TPPP2

 

Full name: tubulin polymerization promoting protein family member 2 Alias Symbol: p25beta|p18|CT152
Type: protein-coding gene Cytoband: 14q11.2
Entrez ID: 122664 HGNC ID: HGNC:19293 Ensembl Gene: ENSG00000179636 OMIM ID: 616956

 

Expression of TPPP2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TPPP2 122664 1559785_at -0.2213 0.3586
GSE26886 TPPP2 122664 231140_at 0.0909 0.4392
GSE45670 TPPP2 122664 1559785_at 0.0008 0.9948
GSE53622 TPPP2 122664 10859 -0.0114 0.9167
GSE53624 TPPP2 122664 10859 -0.3345 0.0001
GSE63941 TPPP2 122664 231140_at 0.1571 0.2860
GSE77861 TPPP2 122664 231140_at -0.0695 0.6561

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by TPPP2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TPPP2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TPPP2 122664 9 3 18
GSE20123 TPPP2 122664 8 3 19
GSE43470 TPPP2 122664 7 1 35
GSE46452 TPPP2 122664 19 2 38
GSE47630 TPPP2 122664 10 10 20
GSE54993 TPPP2 122664 3 11 56
GSE54994 TPPP2 122664 18 5 30
GSE60625 TPPP2 122664 0 2 9
GSE74703 TPPP2 122664 6 1 29
GSE74704 TPPP2 122664 4 2 14
TCGA TPPP2 122664 27 16 53

Total number of gains: 111; Total number of losses: 56; Total Number of normals: 321.  

 

Somatic mutations of TPPP2:

 

Generating mutation plots.

 

Highly correlated genes for TPPP2:

 

Showing all 16 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TPPP2POU3F20.667713303
TPPP2BPIFA10.611502303
TPPP2C10orf910.595251303
TPPP2LINC004790.587624303
TPPP2CACNG50.587621404
TPPP2PRM10.576918303
TPPP2OR2H10.55727303
TPPP2TGIF2LY0.555084403
TPPP2MAPK8IP10.544711403
TPPP2ZNF1690.544607403
TPPP2TNNT30.542468403
TPPP2TMEM950.53979403
TPPP2ZNF2140.533269403
TPPP2ACTL6B0.530457603
TPPP2TRABD2B0.516179403
TPPP2SLFNL1-AS10.512681303

For details and further investigation, click here