| Full name: ring finger protein 6 | Alias Symbol: DKFZp686P0776 | ||
| Type: protein-coding gene | Cytoband: 13q12.13 | ||
| Entrez ID: 6049 | HGNC ID: HGNC:10069 | Ensembl Gene: ENSG00000127870 | OMIM ID: 604242 |
| Drug and gene relationship at DGIdb | |||
Expression of RNF6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNF6 | 6049 | 203403_s_at | 0.0960 | 0.8973 | |
| GSE20347 | RNF6 | 6049 | 203403_s_at | -0.3161 | 0.0272 | |
| GSE23400 | RNF6 | 6049 | 203403_s_at | 0.1224 | 0.3775 | |
| GSE26886 | RNF6 | 6049 | 203403_s_at | 0.2701 | 0.3473 | |
| GSE29001 | RNF6 | 6049 | 203403_s_at | -0.2414 | 0.6425 | |
| GSE38129 | RNF6 | 6049 | 203403_s_at | -0.0712 | 0.6155 | |
| GSE45670 | RNF6 | 6049 | 203403_s_at | -0.0998 | 0.4745 | |
| GSE53622 | RNF6 | 6049 | 80164 | -0.2155 | 0.0045 | |
| GSE53624 | RNF6 | 6049 | 80164 | -0.3679 | 0.0000 | |
| GSE63941 | RNF6 | 6049 | 203403_s_at | -0.1155 | 0.7993 | |
| GSE77861 | RNF6 | 6049 | 203403_s_at | -0.0925 | 0.8231 | |
| GSE97050 | RNF6 | 6049 | A_23_P162734 | 0.0168 | 0.9672 | |
| SRP007169 | RNF6 | 6049 | RNAseq | -0.5937 | 0.0657 | |
| SRP008496 | RNF6 | 6049 | RNAseq | -0.3922 | 0.1087 | |
| SRP064894 | RNF6 | 6049 | RNAseq | -0.2561 | 0.3276 | |
| SRP133303 | RNF6 | 6049 | RNAseq | 0.0860 | 0.6122 | |
| SRP159526 | RNF6 | 6049 | RNAseq | -0.5459 | 0.1438 | |
| SRP193095 | RNF6 | 6049 | RNAseq | -0.4228 | 0.0001 | |
| SRP219564 | RNF6 | 6049 | RNAseq | -0.6821 | 0.0661 | |
| TCGA | RNF6 | 6049 | RNAseq | 0.0438 | 0.3690 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RNF6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RNF6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNF6 | 6049 | 1 | 13 | 16 | |
| GSE20123 | RNF6 | 6049 | 1 | 12 | 17 | |
| GSE43470 | RNF6 | 6049 | 2 | 12 | 29 | |
| GSE46452 | RNF6 | 6049 | 0 | 33 | 26 | |
| GSE47630 | RNF6 | 6049 | 3 | 26 | 11 | |
| GSE54993 | RNF6 | 6049 | 11 | 2 | 57 | |
| GSE54994 | RNF6 | 6049 | 1 | 13 | 39 | |
| GSE60625 | RNF6 | 6049 | 0 | 3 | 8 | |
| GSE74703 | RNF6 | 6049 | 2 | 9 | 25 | |
| GSE74704 | RNF6 | 6049 | 0 | 10 | 10 | |
| TCGA | RNF6 | 6049 | 6 | 44 | 46 |
Total number of gains: 27; Total number of losses: 177; Total Number of normals: 284.
Somatic mutations of RNF6:
Generating mutation plots.
Highly correlated genes for RNF6:
Showing top 20/673 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNF6 | RIPK3 | 0.788599 | 3 | 0 | 3 |
| RNF6 | NPAT | 0.775794 | 3 | 0 | 3 |
| RNF6 | TTC30B | 0.775 | 3 | 0 | 3 |
| RNF6 | SAMD12 | 0.758014 | 3 | 0 | 3 |
| RNF6 | TMEM167A | 0.750155 | 3 | 0 | 3 |
| RNF6 | EBPL | 0.746865 | 4 | 0 | 3 |
| RNF6 | SLC38A9 | 0.745082 | 4 | 0 | 4 |
| RNF6 | LACTB | 0.739289 | 3 | 0 | 3 |
| RNF6 | TBL2 | 0.732726 | 3 | 0 | 3 |
| RNF6 | RBM45 | 0.726 | 3 | 0 | 3 |
| RNF6 | C3orf38 | 0.72536 | 4 | 0 | 3 |
| RNF6 | ZNF649 | 0.713963 | 3 | 0 | 3 |
| RNF6 | MITD1 | 0.713758 | 4 | 0 | 3 |
| RNF6 | LYSMD3 | 0.709529 | 3 | 0 | 3 |
| RNF6 | MARVELD2 | 0.709008 | 4 | 0 | 4 |
| RNF6 | RNF135 | 0.705277 | 5 | 0 | 5 |
| RNF6 | DNAJC7 | 0.699213 | 4 | 0 | 3 |
| RNF6 | YAF2 | 0.694897 | 3 | 0 | 3 |
| RNF6 | ZNF273 | 0.692782 | 3 | 0 | 3 |
| RNF6 | BDP1 | 0.690533 | 4 | 0 | 4 |
For details and further investigation, click here
