| Full name: V-set and immunoglobulin domain containing 2 | Alias Symbol: CTXL|CTH | ||
| Type: protein-coding gene | Cytoband: 11q24.2 | ||
| Entrez ID: 23584 | HGNC ID: HGNC:17149 | Ensembl Gene: ENSG00000019102 | OMIM ID: 606011 |
| Drug and gene relationship at DGIdb | |||
Expression of VSIG2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | VSIG2 | 23584 | 228232_s_at | -1.1003 | 0.2056 | |
| GSE26886 | VSIG2 | 23584 | 229369_at | -1.8704 | 0.0000 | |
| GSE45670 | VSIG2 | 23584 | 228232_s_at | -1.5370 | 0.0001 | |
| GSE53622 | VSIG2 | 23584 | 30352 | -3.6825 | 0.0000 | |
| GSE53624 | VSIG2 | 23584 | 30352 | -4.1624 | 0.0000 | |
| GSE63941 | VSIG2 | 23584 | 229369_at | -0.0447 | 0.8523 | |
| GSE77861 | VSIG2 | 23584 | 228232_s_at | -0.9761 | 0.0008 | |
| GSE97050 | VSIG2 | 23584 | A_23_P36018 | -1.3702 | 0.1839 | |
| SRP007169 | VSIG2 | 23584 | RNAseq | -6.1910 | 0.0000 | |
| SRP008496 | VSIG2 | 23584 | RNAseq | -6.4285 | 0.0000 | |
| SRP064894 | VSIG2 | 23584 | RNAseq | -4.3669 | 0.0000 | |
| SRP133303 | VSIG2 | 23584 | RNAseq | -3.4224 | 0.0000 | |
| SRP159526 | VSIG2 | 23584 | RNAseq | -5.3037 | 0.0000 | |
| SRP193095 | VSIG2 | 23584 | RNAseq | -2.5229 | 0.0004 | |
| SRP219564 | VSIG2 | 23584 | RNAseq | -4.1910 | 0.0000 | |
| TCGA | VSIG2 | 23584 | RNAseq | -3.3909 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 12.
Survival by VSIG2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of VSIG2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VSIG2 | 23584 | 0 | 13 | 17 | |
| GSE20123 | VSIG2 | 23584 | 0 | 13 | 17 | |
| GSE43470 | VSIG2 | 23584 | 2 | 7 | 34 | |
| GSE46452 | VSIG2 | 23584 | 3 | 26 | 30 | |
| GSE47630 | VSIG2 | 23584 | 2 | 19 | 19 | |
| GSE54993 | VSIG2 | 23584 | 10 | 0 | 60 | |
| GSE54994 | VSIG2 | 23584 | 5 | 19 | 29 | |
| GSE60625 | VSIG2 | 23584 | 0 | 3 | 8 | |
| GSE74703 | VSIG2 | 23584 | 1 | 5 | 30 | |
| GSE74704 | VSIG2 | 23584 | 0 | 9 | 11 | |
| TCGA | VSIG2 | 23584 | 6 | 50 | 40 |
Total number of gains: 29; Total number of losses: 164; Total Number of normals: 295.
Somatic mutations of VSIG2:
Generating mutation plots.
Highly correlated genes for VSIG2:
Showing top 20/1699 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VSIG2 | UBL3 | 0.846058 | 7 | 0 | 7 |
| VSIG2 | C5orf66-AS1 | 0.843941 | 6 | 0 | 6 |
| VSIG2 | C18orf25 | 0.843262 | 6 | 0 | 6 |
| VSIG2 | UPK1A | 0.842698 | 7 | 0 | 7 |
| VSIG2 | C1orf116 | 0.841357 | 7 | 0 | 7 |
| VSIG2 | CHP1 | 0.83768 | 6 | 0 | 6 |
| VSIG2 | LPIN1 | 0.83724 | 6 | 0 | 6 |
| VSIG2 | CYP2J2 | 0.833222 | 7 | 0 | 7 |
| VSIG2 | NUCB2 | 0.832045 | 7 | 0 | 7 |
| VSIG2 | LMO7 | 0.827922 | 7 | 0 | 7 |
| VSIG2 | SMIM5 | 0.826663 | 6 | 0 | 6 |
| VSIG2 | GYS2 | 0.825315 | 6 | 0 | 6 |
| VSIG2 | PMM1 | 0.824272 | 7 | 0 | 7 |
| VSIG2 | IL12A | 0.823762 | 6 | 0 | 6 |
| VSIG2 | PADI1 | 0.821205 | 4 | 0 | 4 |
| VSIG2 | SMAGP | 0.821172 | 7 | 0 | 7 |
| VSIG2 | FNDC4 | 0.817942 | 7 | 0 | 7 |
| VSIG2 | NAGK | 0.816975 | 6 | 0 | 6 |
| VSIG2 | CAB39L | 0.816674 | 6 | 0 | 6 |
| VSIG2 | SPINK7 | 0.815975 | 7 | 0 | 7 |
For details and further investigation, click here
