| Full name: ATPase phospholipid transporting 8A2 | Alias Symbol: ATPIB|ML-1 | ||
| Type: protein-coding gene | Cytoband: 13q12.13 | ||
| Entrez ID: 51761 | HGNC ID: HGNC:13533 | Ensembl Gene: ENSG00000132932 | OMIM ID: 605870 |
| Drug and gene relationship at DGIdb | |||
Expression of ATP8A2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATP8A2 | 51761 | 219659_at | -0.0762 | 0.8835 | |
| GSE20347 | ATP8A2 | 51761 | 219659_at | 0.1463 | 0.4869 | |
| GSE23400 | ATP8A2 | 51761 | 219660_s_at | -0.0301 | 0.5357 | |
| GSE26886 | ATP8A2 | 51761 | 219659_at | 0.3455 | 0.0584 | |
| GSE29001 | ATP8A2 | 51761 | 219659_at | -0.1015 | 0.6737 | |
| GSE38129 | ATP8A2 | 51761 | 219659_at | 0.1760 | 0.3015 | |
| GSE45670 | ATP8A2 | 51761 | 219659_at | 0.0905 | 0.6131 | |
| GSE53622 | ATP8A2 | 51761 | 15959 | 0.7617 | 0.0000 | |
| GSE53624 | ATP8A2 | 51761 | 15959 | 0.6030 | 0.0005 | |
| GSE63941 | ATP8A2 | 51761 | 219659_at | 0.0891 | 0.7862 | |
| GSE77861 | ATP8A2 | 51761 | 231395_at | -0.0585 | 0.7150 | |
| GSE97050 | ATP8A2 | 51761 | A_33_P3286859 | -0.0280 | 0.9303 | |
| SRP133303 | ATP8A2 | 51761 | RNAseq | 0.5536 | 0.0948 | |
| SRP159526 | ATP8A2 | 51761 | RNAseq | 3.5790 | 0.0002 | |
| TCGA | ATP8A2 | 51761 | RNAseq | -1.2196 | 0.0177 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by ATP8A2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATP8A2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATP8A2 | 51761 | 1 | 12 | 17 | |
| GSE20123 | ATP8A2 | 51761 | 1 | 11 | 18 | |
| GSE43470 | ATP8A2 | 51761 | 2 | 12 | 29 | |
| GSE46452 | ATP8A2 | 51761 | 0 | 33 | 26 | |
| GSE47630 | ATP8A2 | 51761 | 3 | 26 | 11 | |
| GSE54993 | ATP8A2 | 51761 | 11 | 2 | 57 | |
| GSE54994 | ATP8A2 | 51761 | 1 | 13 | 39 | |
| GSE60625 | ATP8A2 | 51761 | 0 | 3 | 8 | |
| GSE74703 | ATP8A2 | 51761 | 2 | 9 | 25 | |
| GSE74704 | ATP8A2 | 51761 | 0 | 9 | 11 | |
| TCGA | ATP8A2 | 51761 | 5 | 46 | 45 |
Total number of gains: 26; Total number of losses: 176; Total Number of normals: 286.
Somatic mutations of ATP8A2:
Generating mutation plots.
Highly correlated genes for ATP8A2:
Showing top 20/239 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATP8A2 | CCDC8 | 0.749244 | 3 | 0 | 3 |
| ATP8A2 | C20orf85 | 0.747755 | 3 | 0 | 3 |
| ATP8A2 | FNDC9 | 0.742665 | 3 | 0 | 3 |
| ATP8A2 | ATP2B2 | 0.725509 | 4 | 0 | 4 |
| ATP8A2 | ENTPD1 | 0.709263 | 3 | 0 | 3 |
| ATP8A2 | LACRT | 0.708836 | 3 | 0 | 3 |
| ATP8A2 | TCTE1 | 0.68665 | 3 | 0 | 3 |
| ATP8A2 | DDIT4L | 0.68597 | 3 | 0 | 3 |
| ATP8A2 | FABP7 | 0.675825 | 5 | 0 | 4 |
| ATP8A2 | DEFB108B | 0.675521 | 3 | 0 | 3 |
| ATP8A2 | C10orf91 | 0.672386 | 3 | 0 | 3 |
| ATP8A2 | HECW1 | 0.671973 | 3 | 0 | 3 |
| ATP8A2 | TNFSF11 | 0.669207 | 4 | 0 | 3 |
| ATP8A2 | GH1 | 0.669158 | 3 | 0 | 3 |
| ATP8A2 | TNFRSF11B | 0.669155 | 7 | 0 | 5 |
| ATP8A2 | IQCF3 | 0.668194 | 3 | 0 | 3 |
| ATP8A2 | OPTC | 0.662415 | 4 | 0 | 3 |
| ATP8A2 | SULT1E1 | 0.661917 | 3 | 0 | 3 |
| ATP8A2 | CACNG4 | 0.661881 | 3 | 0 | 3 |
| ATP8A2 | DEFB121 | 0.661766 | 3 | 0 | 3 |
For details and further investigation, click here
