| Full name: transmembrane and ubiquitin like domain containing 1 | Alias Symbol: SB144 | ||
| Type: protein-coding gene | Cytoband: 7q36.1 | ||
| Entrez ID: 83590 | HGNC ID: HGNC:21709 | Ensembl Gene: ENSG00000164897 | OMIM ID: 614792 |
| Drug and gene relationship at DGIdb | |||
Expression of TMUB1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMUB1 | 83590 | 223153_x_at | 0.2338 | 0.5034 | |
| GSE26886 | TMUB1 | 83590 | 223153_x_at | 0.3726 | 0.0284 | |
| GSE45670 | TMUB1 | 83590 | 223153_x_at | 0.2308 | 0.0107 | |
| GSE53622 | TMUB1 | 83590 | 26097 | -0.2779 | 0.0000 | |
| GSE53624 | TMUB1 | 83590 | 47745 | -0.2203 | 0.0001 | |
| GSE63941 | TMUB1 | 83590 | 223153_x_at | -0.3200 | 0.1055 | |
| GSE77861 | TMUB1 | 83590 | 223153_x_at | 0.1440 | 0.5823 | |
| GSE97050 | TMUB1 | 83590 | A_33_P3268763 | -0.0395 | 0.8567 | |
| SRP007169 | TMUB1 | 83590 | RNAseq | -0.1545 | 0.7333 | |
| SRP008496 | TMUB1 | 83590 | RNAseq | -0.5699 | 0.0730 | |
| SRP064894 | TMUB1 | 83590 | RNAseq | 0.7103 | 0.0531 | |
| SRP133303 | TMUB1 | 83590 | RNAseq | 0.0432 | 0.8270 | |
| SRP159526 | TMUB1 | 83590 | RNAseq | -0.1467 | 0.4889 | |
| SRP193095 | TMUB1 | 83590 | RNAseq | -0.1200 | 0.3473 | |
| SRP219564 | TMUB1 | 83590 | RNAseq | -0.1783 | 0.4259 | |
| TCGA | TMUB1 | 83590 | RNAseq | -0.0640 | 0.2891 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMUB1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMUB1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMUB1 | 83590 | 2 | 4 | 24 | |
| GSE20123 | TMUB1 | 83590 | 2 | 4 | 24 | |
| GSE43470 | TMUB1 | 83590 | 2 | 5 | 36 | |
| GSE46452 | TMUB1 | 83590 | 7 | 2 | 50 | |
| GSE47630 | TMUB1 | 83590 | 5 | 9 | 26 | |
| GSE54993 | TMUB1 | 83590 | 3 | 3 | 64 | |
| GSE54994 | TMUB1 | 83590 | 5 | 8 | 40 | |
| GSE60625 | TMUB1 | 83590 | 0 | 0 | 11 | |
| GSE74703 | TMUB1 | 83590 | 2 | 4 | 30 | |
| GSE74704 | TMUB1 | 83590 | 1 | 4 | 15 | |
| TCGA | TMUB1 | 83590 | 26 | 25 | 45 |
Total number of gains: 55; Total number of losses: 68; Total Number of normals: 365.
Somatic mutations of TMUB1:
Generating mutation plots.
Highly correlated genes for TMUB1:
Showing top 20/227 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMUB1 | CHMP6 | 0.827214 | 3 | 0 | 3 |
| TMUB1 | DNAL4 | 0.802373 | 3 | 0 | 3 |
| TMUB1 | C19orf53 | 0.789671 | 3 | 0 | 3 |
| TMUB1 | P4HA3 | 0.774256 | 3 | 0 | 3 |
| TMUB1 | MAT1A | 0.76793 | 3 | 0 | 3 |
| TMUB1 | PPP2R5D | 0.759562 | 3 | 0 | 3 |
| TMUB1 | CLN3 | 0.759129 | 4 | 0 | 4 |
| TMUB1 | UBALD1 | 0.755895 | 3 | 0 | 3 |
| TMUB1 | STK11 | 0.755266 | 4 | 0 | 3 |
| TMUB1 | ADCY1 | 0.753887 | 3 | 0 | 3 |
| TMUB1 | FUZ | 0.750272 | 3 | 0 | 3 |
| TMUB1 | LRCH4 | 0.741791 | 3 | 0 | 3 |
| TMUB1 | PPIL2 | 0.739254 | 4 | 0 | 3 |
| TMUB1 | TBC1D10B | 0.736643 | 5 | 0 | 4 |
| TMUB1 | TCP10 | 0.735583 | 3 | 0 | 3 |
| TMUB1 | SETD1B | 0.730858 | 3 | 0 | 3 |
| TMUB1 | CHD5 | 0.728117 | 3 | 0 | 3 |
| TMUB1 | CCDC130 | 0.727334 | 4 | 0 | 4 |
| TMUB1 | CADM4 | 0.722364 | 4 | 0 | 4 |
| TMUB1 | TP53TG5 | 0.721305 | 3 | 0 | 3 |
For details and further investigation, click here
