| Full name: FCH and mu domain containing endocytic adaptor 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 5q13.2 | ||
| Entrez ID: 115548 | HGNC ID: HGNC:25180 | Ensembl Gene: ENSG00000157107 | OMIM ID: 613438 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of FCHO2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FCHO2 | 115548 | 228220_at | -1.4449 | 0.0248 | |
| GSE26886 | FCHO2 | 115548 | 228220_at | -2.5450 | 0.0000 | |
| GSE45670 | FCHO2 | 115548 | 228220_at | -0.8039 | 0.0043 | |
| GSE53622 | FCHO2 | 115548 | 6911 | -1.4512 | 0.0000 | |
| GSE53624 | FCHO2 | 115548 | 72620 | -1.8768 | 0.0000 | |
| GSE63941 | FCHO2 | 115548 | 228220_at | -0.7481 | 0.1787 | |
| GSE77861 | FCHO2 | 115548 | 228220_at | -1.8618 | 0.0004 | |
| GSE97050 | FCHO2 | 115548 | A_23_P420610 | -0.8199 | 0.1403 | |
| SRP007169 | FCHO2 | 115548 | RNAseq | -2.5284 | 0.0000 | |
| SRP008496 | FCHO2 | 115548 | RNAseq | -2.3991 | 0.0000 | |
| SRP064894 | FCHO2 | 115548 | RNAseq | -1.8216 | 0.0000 | |
| SRP133303 | FCHO2 | 115548 | RNAseq | -1.1876 | 0.0000 | |
| SRP159526 | FCHO2 | 115548 | RNAseq | -2.0692 | 0.0000 | |
| SRP193095 | FCHO2 | 115548 | RNAseq | -2.0602 | 0.0000 | |
| SRP219564 | FCHO2 | 115548 | RNAseq | -1.7943 | 0.0016 | |
| TCGA | FCHO2 | 115548 | RNAseq | -0.2367 | 0.0010 |
Upregulated datasets: 0; Downregulated datasets: 12.
Survival by FCHO2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FCHO2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FCHO2 | 115548 | 1 | 13 | 16 | |
| GSE20123 | FCHO2 | 115548 | 1 | 13 | 16 | |
| GSE43470 | FCHO2 | 115548 | 1 | 13 | 29 | |
| GSE46452 | FCHO2 | 115548 | 0 | 28 | 31 | |
| GSE47630 | FCHO2 | 115548 | 1 | 19 | 20 | |
| GSE54993 | FCHO2 | 115548 | 8 | 1 | 61 | |
| GSE54994 | FCHO2 | 115548 | 1 | 19 | 33 | |
| GSE60625 | FCHO2 | 115548 | 0 | 0 | 11 | |
| GSE74703 | FCHO2 | 115548 | 1 | 9 | 26 | |
| GSE74704 | FCHO2 | 115548 | 1 | 6 | 13 | |
| TCGA | FCHO2 | 115548 | 4 | 51 | 41 |
Total number of gains: 19; Total number of losses: 172; Total Number of normals: 297.
Somatic mutations of FCHO2:
Generating mutation plots.
Highly correlated genes for FCHO2:
Showing top 20/1899 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FCHO2 | PADI1 | 0.881564 | 4 | 0 | 4 |
| FCHO2 | GDPD3 | 0.87893 | 6 | 0 | 6 |
| FCHO2 | VSIG10L | 0.877928 | 6 | 0 | 6 |
| FCHO2 | ECM1 | 0.873068 | 6 | 0 | 6 |
| FCHO2 | PRSS27 | 0.872619 | 6 | 0 | 6 |
| FCHO2 | ANXA9 | 0.871458 | 7 | 0 | 7 |
| FCHO2 | SLC16A6 | 0.871083 | 7 | 0 | 7 |
| FCHO2 | SPNS2 | 0.870938 | 5 | 0 | 5 |
| FCHO2 | SCEL | 0.870022 | 6 | 0 | 6 |
| FCHO2 | CYSRT1 | 0.870021 | 6 | 0 | 6 |
| FCHO2 | GYS2 | 0.867685 | 6 | 0 | 6 |
| FCHO2 | SPINK5 | 0.867185 | 6 | 0 | 6 |
| FCHO2 | SCNN1B | 0.866803 | 6 | 0 | 6 |
| FCHO2 | GBP6 | 0.865207 | 4 | 0 | 4 |
| FCHO2 | RANBP9 | 0.863986 | 7 | 0 | 7 |
| FCHO2 | TMPRSS11B | 0.863331 | 6 | 0 | 6 |
| FCHO2 | LRP10 | 0.860632 | 7 | 0 | 7 |
| FCHO2 | SPINK7 | 0.86034 | 6 | 0 | 6 |
| FCHO2 | CPPED1 | 0.859523 | 7 | 0 | 7 |
| FCHO2 | SFTA2 | 0.858921 | 4 | 0 | 4 |
For details and further investigation, click here
