UGT2B11

 

Full name: UDP glucuronosyltransferase family 2 member B11 Alias Symbol: 
Type: protein-coding gene Cytoband: 4q13.2
Entrez ID: 10720 HGNC ID: HGNC:12545 Ensembl Gene: ENSG00000213759 OMIM ID: 603064
Drug and gene relationship at DGIdb

 

Expression of UGT2B11:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE53622 UGT2B11 10720 5189 -0.7975 0.0000
GSE53624 UGT2B11 10720 5189 -1.0417 0.0000
GSE97050 UGT2B11 A_21_P0012591 0.1129 0.6103

Upregulated datasets: 0; Downregulated datasets: 1.  

 

Survival by UGT2B11 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of UGT2B11:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 UGT2B11 10720 0 10 20
GSE20123 UGT2B11 10720 0 11 19
GSE43470 UGT2B11 10720 0 13 30
GSE46452 UGT2B11 10720 2 35 22
GSE47630 UGT2B11 10720 1 18 21
GSE54993 UGT2B11 10720 7 0 63
GSE54994 UGT2B11 10720 1 9 43
GSE60625 UGT2B11 10720 0 0 11
GSE74703 UGT2B11 10720 0 11 25
GSE74704 UGT2B11 10720 0 7 13
TCGA UGT2B11 10720 18 26 52

Total number of gains: 29; Total number of losses: 140; Total Number of normals: 319.  

 

Somatic mutations of UGT2B11:

 

Generating mutation plots.

 

Highly correlated genes for UGT2B11:

 

Showing all 11 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
UGT2B11CTSE0.765513303
UGT2B11PGC0.75899303
UGT2B11LRRC460.74882303
UGT2B11NUDT16L10.733217303
UGT2B11CHRNA100.726098303
UGT2B11REG3A0.710632303
UGT2B11ENTPD80.687959303
UGT2B11OR10G80.687865303
UGT2B11C4BPB0.605524303
UGT2B11KRT200.592124303
UGT2B11VSIG20.564309303

For details and further investigation, click here