| Full name: sperm associated antigen 17 | Alias Symbol: FLJ34497|PF6|RP4-776P7.2|CT143 | ||
| Type: protein-coding gene | Cytoband: 1p12 | ||
| Entrez ID: 200162 | HGNC ID: HGNC:26620 | Ensembl Gene: ENSG00000155761 | OMIM ID: 616554 |
| Drug and gene relationship at DGIdb | |||
Expression of SPAG17:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SPAG17 | 200162 | 233516_s_at | -2.4173 | 0.0493 | |
| GSE26886 | SPAG17 | 200162 | 233516_s_at | -3.6525 | 0.0000 | |
| GSE45670 | SPAG17 | 200162 | 233516_s_at | -0.3359 | 0.5154 | |
| GSE63941 | SPAG17 | 200162 | 233516_s_at | 0.2939 | 0.5577 | |
| GSE77861 | SPAG17 | 200162 | 233516_s_at | -1.4916 | 0.0020 | |
| GSE97050 | SPAG17 | 200162 | A_23_P319783 | -0.3104 | 0.2956 | |
| SRP007169 | SPAG17 | 200162 | RNAseq | -4.4546 | 0.0000 | |
| SRP008496 | SPAG17 | 200162 | RNAseq | -4.7020 | 0.0000 | |
| SRP064894 | SPAG17 | 200162 | RNAseq | -1.5549 | 0.0007 | |
| SRP133303 | SPAG17 | 200162 | RNAseq | -2.0343 | 0.0000 | |
| SRP159526 | SPAG17 | 200162 | RNAseq | -3.1265 | 0.0000 | |
| SRP219564 | SPAG17 | 200162 | RNAseq | -2.3803 | 0.0155 | |
| TCGA | SPAG17 | 200162 | RNAseq | 0.5762 | 0.1694 |
Upregulated datasets: 0; Downregulated datasets: 9.
Survival by SPAG17 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of SPAG17:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPAG17 | 200162 | 1 | 8 | 21 | |
| GSE20123 | SPAG17 | 200162 | 0 | 8 | 22 | |
| GSE43470 | SPAG17 | 200162 | 0 | 3 | 40 | |
| GSE46452 | SPAG17 | 200162 | 2 | 1 | 56 | |
| GSE47630 | SPAG17 | 200162 | 9 | 5 | 26 | |
| GSE54993 | SPAG17 | 200162 | 0 | 1 | 69 | |
| GSE54994 | SPAG17 | 200162 | 11 | 1 | 41 | |
| GSE60625 | SPAG17 | 200162 | 0 | 0 | 11 | |
| GSE74703 | SPAG17 | 200162 | 0 | 3 | 33 | |
| GSE74704 | SPAG17 | 200162 | 0 | 4 | 16 | |
| TCGA | SPAG17 | 200162 | 15 | 28 | 53 |
Total number of gains: 38; Total number of losses: 62; Total Number of normals: 388.
Somatic mutations of SPAG17:
Generating mutation plots.
Highly correlated genes for SPAG17:
Showing top 20/1037 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPAG17 | TMEM40 | 0.847093 | 5 | 0 | 5 |
| SPAG17 | CPPED1 | 0.845446 | 4 | 0 | 4 |
| SPAG17 | PPP1R3C | 0.842557 | 4 | 0 | 4 |
| SPAG17 | ST6GALNAC1 | 0.838765 | 5 | 0 | 5 |
| SPAG17 | MOSPD1 | 0.836783 | 4 | 0 | 4 |
| SPAG17 | TMPRSS11B | 0.835571 | 5 | 0 | 5 |
| SPAG17 | TMPRSS2 | 0.833076 | 3 | 0 | 3 |
| SPAG17 | MAB21L3 | 0.831483 | 4 | 0 | 4 |
| SPAG17 | CHIC2 | 0.829959 | 3 | 0 | 3 |
| SPAG17 | ATP13A4 | 0.829855 | 5 | 0 | 5 |
| SPAG17 | CAPN14 | 0.829852 | 4 | 0 | 4 |
| SPAG17 | FCHO2 | 0.829734 | 4 | 0 | 4 |
| SPAG17 | A2ML1 | 0.828272 | 5 | 0 | 5 |
| SPAG17 | SCNN1B | 0.828011 | 5 | 0 | 5 |
| SPAG17 | CLCA4 | 0.826139 | 5 | 0 | 5 |
| SPAG17 | KAT2B | 0.822601 | 4 | 0 | 4 |
| SPAG17 | SASH1 | 0.821502 | 5 | 0 | 5 |
| SPAG17 | CLIC3 | 0.820268 | 5 | 0 | 5 |
| SPAG17 | PRSS3 | 0.8201 | 5 | 0 | 5 |
| SPAG17 | VSIG10L | 0.818747 | 5 | 0 | 5 |
For details and further investigation, click here
