| Full name: dihydrouridine synthase 3 like | Alias Symbol: DUS3|FLJ13896 | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 56931 | HGNC ID: HGNC:26920 | Ensembl Gene: ENSG00000141994 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of DUS3L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DUS3L | 56931 | 224966_s_at | 0.4324 | 0.4093 | |
| GSE26886 | DUS3L | 56931 | 224966_s_at | 0.4807 | 0.0056 | |
| GSE45670 | DUS3L | 56931 | 224966_s_at | 0.0462 | 0.8294 | |
| GSE53622 | DUS3L | 56931 | 67340 | 0.2523 | 0.0059 | |
| GSE53624 | DUS3L | 56931 | 6160 | 0.4590 | 0.0000 | |
| GSE63941 | DUS3L | 56931 | 224966_s_at | 0.9122 | 0.0778 | |
| GSE77861 | DUS3L | 56931 | 224966_s_at | 0.2803 | 0.0418 | |
| GSE97050 | DUS3L | 56931 | A_33_P3344264 | 0.1252 | 0.7887 | |
| SRP007169 | DUS3L | 56931 | RNAseq | -0.2500 | 0.5553 | |
| SRP064894 | DUS3L | 56931 | RNAseq | 0.2025 | 0.3878 | |
| SRP133303 | DUS3L | 56931 | RNAseq | -0.0473 | 0.8316 | |
| SRP159526 | DUS3L | 56931 | RNAseq | 0.0099 | 0.9700 | |
| SRP193095 | DUS3L | 56931 | RNAseq | 0.4349 | 0.0000 | |
| SRP219564 | DUS3L | 56931 | RNAseq | 0.1740 | 0.4812 | |
| TCGA | DUS3L | 56931 | RNAseq | 0.1637 | 0.0119 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DUS3L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DUS3L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DUS3L | 56931 | 5 | 3 | 22 | |
| GSE20123 | DUS3L | 56931 | 4 | 2 | 24 | |
| GSE43470 | DUS3L | 56931 | 2 | 6 | 35 | |
| GSE46452 | DUS3L | 56931 | 47 | 1 | 11 | |
| GSE47630 | DUS3L | 56931 | 5 | 7 | 28 | |
| GSE54993 | DUS3L | 56931 | 16 | 3 | 51 | |
| GSE54994 | DUS3L | 56931 | 6 | 16 | 31 | |
| GSE60625 | DUS3L | 56931 | 9 | 0 | 2 | |
| GSE74703 | DUS3L | 56931 | 2 | 4 | 30 | |
| GSE74704 | DUS3L | 56931 | 1 | 2 | 17 | |
| TCGA | DUS3L | 56931 | 10 | 17 | 69 |
Total number of gains: 107; Total number of losses: 61; Total Number of normals: 320.
Somatic mutations of DUS3L:
Generating mutation plots.
Highly correlated genes for DUS3L:
Showing top 20/944 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DUS3L | ADO | 0.833701 | 3 | 0 | 3 |
| DUS3L | DDX23 | 0.808341 | 3 | 0 | 3 |
| DUS3L | HNRNPF | 0.80256 | 3 | 0 | 3 |
| DUS3L | TOR1A | 0.797542 | 3 | 0 | 3 |
| DUS3L | ATP6V0B | 0.791376 | 3 | 0 | 3 |
| DUS3L | ARHGAP19 | 0.784697 | 3 | 0 | 3 |
| DUS3L | RNF130 | 0.782466 | 3 | 0 | 3 |
| DUS3L | TRMT12 | 0.782034 | 3 | 0 | 3 |
| DUS3L | USP1 | 0.781209 | 3 | 0 | 3 |
| DUS3L | VMA21 | 0.778482 | 4 | 0 | 4 |
| DUS3L | DAZAP2 | 0.777455 | 3 | 0 | 3 |
| DUS3L | SMS | 0.771463 | 3 | 0 | 3 |
| DUS3L | PARVB | 0.77054 | 3 | 0 | 3 |
| DUS3L | MSH6 | 0.768447 | 4 | 0 | 4 |
| DUS3L | ORAI1 | 0.766289 | 3 | 0 | 3 |
| DUS3L | NIPA2 | 0.763276 | 3 | 0 | 3 |
| DUS3L | ZNF32 | 0.761912 | 3 | 0 | 3 |
| DUS3L | MED10 | 0.760938 | 3 | 0 | 3 |
| DUS3L | NUP205 | 0.760641 | 3 | 0 | 3 |
| DUS3L | TTC31 | 0.757841 | 3 | 0 | 3 |
For details and further investigation, click here
