| Full name: dedicator of cytokinesis 9 | Alias Symbol: KIAA1058|ZIZ1 | ||
| Type: protein-coding gene | Cytoband: 13q32.3 | ||
| Entrez ID: 23348 | HGNC ID: HGNC:14132 | Ensembl Gene: ENSG00000088387 | OMIM ID: 607325 |
| Drug and gene relationship at DGIdb | |||
Expression of DOCK9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DOCK9 | 23348 | 212538_at | -1.2242 | 0.0294 | |
| GSE20347 | DOCK9 | 23348 | 212538_at | -1.6982 | 0.0000 | |
| GSE23400 | DOCK9 | 23348 | 212538_at | -1.3971 | 0.0000 | |
| GSE26886 | DOCK9 | 23348 | 212538_at | -1.7468 | 0.0000 | |
| GSE29001 | DOCK9 | 23348 | 212538_at | -1.4690 | 0.0002 | |
| GSE38129 | DOCK9 | 23348 | 212538_at | -1.3508 | 0.0000 | |
| GSE45670 | DOCK9 | 23348 | 212538_at | -0.5026 | 0.0044 | |
| GSE53622 | DOCK9 | 23348 | 54167 | -1.3097 | 0.0000 | |
| GSE53624 | DOCK9 | 23348 | 82390 | -1.8090 | 0.0000 | |
| GSE63941 | DOCK9 | 23348 | 212538_at | 1.0141 | 0.0551 | |
| GSE77861 | DOCK9 | 23348 | 212538_at | -1.3175 | 0.0008 | |
| GSE97050 | DOCK9 | A_21_P0012831 | -0.9147 | 0.0631 | ||
| SRP007169 | DOCK9 | 23348 | RNAseq | -1.7914 | 0.0000 | |
| SRP008496 | DOCK9 | 23348 | RNAseq | -1.6945 | 0.0000 | |
| SRP064894 | DOCK9 | 23348 | RNAseq | -1.5987 | 0.0000 | |
| SRP133303 | DOCK9 | 23348 | RNAseq | -1.3740 | 0.0000 | |
| SRP159526 | DOCK9 | 23348 | RNAseq | -1.7911 | 0.0001 | |
| SRP193095 | DOCK9 | 23348 | RNAseq | -1.5962 | 0.0000 | |
| SRP219564 | DOCK9 | 23348 | RNAseq | -1.0736 | 0.0281 | |
| TCGA | DOCK9 | 23348 | RNAseq | -0.0457 | 0.5083 |
Upregulated datasets: 0; Downregulated datasets: 16.
Survival by DOCK9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DOCK9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DOCK9 | 23348 | 4 | 8 | 18 | |
| GSE20123 | DOCK9 | 23348 | 4 | 8 | 18 | |
| GSE43470 | DOCK9 | 23348 | 4 | 12 | 27 | |
| GSE46452 | DOCK9 | 23348 | 0 | 32 | 27 | |
| GSE47630 | DOCK9 | 23348 | 3 | 26 | 11 | |
| GSE54993 | DOCK9 | 23348 | 11 | 4 | 55 | |
| GSE54994 | DOCK9 | 23348 | 3 | 16 | 34 | |
| GSE60625 | DOCK9 | 23348 | 0 | 3 | 8 | |
| GSE74703 | DOCK9 | 23348 | 3 | 10 | 23 | |
| GSE74704 | DOCK9 | 23348 | 2 | 7 | 11 | |
| TCGA | DOCK9 | 23348 | 14 | 35 | 47 |
Total number of gains: 48; Total number of losses: 161; Total Number of normals: 279.
Somatic mutations of DOCK9:
Generating mutation plots.
Highly correlated genes for DOCK9:
Showing top 20/1697 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DOCK9 | FCHO2 | 0.850752 | 7 | 0 | 7 |
| DOCK9 | CAST | 0.842041 | 11 | 0 | 11 |
| DOCK9 | SLC46A2 | 0.836443 | 7 | 0 | 7 |
| DOCK9 | VSIG10L | 0.83421 | 6 | 0 | 6 |
| DOCK9 | GYS2 | 0.833271 | 10 | 0 | 10 |
| DOCK9 | EVPL | 0.830376 | 10 | 0 | 10 |
| DOCK9 | GDPD3 | 0.830124 | 10 | 0 | 10 |
| DOCK9 | ACPP | 0.827926 | 10 | 0 | 10 |
| DOCK9 | RANBP9 | 0.826613 | 11 | 0 | 11 |
| DOCK9 | RMND5B | 0.825992 | 11 | 0 | 11 |
| DOCK9 | SCNN1B | 0.824577 | 10 | 0 | 10 |
| DOCK9 | A2ML1 | 0.818846 | 6 | 0 | 6 |
| DOCK9 | CYSRT1 | 0.817066 | 6 | 0 | 6 |
| DOCK9 | UPK1A | 0.816415 | 10 | 0 | 10 |
| DOCK9 | FAM214A | 0.816351 | 6 | 0 | 6 |
| DOCK9 | KAT2B | 0.814593 | 11 | 0 | 11 |
| DOCK9 | RSPH3 | 0.814337 | 4 | 0 | 4 |
| DOCK9 | EMP1 | 0.813578 | 10 | 0 | 10 |
| DOCK9 | ENDOU | 0.812991 | 11 | 0 | 11 |
| DOCK9 | C18orf25 | 0.812757 | 11 | 0 | 11 |
For details and further investigation, click here
