: 3p25.1 | ||
| Entrez ID: 23243 | HGNC ID: HGNC:29024 | Ensembl Gene: ENSG00000206560 | OMIM ID: 611122 |
| Drug and gene relationship at DGIdb | |||
Expression of ANKRD28:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANKRD28 | 23243 | 226025_at | 0.0346 | 0.9599 | |
| GSE20347 | ANKRD28 | 23243 | 213035_at | -0.3031 | 0.0891 | |
| GSE23400 | ANKRD28 | 23243 | 213035_at | -0.0738 | 0.1306 | |
| GSE26886 | ANKRD28 | 23243 | 226025_at | -0.4646 | 0.0318 | |
| GSE29001 | ANKRD28 | 23243 | 213035_at | -0.3534 | 0.1744 | |
| GSE38129 | ANKRD28 | 23243 | 213035_at | -0.2959 | 0.0168 | |
| GSE45670 | ANKRD28 | 23243 | 226025_at | -0.3447 | 0.0062 | |
| GSE53622 | ANKRD28 | 23243 | 102520 | -0.3950 | 0.0000 | |
| GSE53624 | ANKRD28 | 23243 | 57329 | -0.2584 | 0.0002 | |
| GSE63941 | ANKRD28 | 23243 | 226025_at | -1.1288 | 0.0401 | |
| GSE77861 | ANKRD28 | 23243 | 226025_at | -0.3479 | 0.2558 | |
| GSE97050 | ANKRD28 | 23243 | A_24_P217365 | -0.2803 | 0.3077 | |
| SRP007169 | ANKRD28 | 23243 | RNAseq | -0.8759 | 0.0130 | |
| SRP008496 | ANKRD28 | 23243 | RNAseq | -0.5882 | 0.0040 | |
| SRP064894 | ANKRD28 | 23243 | RNAseq | -0.0328 | 0.9105 | |
| SRP133303 | ANKRD28 | 23243 | RNAseq | -0.1603 | 0.5162 | |
| SRP159526 | ANKRD28 | 23243 | RNAseq | -0.3821 | 0.2298 | |
| SRP193095 | ANKRD28 | 23243 | RNAseq | -0.0908 | 0.3952 | |
| SRP219564 | ANKRD28 | 23243 | RNAseq | 0.0363 | 0.9111 | |
| TCGA | ANKRD28 | 23243 | RNAseq | -0.2436 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ANKRD28 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ANKRD28:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANKRD28 | 23243 | 2 | 19 | 9 | |
| GSE20123 | ANKRD28 | 23243 | 2 | 19 | 9 | |
| GSE43470 | ANKRD28 | 23243 | 0 | 20 | 23 | |
| GSE46452 | ANKRD28 | 23243 | 2 | 17 | 40 | |
| GSE47630 | ANKRD28 | 23243 | 2 | 23 | 15 | |
| GSE54993 | ANKRD28 | 23243 | 6 | 1 | 63 | |
| GSE54994 | ANKRD28 | 23243 | 1 | 32 | 20 | |
| GSE60625 | ANKRD28 | 23243 | 5 | 0 | 6 | |
| GSE74703 | ANKRD28 | 23243 | 0 | 17 | 19 | |
| GSE74704 | ANKRD28 | 23243 | 1 | 13 | 6 | |
| TCGA | ANKRD28 | 23243 | 2 | 68 | 26 |
Total number of gains: 23; Total number of losses: 229; Total Number of normals: 236.
Somatic mutations of ANKRD28:
Generating mutation plots.
Highly correlated genes for ANKRD28:
Showing top 20/582 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANKRD28 | MRPS18B | 0.794339 | 3 | 0 | 3 |
| ANKRD28 | TAF9B | 0.789258 | 3 | 0 | 3 |
| ANKRD28 | MIER3 | 0.775363 | 3 | 0 | 3 |
| ANKRD28 | NAA30 | 0.774062 | 3 | 0 | 3 |
| ANKRD28 | RBM7 | 0.768385 | 3 | 0 | 3 |
| ANKRD28 | ZNF700 | 0.745173 | 3 | 0 | 3 |
| ANKRD28 | MLLT10 | 0.741304 | 3 | 0 | 3 |
| ANKRD28 | HIC2 | 0.740939 | 3 | 0 | 3 |
| ANKRD28 | ZNF268 | 0.740307 | 3 | 0 | 3 |
| ANKRD28 | PIGM | 0.735463 | 3 | 0 | 3 |
| ANKRD28 | VPS41 | 0.725321 | 3 | 0 | 3 |
| ANKRD28 | ABHD16A | 0.724283 | 3 | 0 | 3 |
| ANKRD28 | EIF2B1 | 0.721664 | 3 | 0 | 3 |
| ANKRD28 | METAP1 | 0.720727 | 3 | 0 | 3 |
| ANKRD28 | TAF11 | 0.719793 | 3 | 0 | 3 |
| ANKRD28 | HMGN1 | 0.713442 | 4 | 0 | 4 |
| ANKRD28 | FBXW2 | 0.711501 | 3 | 0 | 3 |
| ANKRD28 | LYSMD3 | 0.71144 | 4 | 0 | 3 |
| ANKRD28 | COIL | 0.708832 | 3 | 0 | 3 |
| ANKRD28 | FRMD6 | 0.705243 | 3 | 0 | 3 |
For details and further investigation, click here
