| Full name: regenerating family member 3 alpha | Alias Symbol: HIP|REG-III|REG3|PBCGF|PAP1 | ||
| Type: protein-coding gene | Cytoband: 2p12 | ||
| Entrez ID: 5068 | HGNC ID: HGNC:8601 | Ensembl Gene: ENSG00000172016 | OMIM ID: 167805 |
| Drug and gene relationship at DGIdb | |||
Expression of REG3A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | REG3A | 5068 | 234280_at | -0.0046 | 0.9893 | |
| GSE20347 | REG3A | 5068 | 205815_at | 0.0252 | 0.7566 | |
| GSE23400 | REG3A | 5068 | 205815_at | -0.0939 | 0.0428 | |
| GSE26886 | REG3A | 5068 | 234280_at | 0.2921 | 0.0193 | |
| GSE29001 | REG3A | 5068 | 205815_at | -0.1656 | 0.2420 | |
| GSE38129 | REG3A | 5068 | 205815_at | -0.3304 | 0.1580 | |
| GSE45670 | REG3A | 5068 | 234280_at | -0.1193 | 0.2187 | |
| GSE53622 | REG3A | 5068 | 75171 | -0.3711 | 0.0166 | |
| GSE53624 | REG3A | 5068 | 75171 | -0.6570 | 0.0000 | |
| GSE63941 | REG3A | 5068 | 234280_at | 0.1977 | 0.0814 | |
| GSE77861 | REG3A | 5068 | 234280_at | -0.0482 | 0.6421 | |
| GSE97050 | REG3A | 5068 | A_23_P119936 | -0.0013 | 0.9963 | |
| TCGA | REG3A | 5068 | RNAseq | -4.2882 | 0.0067 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by REG3A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of REG3A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | REG3A | 5068 | 9 | 2 | 19 | |
| GSE20123 | REG3A | 5068 | 8 | 2 | 20 | |
| GSE43470 | REG3A | 5068 | 4 | 0 | 39 | |
| GSE46452 | REG3A | 5068 | 2 | 3 | 54 | |
| GSE47630 | REG3A | 5068 | 7 | 0 | 33 | |
| GSE54993 | REG3A | 5068 | 0 | 6 | 64 | |
| GSE54994 | REG3A | 5068 | 10 | 0 | 43 | |
| GSE60625 | REG3A | 5068 | 0 | 3 | 8 | |
| GSE74703 | REG3A | 5068 | 4 | 0 | 32 | |
| GSE74704 | REG3A | 5068 | 5 | 1 | 14 | |
| TCGA | REG3A | 5068 | 36 | 3 | 57 |
Total number of gains: 85; Total number of losses: 20; Total Number of normals: 383.
Somatic mutations of REG3A:
Generating mutation plots.
Highly correlated genes for REG3A:
Showing top 20/815 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| REG3A | RIN1 | 0.811513 | 3 | 0 | 3 |
| REG3A | ISLR2 | 0.806796 | 4 | 0 | 4 |
| REG3A | CPAMD8 | 0.799827 | 3 | 0 | 3 |
| REG3A | LIM2 | 0.791823 | 4 | 0 | 4 |
| REG3A | STK32C | 0.782757 | 3 | 0 | 3 |
| REG3A | KRTAP19-1 | 0.776023 | 3 | 0 | 3 |
| REG3A | TM6SF2 | 0.765503 | 4 | 0 | 4 |
| REG3A | CCNJL | 0.760703 | 3 | 0 | 3 |
| REG3A | TUT1 | 0.753355 | 4 | 0 | 4 |
| REG3A | KIR3DL3 | 0.753117 | 4 | 0 | 3 |
| REG3A | TMEM101 | 0.751598 | 3 | 0 | 3 |
| REG3A | SLC5A5 | 0.749757 | 5 | 0 | 5 |
| REG3A | LRRC46 | 0.743926 | 5 | 0 | 5 |
| REG3A | RNF17 | 0.743489 | 4 | 0 | 4 |
| REG3A | SCN2B | 0.741625 | 4 | 0 | 4 |
| REG3A | MAPK15 | 0.740579 | 3 | 0 | 3 |
| REG3A | GPBAR1 | 0.73936 | 3 | 0 | 3 |
| REG3A | NPEPL1 | 0.736863 | 5 | 0 | 5 |
| REG3A | DOK7 | 0.734083 | 3 | 0 | 3 |
| REG3A | C19orf81 | 0.732255 | 3 | 0 | 3 |
For details and further investigation, click here
