| Full name: solute carrier family 25 member 28 | Alias Symbol: MRS3/4|MRS4L | ||
| Type: protein-coding gene | Cytoband: 10q24.2 | ||
| Entrez ID: 81894 | HGNC ID: HGNC:23472 | Ensembl Gene: ENSG00000155287 | OMIM ID: 609767 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of SLC25A28:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC25A28 | 81894 | 223192_at | 0.2742 | 0.5110 | |
| GSE20347 | SLC25A28 | 81894 | 221432_s_at | -0.0072 | 0.9608 | |
| GSE23400 | SLC25A28 | 81894 | 221432_s_at | 0.2216 | 0.0008 | |
| GSE26886 | SLC25A28 | 81894 | 223192_at | 0.5226 | 0.0219 | |
| GSE29001 | SLC25A28 | 81894 | 221432_s_at | 0.1755 | 0.5713 | |
| GSE38129 | SLC25A28 | 81894 | 221432_s_at | 0.0448 | 0.7010 | |
| GSE45670 | SLC25A28 | 81894 | 223192_at | 0.2279 | 0.1619 | |
| GSE53622 | SLC25A28 | 81894 | 68476 | 0.1461 | 0.0177 | |
| GSE53624 | SLC25A28 | 81894 | 68476 | 0.2119 | 0.0001 | |
| GSE63941 | SLC25A28 | 81894 | 223192_at | -0.3733 | 0.4180 | |
| GSE77861 | SLC25A28 | 81894 | 223192_at | 0.1249 | 0.4800 | |
| GSE97050 | SLC25A28 | 81894 | A_23_P75220 | 0.1437 | 0.5714 | |
| SRP007169 | SLC25A28 | 81894 | RNAseq | -0.0256 | 0.9540 | |
| SRP008496 | SLC25A28 | 81894 | RNAseq | 0.5266 | 0.0905 | |
| SRP064894 | SLC25A28 | 81894 | RNAseq | 0.3104 | 0.1053 | |
| SRP133303 | SLC25A28 | 81894 | RNAseq | 0.1174 | 0.4990 | |
| SRP159526 | SLC25A28 | 81894 | RNAseq | -0.2590 | 0.4223 | |
| SRP193095 | SLC25A28 | 81894 | RNAseq | 0.4701 | 0.0001 | |
| SRP219564 | SLC25A28 | 81894 | RNAseq | 0.1178 | 0.6401 | |
| TCGA | SLC25A28 | 81894 | RNAseq | 0.0973 | 0.0997 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SLC25A28 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC25A28:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC25A28 | 81894 | 1 | 8 | 21 | |
| GSE20123 | SLC25A28 | 81894 | 1 | 7 | 22 | |
| GSE43470 | SLC25A28 | 81894 | 0 | 7 | 36 | |
| GSE46452 | SLC25A28 | 81894 | 0 | 11 | 48 | |
| GSE47630 | SLC25A28 | 81894 | 2 | 14 | 24 | |
| GSE54993 | SLC25A28 | 81894 | 8 | 0 | 62 | |
| GSE54994 | SLC25A28 | 81894 | 1 | 12 | 40 | |
| GSE60625 | SLC25A28 | 81894 | 0 | 0 | 11 | |
| GSE74703 | SLC25A28 | 81894 | 0 | 5 | 31 | |
| GSE74704 | SLC25A28 | 81894 | 0 | 4 | 16 | |
| TCGA | SLC25A28 | 81894 | 5 | 28 | 63 |
Total number of gains: 18; Total number of losses: 96; Total Number of normals: 374.
Somatic mutations of SLC25A28:
Generating mutation plots.
Highly correlated genes for SLC25A28:
Showing top 20/341 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC25A28 | C1orf35 | 0.798355 | 3 | 0 | 3 |
| SLC25A28 | VGLL4 | 0.792895 | 3 | 0 | 3 |
| SLC25A28 | SF1 | 0.774042 | 3 | 0 | 3 |
| SLC25A28 | SURF6 | 0.76642 | 3 | 0 | 3 |
| SLC25A28 | ZNF791 | 0.762186 | 3 | 0 | 3 |
| SLC25A28 | GATAD2B | 0.760353 | 3 | 0 | 3 |
| SLC25A28 | SLC25A29 | 0.75466 | 3 | 0 | 3 |
| SLC25A28 | ZNF121 | 0.749282 | 3 | 0 | 3 |
| SLC25A28 | TERF1 | 0.747001 | 3 | 0 | 3 |
| SLC25A28 | PDHA1 | 0.742482 | 3 | 0 | 3 |
| SLC25A28 | CIC | 0.740651 | 3 | 0 | 3 |
| SLC25A28 | ZNF586 | 0.737731 | 3 | 0 | 3 |
| SLC25A28 | HAUS7 | 0.737005 | 3 | 0 | 3 |
| SLC25A28 | MED26 | 0.736955 | 3 | 0 | 3 |
| SLC25A28 | MAP3K2 | 0.735486 | 3 | 0 | 3 |
| SLC25A28 | MYH3 | 0.731595 | 3 | 0 | 3 |
| SLC25A28 | BAG6 | 0.730776 | 3 | 0 | 3 |
| SLC25A28 | NOP58 | 0.729129 | 3 | 0 | 3 |
| SLC25A28 | MRPS21 | 0.727341 | 3 | 0 | 3 |
| SLC25A28 | RNASEH2B | 0.720955 | 4 | 0 | 3 |
For details and further investigation, click here
