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Severity: Warning

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Line Number: 123

Backtrace:

File: /data/webapp/var/www/html/ESCCdb/application/controllers/Result_pages.php
Line: 123
Function: exec

File: /data/webapp/var/www/html/ESCCdb/application/controllers/Result_pages.php
Line: 387
Function: drawSurvPlot

File: /data/webapp/var/www/html/ESCCdb/index.php
Line: 315
Function: require_once

Multi-Omics Database of ESCC

 

BPIFA1

 

Full name: BPI fold containing family A member 1 Alias Symbol: LUNX|bA49G10.5|SPLUNC1
Type: protein-coding gene Cytoband: 20q11.21
Entrez ID: 51297 HGNC ID: HGNC:15749 Ensembl Gene: ENSG00000198183 OMIM ID: 607412
Drug and gene relationship at DGIdb

 

Expression of BPIFA1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 BPIFA1 51297 220542_s_at -0.1466 0.4709
GSE20347 BPIFA1 51297 220542_s_at 0.0553 0.5738
GSE23400 BPIFA1 51297 220542_s_at -0.0953 0.0485
GSE26886 BPIFA1 51297 220542_s_at -0.1152 0.4217
GSE29001 BPIFA1 51297 220542_s_at -0.2414 0.2011
GSE38129 BPIFA1 51297 220542_s_at -0.0235 0.8264
GSE45670 BPIFA1 51297 220542_s_at 0.0796 0.5750
GSE53622 BPIFA1 51297 61685 0.1863 0.0812
GSE53624 BPIFA1 51297 61685 -0.1513 0.3520
GSE63941 BPIFA1 51297 220542_s_at 0.1295 0.5175
GSE77861 BPIFA1 51297 220542_s_at -0.1460 0.3019
GSE97050 BPIFA1 51297 A_33_P3245228 0.2972 0.2051

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by BPIFA1 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  

Copy number change of BPIFA1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 BPIFA1 51297 15 0 15
GSE20123 BPIFA1 51297 15 0 15
GSE43470 BPIFA1 51297 12 0 31
GSE46452 BPIFA1 51297 29 0 30
GSE47630 BPIFA1 51297 24 1 15
GSE54993 BPIFA1 51297 0 19 51
GSE54994 BPIFA1 51297 26 1 26
GSE60625 BPIFA1 51297 0 0 11
GSE74703 BPIFA1 51297 11 0 25
GSE74704 BPIFA1 51297 10 0 10
TCGA BPIFA1 51297 50 1 45

Total number of gains: 192; Total number of losses: 22; Total Number of normals: 274.  

 

Somatic mutations of BPIFA1:

 

Generating mutation plots.

 

Highly correlated genes for BPIFA1:

 

Showing top 20/700 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
BPIFA1RPS6KA60.711619404
BPIFA1RHAG0.703786303
BPIFA1CCDC870.698509404
BPIFA1SLC17A30.696378605
BPIFA1FOLH10.694696404
BPIFA1SPINT30.689849505
BPIFA1MC4R0.689799404
BPIFA1KIR2DL20.688961504
BPIFA1P2RY40.683659605
BPIFA1RNF1860.683073403
BPIFA1SIGLEC60.68049505
BPIFA1RAB3IL10.679919505
BPIFA1CTAGE10.679801403
BPIFA1PRORY0.677686303
BPIFA1CCL10.675919505
BPIFA1DAB10.675493504
BPIFA1CRX0.675234404
BPIFA1RAB33A0.675222303
BPIFA1TAS2R80.671268505
BPIFA1NXPE40.671198504

For details and further investigation, click here