| Full name: ectonucleoside triphosphate diphosphohydrolase 8 | Alias Symbol: UNQ2492|NTPDase-8 | ||
| Type: protein-coding gene | Cytoband: 9q34.3 | ||
| Entrez ID: 377841 | HGNC ID: HGNC:24860 | Ensembl Gene: ENSG00000188833 | OMIM ID: 616748 |
| Drug and gene relationship at DGIdb | |||
Expression of ENTPD8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | ENTPD8 | 377841 | 33358 | -0.5863 | 0.0000 | |
| GSE53624 | ENTPD8 | 377841 | 33358 | -0.7082 | 0.0000 | |
| GSE97050 | ENTPD8 | 377841 | A_33_P3420224 | -0.2623 | 0.3269 | |
| TCGA | ENTPD8 | 377841 | RNAseq | -2.6533 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ENTPD8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ENTPD8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ENTPD8 | 377841 | 5 | 7 | 18 | |
| GSE20123 | ENTPD8 | 377841 | 5 | 7 | 18 | |
| GSE43470 | ENTPD8 | 377841 | 3 | 7 | 33 | |
| GSE46452 | ENTPD8 | 377841 | 6 | 13 | 40 | |
| GSE47630 | ENTPD8 | 377841 | 6 | 15 | 19 | |
| GSE54993 | ENTPD8 | 377841 | 3 | 3 | 64 | |
| GSE54994 | ENTPD8 | 377841 | 19 | 3 | 31 | |
| GSE60625 | ENTPD8 | 377841 | 0 | 0 | 11 | |
| GSE74703 | ENTPD8 | 377841 | 3 | 5 | 28 | |
| GSE74704 | ENTPD8 | 377841 | 3 | 5 | 12 | |
| TCGA | ENTPD8 | 377841 | 30 | 23 | 43 |
Total number of gains: 83; Total number of losses: 88; Total Number of normals: 317.
Somatic mutations of ENTPD8:
Generating mutation plots.
Highly correlated genes for ENTPD8:
Showing top 20/44 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ENTPD8 | SCARA5 | 0.835961 | 3 | 0 | 3 |
| ENTPD8 | TMEM125 | 0.791576 | 3 | 0 | 3 |
| ENTPD8 | CLDN24 | 0.764143 | 3 | 0 | 3 |
| ENTPD8 | GDF7 | 0.760974 | 3 | 0 | 3 |
| ENTPD8 | TERT | 0.753218 | 3 | 0 | 3 |
| ENTPD8 | HTR3A | 0.75274 | 3 | 0 | 3 |
| ENTPD8 | MFSD6L | 0.751821 | 3 | 0 | 3 |
| ENTPD8 | NOXA1 | 0.748246 | 3 | 0 | 3 |
| ENTPD8 | LRRC46 | 0.74434 | 3 | 0 | 3 |
| ENTPD8 | TTC21A | 0.74391 | 3 | 0 | 3 |
| ENTPD8 | PHF21B | 0.742768 | 3 | 0 | 3 |
| ENTPD8 | TDGF1 | 0.7418 | 3 | 0 | 3 |
| ENTPD8 | AQP5 | 0.739232 | 3 | 0 | 3 |
| ENTPD8 | ZNF524 | 0.736299 | 3 | 0 | 3 |
| ENTPD8 | PKD2L1 | 0.732949 | 3 | 0 | 3 |
| ENTPD8 | RNF151 | 0.73289 | 3 | 0 | 3 |
| ENTPD8 | SP6 | 0.727875 | 3 | 0 | 3 |
| ENTPD8 | NUDT16L1 | 0.724487 | 3 | 0 | 3 |
| ENTPD8 | OR10G8 | 0.724388 | 3 | 0 | 3 |
| ENTPD8 | IL17RE | 0.721377 | 3 | 0 | 3 |
For details and further investigation, click here
