| Full name: unc-80 homolog, NALCN channel complex subunit | Alias Symbol: FLJ33496|KIAA1843|UNC-80 | ||
| Type: protein-coding gene | Cytoband: 2q34 | ||
| Entrez ID: 285175 | HGNC ID: HGNC:26582 | Ensembl Gene: ENSG00000144406 | OMIM ID: 612636 |
Expression of UNC80:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UNC80 | 285175 | 243836_at | 0.0646 | 0.7753 | |
| GSE26886 | UNC80 | 285175 | 243836_at | 0.0601 | 0.4825 | |
| GSE45670 | UNC80 | 285175 | 243836_at | 0.1498 | 0.0462 | |
| GSE53622 | UNC80 | 285175 | 15498 | 0.1862 | 0.2986 | |
| GSE53624 | UNC80 | 285175 | 15498 | -0.3354 | 0.0059 | |
| GSE63941 | UNC80 | 285175 | 230220_at | 0.0932 | 0.7494 | |
| GSE77861 | UNC80 | 285175 | 243836_at | -0.0875 | 0.3541 | |
| GSE97050 | UNC80 | 285175 | A_33_P3410251 | -0.1134 | 0.6959 | |
| TCGA | UNC80 | 285175 | RNAseq | -2.1831 | 0.0020 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by UNC80 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UNC80:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UNC80 | 285175 | 2 | 12 | 16 | |
| GSE20123 | UNC80 | 285175 | 2 | 12 | 16 | |
| GSE43470 | UNC80 | 285175 | 1 | 6 | 36 | |
| GSE46452 | UNC80 | 285175 | 0 | 5 | 54 | |
| GSE47630 | UNC80 | 285175 | 4 | 5 | 31 | |
| GSE54993 | UNC80 | 285175 | 0 | 3 | 67 | |
| GSE54994 | UNC80 | 285175 | 9 | 9 | 35 | |
| GSE60625 | UNC80 | 285175 | 0 | 3 | 8 | |
| GSE74703 | UNC80 | 285175 | 1 | 5 | 30 | |
| GSE74704 | UNC80 | 285175 | 2 | 6 | 12 | |
| TCGA | UNC80 | 285175 | 12 | 24 | 60 |
Total number of gains: 33; Total number of losses: 90; Total Number of normals: 365.
Somatic mutations of UNC80:
Generating mutation plots.
Highly correlated genes for UNC80:
Showing all 15 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UNC80 | PDZK1 | 0.635816 | 3 | 0 | 3 |
| UNC80 | TRIM28 | 0.621807 | 3 | 0 | 3 |
| UNC80 | ABHD8 | 0.602633 | 4 | 0 | 3 |
| UNC80 | KRBA1 | 0.595288 | 3 | 0 | 3 |
| UNC80 | MGRN1 | 0.591242 | 3 | 0 | 3 |
| UNC80 | GPBAR1 | 0.586436 | 3 | 0 | 3 |
| UNC80 | TREML1 | 0.573068 | 3 | 0 | 3 |
| UNC80 | ANKRD34A | 0.564837 | 3 | 0 | 3 |
| UNC80 | CD3EAP | 0.561996 | 3 | 0 | 3 |
| UNC80 | OR1E1 | 0.545116 | 3 | 0 | 3 |
| UNC80 | TDP2 | 0.544811 | 3 | 0 | 3 |
| UNC80 | GATA1 | 0.544767 | 4 | 0 | 3 |
| UNC80 | ERCC2 | 0.540857 | 3 | 0 | 3 |
| UNC80 | DUS3L | 0.528551 | 3 | 0 | 3 |
| UNC80 | TRIAP1 | 0.511769 | 3 | 0 | 3 |
For details and further investigation, click here
