| Full name: UFM1 specific ligase 1 | Alias Symbol: NLBP|Maxer|RCAD | ||
| Type: protein-coding gene | Cytoband: 6q16.1 | ||
| Entrez ID: 23376 | HGNC ID: HGNC:23039 | Ensembl Gene: ENSG00000014123 | OMIM ID: 613372 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of UFL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UFL1 | 23376 | 212633_at | -0.9128 | 0.0939 | |
| GSE20347 | UFL1 | 23376 | 212633_at | -0.9376 | 0.0000 | |
| GSE23400 | UFL1 | 23376 | 212633_at | -0.6151 | 0.0000 | |
| GSE26886 | UFL1 | 23376 | 212633_at | -0.7086 | 0.0035 | |
| GSE29001 | UFL1 | 23376 | 212633_at | -0.6401 | 0.0303 | |
| GSE38129 | UFL1 | 23376 | 212633_at | -0.8002 | 0.0000 | |
| GSE45670 | UFL1 | 23376 | 212633_at | -0.4537 | 0.0096 | |
| GSE53622 | UFL1 | 23376 | 166205 | -0.5291 | 0.0000 | |
| GSE53624 | UFL1 | 23376 | 166205 | -0.6291 | 0.0000 | |
| GSE63941 | UFL1 | 23376 | 212633_at | -0.9831 | 0.0284 | |
| GSE77861 | UFL1 | 23376 | 212633_at | -0.9082 | 0.0026 | |
| GSE97050 | UFL1 | 23376 | A_23_P30956 | -0.4722 | 0.1076 | |
| SRP007169 | UFL1 | 23376 | RNAseq | -0.7494 | 0.0376 | |
| SRP008496 | UFL1 | 23376 | RNAseq | -0.7173 | 0.0003 | |
| SRP064894 | UFL1 | 23376 | RNAseq | -0.7123 | 0.0235 | |
| SRP133303 | UFL1 | 23376 | RNAseq | -0.3726 | 0.0227 | |
| SRP159526 | UFL1 | 23376 | RNAseq | -0.8774 | 0.0003 | |
| SRP193095 | UFL1 | 23376 | RNAseq | -0.9481 | 0.0000 | |
| SRP219564 | UFL1 | 23376 | RNAseq | -0.7611 | 0.0221 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by UFL1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of UFL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UFL1 | 23376 | 1 | 3 | 26 | |
| GSE20123 | UFL1 | 23376 | 1 | 2 | 27 | |
| GSE43470 | UFL1 | 23376 | 3 | 2 | 38 | |
| GSE46452 | UFL1 | 23376 | 2 | 11 | 46 | |
| GSE47630 | UFL1 | 23376 | 8 | 6 | 26 | |
| GSE54993 | UFL1 | 23376 | 3 | 2 | 65 | |
| GSE54994 | UFL1 | 23376 | 8 | 8 | 37 | |
| GSE60625 | UFL1 | 23376 | 0 | 1 | 10 | |
| GSE74703 | UFL1 | 23376 | 2 | 2 | 32 | |
| GSE74704 | UFL1 | 23376 | 0 | 0 | 20 | |
| TCGA | UFL1 | 23376 | 5 | 25 | 66 |
Total number of gains: 33; Total number of losses: 62; Total Number of normals: 393.
Somatic mutations of UFL1:
Generating mutation plots.
Highly correlated genes for UFL1:
Showing top 20/1636 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UFL1 | SNRNP27 | 0.780571 | 3 | 0 | 3 |
| UFL1 | RBM20 | 0.777305 | 4 | 0 | 4 |
| UFL1 | FCHO2 | 0.774716 | 7 | 0 | 7 |
| UFL1 | SPAG17 | 0.774613 | 4 | 0 | 4 |
| UFL1 | GOLGA4 | 0.767297 | 9 | 0 | 9 |
| UFL1 | CCDC25 | 0.764865 | 3 | 0 | 3 |
| UFL1 | UBL3 | 0.764095 | 10 | 0 | 10 |
| UFL1 | VDAC3 | 0.763214 | 3 | 0 | 3 |
| UFL1 | ZNF514 | 0.754757 | 3 | 0 | 3 |
| UFL1 | FBXO3 | 0.754435 | 10 | 0 | 10 |
| UFL1 | DOCK9 | 0.753764 | 11 | 0 | 11 |
| UFL1 | CCNYL1 | 0.751411 | 5 | 0 | 5 |
| UFL1 | DPH3 | 0.749731 | 3 | 0 | 3 |
| UFL1 | RPL14 | 0.749722 | 5 | 0 | 5 |
| UFL1 | ZCCHC9 | 0.748861 | 4 | 0 | 4 |
| UFL1 | EIF4E3 | 0.748003 | 6 | 0 | 6 |
| UFL1 | C12orf29 | 0.747222 | 11 | 0 | 11 |
| UFL1 | MTM1 | 0.746958 | 3 | 0 | 3 |
| UFL1 | TMEM61 | 0.742882 | 4 | 0 | 4 |
| UFL1 | TRIP11 | 0.740614 | 5 | 0 | 5 |
For details and further investigation, click here
