| Full name: F-box protein 3 | Alias Symbol: FBX3|FBA | ||
| Type: protein-coding gene | Cytoband: 11p13 | ||
| Entrez ID: 26273 | HGNC ID: HGNC:13582 | Ensembl Gene: ENSG00000110429 | OMIM ID: 609089 |
| Drug and gene relationship at DGIdb | |||
Expression of FBXO3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FBXO3 | 26273 | 218432_at | -1.2974 | 0.0171 | |
| GSE20347 | FBXO3 | 26273 | 218432_at | -1.8291 | 0.0000 | |
| GSE23400 | FBXO3 | 26273 | 218432_at | -0.9569 | 0.0000 | |
| GSE26886 | FBXO3 | 26273 | 218432_at | -2.1901 | 0.0000 | |
| GSE29001 | FBXO3 | 26273 | 218432_at | -1.3854 | 0.0062 | |
| GSE38129 | FBXO3 | 26273 | 218432_at | -1.4817 | 0.0000 | |
| GSE45670 | FBXO3 | 26273 | 218432_at | -0.9249 | 0.0001 | |
| GSE53622 | FBXO3 | 26273 | 141790 | -0.2011 | 0.0066 | |
| GSE53624 | FBXO3 | 26273 | 17819 | -1.4574 | 0.0000 | |
| GSE63941 | FBXO3 | 26273 | 218432_at | -0.9176 | 0.0161 | |
| GSE77861 | FBXO3 | 26273 | 218432_at | -1.1770 | 0.0397 | |
| GSE97050 | FBXO3 | 26273 | A_23_P363831 | 0.1993 | 0.3673 | |
| SRP007169 | FBXO3 | 26273 | RNAseq | -1.8864 | 0.0000 | |
| SRP008496 | FBXO3 | 26273 | RNAseq | -1.6057 | 0.0000 | |
| SRP064894 | FBXO3 | 26273 | RNAseq | -1.4150 | 0.0000 | |
| SRP133303 | FBXO3 | 26273 | RNAseq | -0.4311 | 0.0495 | |
| SRP159526 | FBXO3 | 26273 | RNAseq | -1.1419 | 0.0005 | |
| SRP193095 | FBXO3 | 26273 | RNAseq | -1.0202 | 0.0000 | |
| SRP219564 | FBXO3 | 26273 | RNAseq | -1.0992 | 0.0001 | |
| TCGA | FBXO3 | 26273 | RNAseq | -0.1652 | 0.0031 |
Upregulated datasets: 0; Downregulated datasets: 13.
Survival by FBXO3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FBXO3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FBXO3 | 26273 | 1 | 6 | 23 | |
| GSE20123 | FBXO3 | 26273 | 1 | 5 | 24 | |
| GSE43470 | FBXO3 | 26273 | 2 | 4 | 37 | |
| GSE46452 | FBXO3 | 26273 | 7 | 5 | 47 | |
| GSE47630 | FBXO3 | 26273 | 3 | 10 | 27 | |
| GSE54993 | FBXO3 | 26273 | 3 | 1 | 66 | |
| GSE54994 | FBXO3 | 26273 | 4 | 9 | 40 | |
| GSE60625 | FBXO3 | 26273 | 0 | 0 | 11 | |
| GSE74703 | FBXO3 | 26273 | 2 | 2 | 32 | |
| GSE74704 | FBXO3 | 26273 | 0 | 3 | 17 | |
| TCGA | FBXO3 | 26273 | 13 | 24 | 59 |
Total number of gains: 36; Total number of losses: 69; Total Number of normals: 383.
Somatic mutations of FBXO3:
Generating mutation plots.
Highly correlated genes for FBXO3:
Showing top 20/1597 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FBXO3 | SPAG16 | 0.793873 | 10 | 0 | 10 |
| FBXO3 | KCTD6 | 0.788613 | 6 | 0 | 6 |
| FBXO3 | ERI2 | 0.7689 | 3 | 0 | 3 |
| FBXO3 | SLC46A2 | 0.76258 | 6 | 0 | 6 |
| FBXO3 | FCHO2 | 0.759666 | 7 | 0 | 6 |
| FBXO3 | UBL3 | 0.758998 | 11 | 0 | 9 |
| FBXO3 | TSG101 | 0.758305 | 12 | 0 | 12 |
| FBXO3 | CGNL1 | 0.75828 | 6 | 0 | 6 |
| FBXO3 | LNX1 | 0.75809 | 6 | 0 | 5 |
| FBXO3 | CNN3 | 0.756191 | 8 | 0 | 8 |
| FBXO3 | PEX2 | 0.755305 | 3 | 0 | 3 |
| FBXO3 | MOB4 | 0.754916 | 10 | 0 | 10 |
| FBXO3 | UFL1 | 0.754435 | 10 | 0 | 10 |
| FBXO3 | BNIPL | 0.753703 | 6 | 0 | 5 |
| FBXO3 | SNORA68 | 0.751008 | 4 | 0 | 4 |
| FBXO3 | EVC2 | 0.750592 | 3 | 0 | 3 |
| FBXO3 | GPD1L | 0.750218 | 10 | 0 | 10 |
| FBXO3 | ACADM | 0.750137 | 10 | 0 | 10 |
| FBXO3 | MLKL | 0.749894 | 3 | 0 | 3 |
| FBXO3 | HBP1 | 0.748713 | 10 | 0 | 10 |
For details and further investigation, click here
