| Full name: TBC1 domain family member 10B | Alias Symbol: DKFZP434P1750|Rab27A-GAPbeta|FLJ13130|EPI64B | ||
| Type: protein-coding gene | Cytoband: 16p11.2 | ||
| Entrez ID: 26000 | HGNC ID: HGNC:24510 | Ensembl Gene: ENSG00000169221 | OMIM ID: 613620 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of TBC1D10B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TBC1D10B | 26000 | 220947_s_at | 0.4350 | 0.3749 | |
| GSE20347 | TBC1D10B | 26000 | 220947_s_at | 0.1266 | 0.1441 | |
| GSE23400 | TBC1D10B | 26000 | 220947_s_at | 0.2866 | 0.0000 | |
| GSE26886 | TBC1D10B | 26000 | 220947_s_at | -0.0376 | 0.8278 | |
| GSE29001 | TBC1D10B | 26000 | 220947_s_at | 0.1076 | 0.7706 | |
| GSE38129 | TBC1D10B | 26000 | 220947_s_at | 0.2387 | 0.0051 | |
| GSE45670 | TBC1D10B | 26000 | 220947_s_at | 0.3406 | 0.0021 | |
| GSE53622 | TBC1D10B | 26000 | 81207 | 0.3223 | 0.0000 | |
| GSE53624 | TBC1D10B | 26000 | 81207 | 0.4022 | 0.0000 | |
| GSE63941 | TBC1D10B | 26000 | 220947_s_at | 0.4086 | 0.1169 | |
| GSE77861 | TBC1D10B | 26000 | 220947_s_at | 0.1235 | 0.6363 | |
| GSE97050 | TBC1D10B | 26000 | A_33_P3219197 | 0.2180 | 0.3480 | |
| SRP007169 | TBC1D10B | 26000 | RNAseq | -0.1955 | 0.5901 | |
| SRP008496 | TBC1D10B | 26000 | RNAseq | -0.4629 | 0.0386 | |
| SRP064894 | TBC1D10B | 26000 | RNAseq | 0.5991 | 0.0016 | |
| SRP133303 | TBC1D10B | 26000 | RNAseq | 0.4215 | 0.0250 | |
| SRP159526 | TBC1D10B | 26000 | RNAseq | 0.3641 | 0.1549 | |
| SRP193095 | TBC1D10B | 26000 | RNAseq | 0.3151 | 0.0075 | |
| SRP219564 | TBC1D10B | 26000 | RNAseq | 0.4277 | 0.1122 | |
| TCGA | TBC1D10B | 26000 | RNAseq | 0.1293 | 0.0057 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TBC1D10B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TBC1D10B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TBC1D10B | 26000 | 5 | 5 | 20 | |
| GSE20123 | TBC1D10B | 26000 | 5 | 4 | 21 | |
| GSE43470 | TBC1D10B | 26000 | 3 | 3 | 37 | |
| GSE46452 | TBC1D10B | 26000 | 38 | 1 | 20 | |
| GSE47630 | TBC1D10B | 26000 | 11 | 7 | 22 | |
| GSE54993 | TBC1D10B | 26000 | 2 | 5 | 63 | |
| GSE54994 | TBC1D10B | 26000 | 5 | 9 | 39 | |
| GSE60625 | TBC1D10B | 26000 | 4 | 0 | 7 | |
| GSE74703 | TBC1D10B | 26000 | 3 | 2 | 31 | |
| GSE74704 | TBC1D10B | 26000 | 3 | 2 | 15 | |
| TCGA | TBC1D10B | 26000 | 20 | 10 | 66 |
Total number of gains: 99; Total number of losses: 48; Total Number of normals: 341.
Somatic mutations of TBC1D10B:
Generating mutation plots.
Highly correlated genes for TBC1D10B:
Showing top 20/457 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TBC1D10B | MS4A18 | 0.799375 | 3 | 0 | 3 |
| TBC1D10B | NTNG2 | 0.789363 | 3 | 0 | 3 |
| TBC1D10B | GPR182 | 0.763117 | 3 | 0 | 3 |
| TBC1D10B | MRGPRG | 0.759404 | 3 | 0 | 3 |
| TBC1D10B | ZNF48 | 0.75813 | 3 | 0 | 3 |
| TBC1D10B | GPR32 | 0.754133 | 3 | 0 | 3 |
| TBC1D10B | NMRAL1 | 0.753661 | 3 | 0 | 3 |
| TBC1D10B | C19orf44 | 0.752365 | 3 | 0 | 3 |
| TBC1D10B | DCDC1 | 0.751837 | 3 | 0 | 3 |
| TBC1D10B | STRC | 0.750506 | 3 | 0 | 3 |
| TBC1D10B | C9orf153 | 0.749465 | 3 | 0 | 3 |
| TBC1D10B | TMEM105 | 0.743267 | 3 | 0 | 3 |
| TBC1D10B | MAMLD1 | 0.740636 | 3 | 0 | 3 |
| TBC1D10B | DEFB121 | 0.740498 | 4 | 0 | 4 |
| TBC1D10B | OR2A5 | 0.737497 | 3 | 0 | 3 |
| TBC1D10B | TMUB1 | 0.736643 | 5 | 0 | 4 |
| TBC1D10B | C2CD4D | 0.730791 | 3 | 0 | 3 |
| TBC1D10B | GHSR | 0.727701 | 4 | 0 | 4 |
| TBC1D10B | TTLL9 | 0.720554 | 3 | 0 | 3 |
| TBC1D10B | CDKL4 | 0.718173 | 3 | 0 | 3 |
For details and further investigation, click here
