| Full name: actin like 6B | Alias Symbol: BAF53B | ||
| Type: protein-coding gene | Cytoband: 7q22.1 | ||
| Entrez ID: 51412 | HGNC ID: HGNC:160 | Ensembl Gene: ENSG00000077080 | OMIM ID: 612458 |
| Drug and gene relationship at DGIdb | |||
Expression of ACTL6B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ACTL6B | 51412 | 206014_at | -0.2292 | 0.4047 | |
| GSE20347 | ACTL6B | 51412 | 206014_at | -0.1216 | 0.1632 | |
| GSE23400 | ACTL6B | 51412 | 206014_at | -0.1174 | 0.0007 | |
| GSE26886 | ACTL6B | 51412 | 206014_at | 0.2743 | 0.0133 | |
| GSE29001 | ACTL6B | 51412 | 206014_at | -0.2575 | 0.1300 | |
| GSE38129 | ACTL6B | 51412 | 206014_at | -0.1025 | 0.3358 | |
| GSE45670 | ACTL6B | 51412 | 206014_at | 0.0795 | 0.5350 | |
| GSE53622 | ACTL6B | 51412 | 67319 | 0.2286 | 0.0064 | |
| GSE53624 | ACTL6B | 51412 | 67319 | 0.5121 | 0.0000 | |
| GSE63941 | ACTL6B | 51412 | 206014_at | 0.2761 | 0.0914 | |
| GSE77861 | ACTL6B | 51412 | 206014_at | -0.1741 | 0.1750 | |
| GSE97050 | ACTL6B | 51412 | A_23_P145681 | -0.0681 | 0.7691 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ACTL6B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ACTL6B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ACTL6B | 51412 | 13 | 0 | 17 | |
| GSE20123 | ACTL6B | 51412 | 13 | 0 | 17 | |
| GSE43470 | ACTL6B | 51412 | 7 | 2 | 34 | |
| GSE46452 | ACTL6B | 51412 | 11 | 1 | 47 | |
| GSE47630 | ACTL6B | 51412 | 7 | 3 | 30 | |
| GSE54993 | ACTL6B | 51412 | 1 | 9 | 60 | |
| GSE54994 | ACTL6B | 51412 | 16 | 3 | 34 | |
| GSE60625 | ACTL6B | 51412 | 0 | 0 | 11 | |
| GSE74703 | ACTL6B | 51412 | 7 | 1 | 28 | |
| GSE74704 | ACTL6B | 51412 | 9 | 0 | 11 | |
| TCGA | ACTL6B | 51412 | 53 | 6 | 37 |
Total number of gains: 137; Total number of losses: 25; Total Number of normals: 326.
Somatic mutations of ACTL6B:
Generating mutation plots.
Highly correlated genes for ACTL6B:
Showing top 20/1091 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ACTL6B | ANKRD33B | 0.775096 | 3 | 0 | 3 |
| ACTL6B | PLA2G12B | 0.774029 | 4 | 0 | 4 |
| ACTL6B | IQCD | 0.764734 | 3 | 0 | 3 |
| ACTL6B | WNT9A | 0.755329 | 3 | 0 | 3 |
| ACTL6B | HSD3B1 | 0.749557 | 3 | 0 | 3 |
| ACTL6B | TSPAN11 | 0.742419 | 3 | 0 | 3 |
| ACTL6B | SLC24A4 | 0.732074 | 3 | 0 | 3 |
| ACTL6B | SHISA7 | 0.73009 | 4 | 0 | 4 |
| ACTL6B | UMOD | 0.717025 | 4 | 0 | 4 |
| ACTL6B | LY6G6C | 0.713291 | 3 | 0 | 3 |
| ACTL6B | RETN | 0.709103 | 5 | 0 | 5 |
| ACTL6B | IGSF21 | 0.707623 | 4 | 0 | 4 |
| ACTL6B | HSF4 | 0.70611 | 3 | 0 | 3 |
| ACTL6B | PAX5 | 0.701597 | 3 | 0 | 3 |
| ACTL6B | CPLX2 | 0.701451 | 5 | 0 | 4 |
| ACTL6B | PGC | 0.699186 | 4 | 0 | 3 |
| ACTL6B | TLR8 | 0.697911 | 5 | 0 | 4 |
| ACTL6B | TFF1 | 0.692691 | 3 | 0 | 3 |
| ACTL6B | MAGEA8 | 0.687813 | 3 | 0 | 3 |
| ACTL6B | RXFP3 | 0.682779 | 6 | 0 | 5 |
For details and further investigation, click here
