| Full name: zinc finger protein 586 | Alias Symbol: FLJ20070 | ||
| Type: protein-coding gene | Cytoband: 19q13.43 | ||
| Entrez ID: 54807 | HGNC ID: HGNC:25949 | Ensembl Gene: ENSG00000083828 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF586:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF586 | 54807 | 219711_at | -0.1428 | 0.7288 | |
| GSE20347 | ZNF586 | 54807 | 219711_at | -0.3813 | 0.0247 | |
| GSE23400 | ZNF586 | 54807 | 219711_at | -0.0739 | 0.2582 | |
| GSE26886 | ZNF586 | 54807 | 219711_at | -0.2445 | 0.1808 | |
| GSE29001 | ZNF586 | 54807 | 219711_at | -0.4396 | 0.2295 | |
| GSE38129 | ZNF586 | 54807 | 219711_at | -0.3405 | 0.0087 | |
| GSE45670 | ZNF586 | 54807 | 219711_at | -0.4417 | 0.0320 | |
| GSE53622 | ZNF586 | 54807 | 107009 | -0.3014 | 0.0002 | |
| GSE53624 | ZNF586 | 54807 | 107009 | -0.3406 | 0.0000 | |
| GSE63941 | ZNF586 | 54807 | 219711_at | 0.1381 | 0.8555 | |
| GSE77861 | ZNF586 | 54807 | 219711_at | 0.2522 | 0.1607 | |
| GSE97050 | ZNF586 | 54807 | A_23_P107693 | -0.1959 | 0.4014 | |
| SRP007169 | ZNF586 | 54807 | RNAseq | -0.7726 | 0.0618 | |
| SRP008496 | ZNF586 | 54807 | RNAseq | -0.6881 | 0.0313 | |
| SRP064894 | ZNF586 | 54807 | RNAseq | -0.5014 | 0.0023 | |
| SRP133303 | ZNF586 | 54807 | RNAseq | -0.2082 | 0.4577 | |
| SRP159526 | ZNF586 | 54807 | RNAseq | -0.2974 | 0.5259 | |
| SRP193095 | ZNF586 | 54807 | RNAseq | -0.5626 | 0.0000 | |
| SRP219564 | ZNF586 | 54807 | RNAseq | -0.4785 | 0.3105 | |
| TCGA | ZNF586 | 54807 | RNAseq | -0.1888 | 0.0256 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNF586 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF586:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF586 | 54807 | 2 | 4 | 24 | |
| GSE20123 | ZNF586 | 54807 | 2 | 3 | 25 | |
| GSE43470 | ZNF586 | 54807 | 3 | 9 | 31 | |
| GSE46452 | ZNF586 | 54807 | 45 | 1 | 13 | |
| GSE47630 | ZNF586 | 54807 | 8 | 6 | 26 | |
| GSE54993 | ZNF586 | 54807 | 18 | 4 | 48 | |
| GSE54994 | ZNF586 | 54807 | 5 | 12 | 36 | |
| GSE60625 | ZNF586 | 54807 | 9 | 0 | 2 | |
| GSE74703 | ZNF586 | 54807 | 3 | 6 | 27 | |
| GSE74704 | ZNF586 | 54807 | 2 | 1 | 17 | |
| TCGA | ZNF586 | 54807 | 19 | 15 | 62 |
Total number of gains: 116; Total number of losses: 61; Total Number of normals: 311.
Somatic mutations of ZNF586:
Generating mutation plots.
Highly correlated genes for ZNF586:
Showing top 20/173 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF586 | ZNF383 | 0.772823 | 3 | 0 | 3 |
| ZNF586 | DMTF1 | 0.769476 | 3 | 0 | 3 |
| ZNF586 | ARID2 | 0.762152 | 3 | 0 | 3 |
| ZNF586 | REV1 | 0.743477 | 3 | 0 | 3 |
| ZNF586 | MTRF1 | 0.743423 | 3 | 0 | 3 |
| ZNF586 | SLC25A28 | 0.737731 | 3 | 0 | 3 |
| ZNF586 | ZNF805 | 0.737021 | 3 | 0 | 3 |
| ZNF586 | ZNF829 | 0.731885 | 3 | 0 | 3 |
| ZNF586 | HDDC2 | 0.725139 | 3 | 0 | 3 |
| ZNF586 | THOC2 | 0.717176 | 3 | 0 | 3 |
| ZNF586 | MCCC1 | 0.714425 | 3 | 0 | 3 |
| ZNF586 | SCAF8 | 0.713192 | 3 | 0 | 3 |
| ZNF586 | ZFP3 | 0.712998 | 3 | 0 | 3 |
| ZNF586 | ZNF506 | 0.707518 | 4 | 0 | 4 |
| ZNF586 | RWDD1 | 0.700152 | 3 | 0 | 3 |
| ZNF586 | MOB4 | 0.700006 | 4 | 0 | 3 |
| ZNF586 | TAS2R4 | 0.699302 | 3 | 0 | 3 |
| ZNF586 | NAPB | 0.698915 | 3 | 0 | 3 |
| ZNF586 | ZNF322 | 0.696685 | 3 | 0 | 3 |
| ZNF586 | FMR1 | 0.684622 | 3 | 0 | 3 |
For details and further investigation, click here
