| Full name: abhydrolase domain containing 8 | Alias Symbol: FLJ11743|MGC14280|MGC2512 | ||
| Type: protein-coding gene | Cytoband: 19p13.11 | ||
| Entrez ID: 79575 | HGNC ID: HGNC:23759 | Ensembl Gene: ENSG00000127220 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ABHD8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ABHD8 | 79575 | 219101_x_at | 0.3971 | 0.2732 | |
| GSE20347 | ABHD8 | 79575 | 219101_x_at | 0.2269 | 0.0201 | |
| GSE23400 | ABHD8 | 79575 | 219101_x_at | -0.0113 | 0.7568 | |
| GSE26886 | ABHD8 | 79575 | 219101_x_at | 0.2002 | 0.0677 | |
| GSE29001 | ABHD8 | 79575 | 219101_x_at | -0.0474 | 0.6452 | |
| GSE38129 | ABHD8 | 79575 | 219101_x_at | 0.1445 | 0.1796 | |
| GSE45670 | ABHD8 | 79575 | 219101_x_at | 0.0026 | 0.9852 | |
| GSE53622 | ABHD8 | 79575 | 67362 | 0.1865 | 0.0165 | |
| GSE53624 | ABHD8 | 79575 | 67362 | 0.5546 | 0.0000 | |
| GSE63941 | ABHD8 | 79575 | 219101_x_at | 0.7940 | 0.0841 | |
| GSE77861 | ABHD8 | 79575 | 219101_x_at | 0.0759 | 0.5533 | |
| GSE97050 | ABHD8 | 79575 | A_33_P3302165 | -0.1288 | 0.5722 | |
| SRP007169 | ABHD8 | 79575 | RNAseq | -0.4161 | 0.4177 | |
| SRP008496 | ABHD8 | 79575 | RNAseq | 0.4384 | 0.2854 | |
| SRP064894 | ABHD8 | 79575 | RNAseq | 0.9047 | 0.0062 | |
| SRP133303 | ABHD8 | 79575 | RNAseq | 0.0880 | 0.5799 | |
| SRP159526 | ABHD8 | 79575 | RNAseq | 0.7166 | 0.1491 | |
| SRP193095 | ABHD8 | 79575 | RNAseq | 0.3505 | 0.0189 | |
| SRP219564 | ABHD8 | 79575 | RNAseq | 0.2323 | 0.6508 | |
| TCGA | ABHD8 | 79575 | RNAseq | -0.0369 | 0.7019 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ABHD8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ABHD8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ABHD8 | 79575 | 4 | 4 | 22 | |
| GSE20123 | ABHD8 | 79575 | 3 | 2 | 25 | |
| GSE43470 | ABHD8 | 79575 | 2 | 6 | 35 | |
| GSE46452 | ABHD8 | 79575 | 47 | 1 | 11 | |
| GSE47630 | ABHD8 | 79575 | 4 | 8 | 28 | |
| GSE54993 | ABHD8 | 79575 | 15 | 4 | 51 | |
| GSE54994 | ABHD8 | 79575 | 6 | 14 | 33 | |
| GSE60625 | ABHD8 | 79575 | 9 | 0 | 2 | |
| GSE74703 | ABHD8 | 79575 | 2 | 4 | 30 | |
| GSE74704 | ABHD8 | 79575 | 0 | 2 | 18 | |
| TCGA | ABHD8 | 79575 | 17 | 9 | 70 |
Total number of gains: 109; Total number of losses: 54; Total Number of normals: 325.
Somatic mutations of ABHD8:
Generating mutation plots.
Highly correlated genes for ABHD8:
Showing top 20/387 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ABHD8 | ZNF579 | 0.752889 | 5 | 0 | 5 |
| ABHD8 | C2CD4B | 0.743212 | 3 | 0 | 3 |
| ABHD8 | NR1H2 | 0.729561 | 3 | 0 | 3 |
| ABHD8 | C7orf50 | 0.718357 | 3 | 0 | 3 |
| ABHD8 | E4F1 | 0.710577 | 3 | 0 | 3 |
| ABHD8 | ARID1A | 0.703015 | 3 | 0 | 3 |
| ABHD8 | DYNLL2 | 0.693341 | 3 | 0 | 3 |
| ABHD8 | PHC3 | 0.691007 | 3 | 0 | 3 |
| ABHD8 | MAP2K7 | 0.687369 | 5 | 0 | 4 |
| ABHD8 | AP2A2 | 0.686292 | 3 | 0 | 3 |
| ABHD8 | UBE2M | 0.674345 | 3 | 0 | 3 |
| ABHD8 | TBC1D25 | 0.671045 | 4 | 0 | 4 |
| ABHD8 | PNKP | 0.670863 | 3 | 0 | 3 |
| ABHD8 | MRPS14 | 0.664642 | 3 | 0 | 3 |
| ABHD8 | MYLIP | 0.663922 | 3 | 0 | 3 |
| ABHD8 | FZR1 | 0.662377 | 5 | 0 | 3 |
| ABHD8 | DNAH11 | 0.661924 | 4 | 0 | 3 |
| ABHD8 | NUDC | 0.660528 | 5 | 0 | 4 |
| ABHD8 | GDF9 | 0.660056 | 3 | 0 | 3 |
| ABHD8 | DDIT3 | 0.658883 | 3 | 0 | 3 |
For details and further investigation, click here
