| Full name: cholinergic receptor nicotinic alpha 10 subunit | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11p15.4 | ||
| Entrez ID: 57053 | HGNC ID: HGNC:13800 | Ensembl Gene: ENSG00000129749 | OMIM ID: 606372 |
| Drug and gene relationship at DGIdb | |||
Expression of CHRNA10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CHRNA10 | 57053 | 1568675_at | -0.0778 | 0.7281 | |
| GSE20347 | CHRNA10 | 57053 | 220210_at | -0.1635 | 0.0121 | |
| GSE23400 | CHRNA10 | 57053 | 220210_at | -0.0804 | 0.0129 | |
| GSE26886 | CHRNA10 | 57053 | 1568675_at | -0.1399 | 0.0899 | |
| GSE29001 | CHRNA10 | 57053 | 220210_at | -0.0073 | 0.9696 | |
| GSE38129 | CHRNA10 | 57053 | 220210_at | -0.1986 | 0.0060 | |
| GSE45670 | CHRNA10 | 57053 | 220210_at | 0.1744 | 0.1144 | |
| GSE53622 | CHRNA10 | 57053 | 79437 | -0.5052 | 0.0000 | |
| GSE53624 | CHRNA10 | 57053 | 79437 | -0.6279 | 0.0000 | |
| GSE63941 | CHRNA10 | 57053 | 1568675_at | 0.0541 | 0.7117 | |
| GSE77861 | CHRNA10 | 57053 | 1568675_at | -0.1484 | 0.1472 | |
| GSE97050 | CHRNA10 | 57053 | A_23_P411188 | -0.1281 | 0.5787 | |
| SRP133303 | CHRNA10 | 57053 | RNAseq | -0.6724 | 0.0825 | |
| SRP219564 | CHRNA10 | 57053 | RNAseq | -0.0170 | 0.9785 | |
| TCGA | CHRNA10 | 57053 | RNAseq | -0.5567 | 0.0135 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CHRNA10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CHRNA10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CHRNA10 | 57053 | 1 | 11 | 18 | |
| GSE20123 | CHRNA10 | 57053 | 1 | 11 | 18 | |
| GSE43470 | CHRNA10 | 57053 | 1 | 8 | 34 | |
| GSE46452 | CHRNA10 | 57053 | 7 | 8 | 44 | |
| GSE47630 | CHRNA10 | 57053 | 4 | 12 | 24 | |
| GSE54993 | CHRNA10 | 57053 | 3 | 1 | 66 | |
| GSE54994 | CHRNA10 | 57053 | 1 | 14 | 38 | |
| GSE60625 | CHRNA10 | 57053 | 0 | 0 | 11 | |
| GSE74703 | CHRNA10 | 57053 | 1 | 7 | 28 | |
| GSE74704 | CHRNA10 | 57053 | 0 | 7 | 13 | |
| TCGA | CHRNA10 | 57053 | 8 | 38 | 50 |
Total number of gains: 27; Total number of losses: 117; Total Number of normals: 344.
Somatic mutations of CHRNA10:
Generating mutation plots.
Highly correlated genes for CHRNA10:
Showing top 20/534 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CHRNA10 | LRRC46 | 0.76264 | 3 | 0 | 3 |
| CHRNA10 | NUDT16L1 | 0.753236 | 3 | 0 | 3 |
| CHRNA10 | BAHCC1 | 0.732196 | 3 | 0 | 3 |
| CHRNA10 | UGT2B11 | 0.726098 | 3 | 0 | 3 |
| CHRNA10 | FCN2 | 0.725804 | 4 | 0 | 4 |
| CHRNA10 | IQCD | 0.722737 | 3 | 0 | 3 |
| CHRNA10 | GATA4 | 0.721812 | 3 | 0 | 3 |
| CHRNA10 | ENTPD8 | 0.713897 | 3 | 0 | 3 |
| CHRNA10 | OR10G8 | 0.710433 | 3 | 0 | 3 |
| CHRNA10 | WDR78 | 0.6907 | 3 | 0 | 3 |
| CHRNA10 | RAX2 | 0.682332 | 3 | 0 | 3 |
| CHRNA10 | SPEF1 | 0.677401 | 4 | 0 | 3 |
| CHRNA10 | MYLK2 | 0.673446 | 4 | 0 | 3 |
| CHRNA10 | CACNA1A | 0.672212 | 3 | 0 | 3 |
| CHRNA10 | GPR182 | 0.663145 | 5 | 0 | 4 |
| CHRNA10 | CBLN4 | 0.662122 | 3 | 0 | 3 |
| CHRNA10 | MEPE | 0.659356 | 4 | 0 | 4 |
| CHRNA10 | ENGASE | 0.657355 | 4 | 0 | 3 |
| CHRNA10 | CCDC57 | 0.654632 | 5 | 0 | 5 |
| CHRNA10 | CLDN9 | 0.651909 | 6 | 0 | 5 |
For details and further investigation, click here
