| Full name: YY1 associated factor 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 12q12 | ||
| Entrez ID: 10138 | HGNC ID: HGNC:17363 | Ensembl Gene: ENSG00000015153 | OMIM ID: 607534 |
| Drug and gene relationship at DGIdb | |||
Expression of YAF2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | YAF2 | 10138 | 206238_s_at | -0.1689 | 0.4079 | |
| GSE20347 | YAF2 | 10138 | 206238_s_at | 0.1582 | 0.2616 | |
| GSE23400 | YAF2 | 10138 | 206238_s_at | 0.1141 | 0.0072 | |
| GSE26886 | YAF2 | 10138 | 206238_s_at | 0.0813 | 0.7158 | |
| GSE29001 | YAF2 | 10138 | 206238_s_at | 0.1518 | 0.4026 | |
| GSE38129 | YAF2 | 10138 | 206238_s_at | 0.2827 | 0.0634 | |
| GSE45670 | YAF2 | 10138 | 206238_s_at | -0.0970 | 0.3793 | |
| GSE53622 | YAF2 | 10138 | 50538 | 0.1010 | 0.2083 | |
| GSE53624 | YAF2 | 10138 | 50538 | 0.0794 | 0.2126 | |
| GSE63941 | YAF2 | 10138 | 206238_s_at | -0.0942 | 0.8285 | |
| GSE77861 | YAF2 | 10138 | 206238_s_at | 0.0407 | 0.8684 | |
| GSE97050 | YAF2 | 10138 | A_33_P3390456 | -0.1141 | 0.6126 | |
| SRP007169 | YAF2 | 10138 | RNAseq | 0.3547 | 0.4449 | |
| SRP008496 | YAF2 | 10138 | RNAseq | 0.2023 | 0.5101 | |
| SRP064894 | YAF2 | 10138 | RNAseq | 0.1069 | 0.5002 | |
| SRP133303 | YAF2 | 10138 | RNAseq | 0.0666 | 0.5639 | |
| SRP159526 | YAF2 | 10138 | RNAseq | 0.0681 | 0.7934 | |
| SRP193095 | YAF2 | 10138 | RNAseq | -0.0416 | 0.6378 | |
| SRP219564 | YAF2 | 10138 | RNAseq | -0.0146 | 0.9520 | |
| TCGA | YAF2 | 10138 | RNAseq | -0.0059 | 0.9191 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by YAF2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of YAF2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | YAF2 | 10138 | 4 | 1 | 25 | |
| GSE20123 | YAF2 | 10138 | 4 | 1 | 25 | |
| GSE43470 | YAF2 | 10138 | 3 | 4 | 36 | |
| GSE46452 | YAF2 | 10138 | 8 | 1 | 50 | |
| GSE47630 | YAF2 | 10138 | 11 | 2 | 27 | |
| GSE54993 | YAF2 | 10138 | 0 | 7 | 63 | |
| GSE54994 | YAF2 | 10138 | 6 | 2 | 45 | |
| GSE60625 | YAF2 | 10138 | 0 | 0 | 11 | |
| GSE74703 | YAF2 | 10138 | 3 | 2 | 31 | |
| GSE74704 | YAF2 | 10138 | 2 | 1 | 17 | |
| TCGA | YAF2 | 10138 | 17 | 12 | 67 |
Total number of gains: 58; Total number of losses: 33; Total Number of normals: 397.
Somatic mutations of YAF2:
Generating mutation plots.
Highly correlated genes for YAF2:
Showing top 20/65 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| YAF2 | TOM1L1 | 0.784191 | 3 | 0 | 3 |
| YAF2 | SLC30A4 | 0.741973 | 3 | 0 | 3 |
| YAF2 | ATP6V1G1 | 0.723849 | 3 | 0 | 3 |
| YAF2 | SYAP1 | 0.719218 | 3 | 0 | 3 |
| YAF2 | PNPLA8 | 0.718155 | 3 | 0 | 3 |
| YAF2 | ZFYVE16 | 0.709299 | 3 | 0 | 3 |
| YAF2 | ZFAND2A | 0.708928 | 3 | 0 | 3 |
| YAF2 | TADA2A | 0.702853 | 3 | 0 | 3 |
| YAF2 | GLUD2 | 0.698409 | 3 | 0 | 3 |
| YAF2 | RNF6 | 0.694897 | 3 | 0 | 3 |
| YAF2 | KALRN | 0.694254 | 3 | 0 | 3 |
| YAF2 | ZNF782 | 0.690513 | 3 | 0 | 3 |
| YAF2 | ZNF394 | 0.688449 | 4 | 0 | 4 |
| YAF2 | BCL10 | 0.686843 | 3 | 0 | 3 |
| YAF2 | KCNRG | 0.682482 | 3 | 0 | 3 |
| YAF2 | HNRNPUL2 | 0.681771 | 3 | 0 | 3 |
| YAF2 | TMEM127 | 0.679887 | 3 | 0 | 3 |
| YAF2 | RAB18 | 0.662543 | 3 | 0 | 3 |
| YAF2 | NRARP | 0.659378 | 3 | 0 | 3 |
| YAF2 | ATL2 | 0.654612 | 3 | 0 | 3 |
For details and further investigation, click here
