| Full name: keratin 20 | Alias Symbol: CK20|K20|MGC35423 | ||
| Type: protein-coding gene | Cytoband: 17q21.2 | ||
| Entrez ID: 54474 | HGNC ID: HGNC:20412 | Ensembl Gene: ENSG00000171431 | OMIM ID: 608218 |
| Drug and gene relationship at DGIdb | |||
Expression of KRT20:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KRT20 | 54474 | 213953_at | -0.1115 | 0.6019 | |
| GSE20347 | KRT20 | 54474 | 213953_at | 0.1324 | 0.0250 | |
| GSE23400 | KRT20 | 54474 | 213953_at | -0.0994 | 0.3537 | |
| GSE26886 | KRT20 | 54474 | 213953_at | 0.1856 | 0.0698 | |
| GSE29001 | KRT20 | 54474 | 213953_at | -0.0767 | 0.5720 | |
| GSE38129 | KRT20 | 54474 | 213953_at | -0.1805 | 0.3866 | |
| GSE45670 | KRT20 | 54474 | 213953_at | 0.3164 | 0.4774 | |
| GSE53622 | KRT20 | 54474 | 5839 | -0.0736 | 0.8490 | |
| GSE53624 | KRT20 | 54474 | 5839 | -0.4050 | 0.1978 | |
| GSE63941 | KRT20 | 54474 | 213953_at | 0.2133 | 0.1173 | |
| GSE77861 | KRT20 | 54474 | 213953_at | 0.0341 | 0.8806 | |
| GSE97050 | KRT20 | 54474 | A_23_P66854 | 0.0783 | 0.6967 | |
| TCGA | KRT20 | 54474 | RNAseq | -4.3910 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by KRT20 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRT20:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRT20 | 54474 | 7 | 1 | 22 | |
| GSE20123 | KRT20 | 54474 | 7 | 1 | 22 | |
| GSE43470 | KRT20 | 54474 | 1 | 2 | 40 | |
| GSE46452 | KRT20 | 54474 | 34 | 0 | 25 | |
| GSE47630 | KRT20 | 54474 | 8 | 1 | 31 | |
| GSE54993 | KRT20 | 54474 | 3 | 4 | 63 | |
| GSE54994 | KRT20 | 54474 | 8 | 5 | 40 | |
| GSE60625 | KRT20 | 54474 | 4 | 0 | 7 | |
| GSE74703 | KRT20 | 54474 | 1 | 1 | 34 | |
| GSE74704 | KRT20 | 54474 | 5 | 1 | 14 | |
| TCGA | KRT20 | 54474 | 22 | 8 | 66 |
Total number of gains: 100; Total number of losses: 24; Total Number of normals: 364.
Somatic mutations of KRT20:
Generating mutation plots.
Highly correlated genes for KRT20:
Showing top 20/71 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRT20 | GKN1 | 0.786674 | 4 | 0 | 4 |
| KRT20 | GP9 | 0.713131 | 3 | 0 | 3 |
| KRT20 | SMIM6 | 0.681023 | 3 | 0 | 3 |
| KRT20 | PLA2G10 | 0.674898 | 3 | 0 | 3 |
| KRT20 | TFF2 | 0.672691 | 6 | 0 | 5 |
| KRT20 | MAPK15 | 0.672649 | 3 | 0 | 3 |
| KRT20 | BEND4 | 0.672595 | 3 | 0 | 3 |
| KRT20 | LY6H | 0.668667 | 3 | 0 | 3 |
| KRT20 | REG1A | 0.668352 | 5 | 0 | 4 |
| KRT20 | LGALS4 | 0.66427 | 5 | 0 | 4 |
| KRT20 | HAGHL | 0.661753 | 3 | 0 | 3 |
| KRT20 | WDR87 | 0.658084 | 3 | 0 | 3 |
| KRT20 | KCNJ13 | 0.657602 | 4 | 0 | 3 |
| KRT20 | PGC | 0.654969 | 6 | 0 | 5 |
| KRT20 | DOK7 | 0.654631 | 3 | 0 | 3 |
| KRT20 | STAC2 | 0.654052 | 3 | 0 | 3 |
| KRT20 | KRTAP3-1 | 0.65394 | 3 | 0 | 3 |
| KRT20 | C12orf42 | 0.644983 | 3 | 0 | 3 |
| KRT20 | TRPV6 | 0.643537 | 3 | 0 | 3 |
| KRT20 | NEUROD1 | 0.635865 | 5 | 0 | 4 |
For details and further investigation, click here
