| Full name: POU class 3 homeobox 2 | Alias Symbol: POUF3|BRN2|OCT7 | ||
| Type: protein-coding gene | Cytoband: 6q16.1 | ||
| Entrez ID: 5454 | HGNC ID: HGNC:9215 | Ensembl Gene: ENSG00000184486 | OMIM ID: 600494 |
Expression of POU3F2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | POU3F2 | 5454 | 207084_at | -0.0968 | 0.6688 | |
| GSE20347 | POU3F2 | 5454 | 207084_at | 0.0508 | 0.5311 | |
| GSE23400 | POU3F2 | 5454 | 207084_at | -0.1000 | 0.0000 | |
| GSE26886 | POU3F2 | 5454 | 207084_at | 0.1376 | 0.1883 | |
| GSE29001 | POU3F2 | 5454 | 207084_at | 0.0699 | 0.6089 | |
| GSE38129 | POU3F2 | 5454 | 207084_at | 0.0880 | 0.3690 | |
| GSE45670 | POU3F2 | 5454 | 207084_at | -0.0021 | 0.9867 | |
| GSE53622 | POU3F2 | 5454 | 30166 | -0.1371 | 0.4437 | |
| GSE53624 | POU3F2 | 5454 | 30166 | 0.3591 | 0.0197 | |
| GSE63941 | POU3F2 | 5454 | 207084_at | 0.1510 | 0.3551 | |
| GSE77861 | POU3F2 | 5454 | 242455_at | -0.1086 | 0.3999 | |
| TCGA | POU3F2 | 5454 | RNAseq | 3.6974 | 0.0008 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by POU3F2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of POU3F2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | POU3F2 | 5454 | 1 | 3 | 26 | |
| GSE20123 | POU3F2 | 5454 | 1 | 2 | 27 | |
| GSE43470 | POU3F2 | 5454 | 3 | 0 | 40 | |
| GSE46452 | POU3F2 | 5454 | 2 | 11 | 46 | |
| GSE47630 | POU3F2 | 5454 | 8 | 6 | 26 | |
| GSE54993 | POU3F2 | 5454 | 3 | 2 | 65 | |
| GSE54994 | POU3F2 | 5454 | 8 | 8 | 37 | |
| GSE60625 | POU3F2 | 5454 | 0 | 1 | 10 | |
| GSE74703 | POU3F2 | 5454 | 2 | 0 | 34 | |
| GSE74704 | POU3F2 | 5454 | 0 | 0 | 20 | |
| TCGA | POU3F2 | 5454 | 6 | 24 | 66 |
Total number of gains: 34; Total number of losses: 57; Total Number of normals: 397.
Somatic mutations of POU3F2:
Generating mutation plots.
Highly correlated genes for POU3F2:
Showing top 20/193 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| POU3F2 | TPPP2 | 0.667713 | 3 | 0 | 3 |
| POU3F2 | OPRK1 | 0.642979 | 4 | 0 | 4 |
| POU3F2 | B4GALNT1 | 0.642195 | 3 | 0 | 3 |
| POU3F2 | FBXL18 | 0.641888 | 3 | 0 | 3 |
| POU3F2 | ZC2HC1C | 0.64093 | 4 | 0 | 4 |
| POU3F2 | GBX2 | 0.636698 | 3 | 0 | 3 |
| POU3F2 | GPR146 | 0.619769 | 3 | 0 | 3 |
| POU3F2 | ADAMTSL5 | 0.615147 | 3 | 0 | 3 |
| POU3F2 | LALBA | 0.608035 | 3 | 0 | 3 |
| POU3F2 | C11orf16 | 0.603344 | 6 | 0 | 5 |
| POU3F2 | OR10H1 | 0.596042 | 4 | 0 | 3 |
| POU3F2 | POU3F3 | 0.592915 | 3 | 0 | 3 |
| POU3F2 | SYT13 | 0.59288 | 4 | 0 | 4 |
| POU3F2 | DCX | 0.589193 | 5 | 0 | 4 |
| POU3F2 | INCENP | 0.587443 | 4 | 0 | 4 |
| POU3F2 | RS1 | 0.581202 | 3 | 0 | 3 |
| POU3F2 | KRT81 | 0.580681 | 3 | 0 | 3 |
| POU3F2 | MOGAT2 | 0.578657 | 7 | 0 | 5 |
| POU3F2 | SLC13A2 | 0.577996 | 6 | 0 | 4 |
| POU3F2 | FOXE3 | 0.57731 | 4 | 0 | 3 |
For details and further investigation, click here
