| Full name: ribosomal protein L14 | Alias Symbol: L14|hRL14|RL14|CTG-B33 | ||
| Type: protein-coding gene | Cytoband: 3p22.1 | ||
| Entrez ID: 9045 | HGNC ID: HGNC:10305 | Ensembl Gene: ENSG00000188846 | OMIM ID: 617414 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of RPL14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPL14 | 9045 | 213588_x_at | -0.2706 | 0.3555 | |
| GSE20347 | RPL14 | 9045 | 213588_x_at | -0.4888 | 0.0001 | |
| GSE23400 | RPL14 | 9045 | 213588_x_at | -0.3988 | 0.0000 | |
| GSE26886 | RPL14 | 9045 | 213588_x_at | 0.0056 | 0.9647 | |
| GSE29001 | RPL14 | 9045 | 213588_x_at | -0.3495 | 0.0510 | |
| GSE38129 | RPL14 | 9045 | 213588_x_at | -0.4915 | 0.0000 | |
| GSE45670 | RPL14 | 9045 | 213588_x_at | -0.4691 | 0.0003 | |
| GSE63941 | RPL14 | 9045 | 213588_x_at | -0.0159 | 0.9521 | |
| GSE77861 | RPL14 | 9045 | 213588_x_at | -0.5739 | 0.0082 | |
| GSE97050 | RPL14 | 9045 | A_23_P18292 | -0.6733 | 0.0897 | |
| SRP007169 | RPL14 | 9045 | RNAseq | -1.4197 | 0.0000 | |
| SRP008496 | RPL14 | 9045 | RNAseq | -1.2409 | 0.0000 | |
| SRP064894 | RPL14 | 9045 | RNAseq | -0.8418 | 0.0009 | |
| SRP133303 | RPL14 | 9045 | RNAseq | -0.9545 | 0.0000 | |
| SRP159526 | RPL14 | 9045 | RNAseq | -1.1476 | 0.0000 | |
| SRP193095 | RPL14 | 9045 | RNAseq | -1.3942 | 0.0000 | |
| SRP219564 | RPL14 | 9045 | RNAseq | -0.7550 | 0.0758 | |
| TCGA | RPL14 | 9045 | RNAseq | -0.1155 | 0.0557 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by RPL14 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of RPL14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPL14 | 9045 | 0 | 19 | 11 | |
| GSE20123 | RPL14 | 9045 | 0 | 19 | 11 | |
| GSE43470 | RPL14 | 9045 | 0 | 20 | 23 | |
| GSE46452 | RPL14 | 9045 | 2 | 17 | 40 | |
| GSE47630 | RPL14 | 9045 | 2 | 24 | 14 | |
| GSE54993 | RPL14 | 9045 | 7 | 2 | 61 | |
| GSE54994 | RPL14 | 9045 | 1 | 33 | 19 | |
| GSE60625 | RPL14 | 9045 | 5 | 0 | 6 | |
| GSE74703 | RPL14 | 9045 | 0 | 16 | 20 | |
| GSE74704 | RPL14 | 9045 | 0 | 13 | 7 | |
| TCGA | RPL14 | 9045 | 1 | 71 | 24 |
Total number of gains: 18; Total number of losses: 234; Total Number of normals: 236.
Somatic mutations of RPL14:
Generating mutation plots.
Highly correlated genes for RPL14:
Showing top 20/919 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPL14 | TIFA | 0.806882 | 3 | 0 | 3 |
| RPL14 | RPL29 | 0.791401 | 8 | 0 | 7 |
| RPL14 | MTMR10 | 0.788661 | 3 | 0 | 3 |
| RPL14 | ZMYM5 | 0.774126 | 3 | 0 | 3 |
| RPL14 | NFIA | 0.770367 | 5 | 0 | 4 |
| RPL14 | LRRK2 | 0.769982 | 3 | 0 | 3 |
| RPL14 | BRK1 | 0.767357 | 3 | 0 | 3 |
| RPL14 | RPL32 | 0.75548 | 8 | 0 | 8 |
| RPL14 | KCTD6 | 0.753399 | 4 | 0 | 4 |
| RPL14 | ZYG11B | 0.752958 | 3 | 0 | 3 |
| RPL14 | ARIH1 | 0.75209 | 3 | 0 | 3 |
| RPL14 | UFL1 | 0.749722 | 5 | 0 | 5 |
| RPL14 | NDUFAF2 | 0.74676 | 3 | 0 | 3 |
| RPL14 | QRICH1 | 0.746233 | 6 | 0 | 6 |
| RPL14 | CWC27 | 0.744317 | 3 | 0 | 3 |
| RPL14 | SAMD5 | 0.736573 | 3 | 0 | 3 |
| RPL14 | ABHD14B | 0.736166 | 3 | 0 | 3 |
| RPL14 | PAQR8 | 0.735475 | 3 | 0 | 3 |
| RPL14 | WBP4 | 0.734024 | 3 | 0 | 3 |
| RPL14 | MRPS25 | 0.732586 | 3 | 0 | 3 |
For details and further investigation, click here
