| Full name: chromosome transmission fidelity factor 18 | Alias Symbol: CHL12|C321D2.4|Ctf18 | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 63922 | HGNC ID: HGNC:18435 | Ensembl Gene: ENSG00000127586 | OMIM ID: 613201 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of CHTF18:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CHTF18 | 63922 | 226569_s_at | 1.1042 | 0.0208 | |
| GSE26886 | CHTF18 | 63922 | 226569_s_at | 0.7953 | 0.0000 | |
| GSE45670 | CHTF18 | 63922 | 226569_s_at | 0.8642 | 0.0001 | |
| GSE53622 | CHTF18 | 63922 | 73690 | 0.4968 | 0.0000 | |
| GSE53624 | CHTF18 | 63922 | 73690 | 0.5131 | 0.0000 | |
| GSE63941 | CHTF18 | 63922 | 226569_s_at | 0.7294 | 0.0245 | |
| GSE77861 | CHTF18 | 63922 | 226569_s_at | 0.2610 | 0.0631 | |
| GSE97050 | CHTF18 | 63922 | A_23_P354297 | 0.6426 | 0.4723 | |
| SRP007169 | CHTF18 | 63922 | RNAseq | 2.0888 | 0.0003 | |
| SRP064894 | CHTF18 | 63922 | RNAseq | 1.4746 | 0.0000 | |
| SRP133303 | CHTF18 | 63922 | RNAseq | 1.2359 | 0.0000 | |
| SRP159526 | CHTF18 | 63922 | RNAseq | 1.8325 | 0.0001 | |
| SRP193095 | CHTF18 | 63922 | RNAseq | 1.2348 | 0.0000 | |
| SRP219564 | CHTF18 | 63922 | RNAseq | 1.6111 | 0.0001 | |
| TCGA | CHTF18 | 63922 | RNAseq | 0.6598 | 0.0000 |
Upregulated datasets: 7; Downregulated datasets: 0.
Survival by CHTF18 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CHTF18:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CHTF18 | 63922 | 5 | 5 | 20 | |
| GSE20123 | CHTF18 | 63922 | 5 | 4 | 21 | |
| GSE43470 | CHTF18 | 63922 | 4 | 7 | 32 | |
| GSE46452 | CHTF18 | 63922 | 38 | 1 | 20 | |
| GSE47630 | CHTF18 | 63922 | 13 | 6 | 21 | |
| GSE54993 | CHTF18 | 63922 | 3 | 5 | 62 | |
| GSE54994 | CHTF18 | 63922 | 5 | 9 | 39 | |
| GSE60625 | CHTF18 | 63922 | 4 | 0 | 7 | |
| GSE74703 | CHTF18 | 63922 | 4 | 5 | 27 | |
| GSE74704 | CHTF18 | 63922 | 3 | 2 | 15 | |
| TCGA | CHTF18 | 63922 | 20 | 14 | 62 |
Total number of gains: 104; Total number of losses: 58; Total Number of normals: 326.
Somatic mutations of CHTF18:
Generating mutation plots.
Highly correlated genes for CHTF18:
Showing top 20/1070 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CHTF18 | MTERF3 | 0.75903 | 3 | 0 | 3 |
| CHTF18 | METTL1 | 0.754674 | 4 | 0 | 4 |
| CHTF18 | BCAR1 | 0.748878 | 5 | 0 | 5 |
| CHTF18 | ZXDC | 0.742684 | 3 | 0 | 3 |
| CHTF18 | CBS | 0.732767 | 3 | 0 | 3 |
| CHTF18 | UMPS | 0.730586 | 5 | 0 | 4 |
| CHTF18 | DROSHA | 0.726536 | 3 | 0 | 3 |
| CHTF18 | MYBL2 | 0.721078 | 8 | 0 | 7 |
| CHTF18 | CMSS1 | 0.721037 | 5 | 0 | 4 |
| CHTF18 | ECE2 | 0.715836 | 5 | 0 | 5 |
| CHTF18 | SPRED3 | 0.715796 | 3 | 0 | 3 |
| CHTF18 | NETO2 | 0.713017 | 5 | 0 | 5 |
| CHTF18 | SLC19A1 | 0.709834 | 3 | 0 | 3 |
| CHTF18 | KNOP1 | 0.707182 | 5 | 0 | 5 |
| CHTF18 | PGP | 0.706634 | 8 | 0 | 8 |
| CHTF18 | NUDT1 | 0.706163 | 6 | 0 | 6 |
| CHTF18 | CDC45 | 0.706149 | 6 | 0 | 6 |
| CHTF18 | MEX3D | 0.701465 | 5 | 0 | 4 |
| CHTF18 | LYRM4 | 0.7014 | 3 | 0 | 3 |
| CHTF18 | AMPD2 | 0.700111 | 3 | 0 | 3 |
For details and further investigation, click here
