| Full name: SR-related CTD associated factor 8 | Alias Symbol: KIAA1116 | ||
| Type: protein-coding gene | Cytoband: 6q25.2 | ||
| Entrez ID: 22828 | HGNC ID: HGNC:20959 | Ensembl Gene: ENSG00000213079 | OMIM ID: 616024 |
| Drug and gene relationship at DGIdb | |||
Expression of SCAF8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SCAF8 | 22828 | 203250_at | -0.0812 | 0.9124 | |
| GSE20347 | SCAF8 | 22828 | 203250_at | 0.0256 | 0.8894 | |
| GSE23400 | SCAF8 | 22828 | 203250_at | 0.1838 | 0.0172 | |
| GSE26886 | SCAF8 | 22828 | 203250_at | -0.2626 | 0.2878 | |
| GSE29001 | SCAF8 | 22828 | 203250_at | 0.1435 | 0.4328 | |
| GSE38129 | SCAF8 | 22828 | 203250_at | 0.0690 | 0.5204 | |
| GSE45670 | SCAF8 | 22828 | 203250_at | -0.2737 | 0.0047 | |
| GSE53622 | SCAF8 | 22828 | 165435 | -0.2610 | 0.0000 | |
| GSE53624 | SCAF8 | 22828 | 165435 | -0.1683 | 0.0004 | |
| GSE63941 | SCAF8 | 22828 | 203250_at | -0.9038 | 0.0075 | |
| GSE77861 | SCAF8 | 22828 | 203250_at | 0.0090 | 0.9741 | |
| GSE97050 | SCAF8 | 22828 | A_23_P111303 | -0.1453 | 0.5409 | |
| SRP007169 | SCAF8 | 22828 | RNAseq | 1.2930 | 0.0012 | |
| SRP008496 | SCAF8 | 22828 | RNAseq | 1.3526 | 0.0002 | |
| SRP064894 | SCAF8 | 22828 | RNAseq | -0.2349 | 0.2608 | |
| SRP133303 | SCAF8 | 22828 | RNAseq | 0.0954 | 0.2957 | |
| SRP159526 | SCAF8 | 22828 | RNAseq | -0.0143 | 0.9371 | |
| SRP193095 | SCAF8 | 22828 | RNAseq | 0.0146 | 0.8146 | |
| SRP219564 | SCAF8 | 22828 | RNAseq | -0.0569 | 0.8539 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by SCAF8 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of SCAF8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SCAF8 | 22828 | 1 | 4 | 25 | |
| GSE20123 | SCAF8 | 22828 | 1 | 3 | 26 | |
| GSE43470 | SCAF8 | 22828 | 4 | 0 | 39 | |
| GSE46452 | SCAF8 | 22828 | 3 | 10 | 46 | |
| GSE47630 | SCAF8 | 22828 | 9 | 4 | 27 | |
| GSE54993 | SCAF8 | 22828 | 3 | 2 | 65 | |
| GSE54994 | SCAF8 | 22828 | 8 | 8 | 37 | |
| GSE60625 | SCAF8 | 22828 | 0 | 1 | 10 | |
| GSE74703 | SCAF8 | 22828 | 4 | 0 | 32 | |
| GSE74704 | SCAF8 | 22828 | 0 | 1 | 19 | |
| TCGA | SCAF8 | 22828 | 12 | 21 | 63 |
Total number of gains: 45; Total number of losses: 54; Total Number of normals: 389.
Somatic mutations of SCAF8:
Generating mutation plots.
Highly correlated genes for SCAF8:
Showing top 20/520 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SCAF8 | LUC7L2 | 0.830329 | 3 | 0 | 3 |
| SCAF8 | BRAP | 0.8217 | 3 | 0 | 3 |
| SCAF8 | ZNF578 | 0.80899 | 3 | 0 | 3 |
| SCAF8 | ZBTB2 | 0.799296 | 3 | 0 | 3 |
| SCAF8 | SIPA1L2 | 0.793142 | 3 | 0 | 3 |
| SCAF8 | RBM4 | 0.785463 | 3 | 0 | 3 |
| SCAF8 | LMBRD2 | 0.784202 | 3 | 0 | 3 |
| SCAF8 | ARL6 | 0.764861 | 3 | 0 | 3 |
| SCAF8 | FNIP2 | 0.764406 | 3 | 0 | 3 |
| SCAF8 | RRAGB | 0.763449 | 3 | 0 | 3 |
| SCAF8 | SLC25A14 | 0.761376 | 3 | 0 | 3 |
| SCAF8 | RSAD1 | 0.760359 | 3 | 0 | 3 |
| SCAF8 | TTC14 | 0.757346 | 3 | 0 | 3 |
| SCAF8 | RAD17 | 0.755915 | 3 | 0 | 3 |
| SCAF8 | KCTD18 | 0.754191 | 3 | 0 | 3 |
| SCAF8 | ARHGAP31 | 0.749732 | 3 | 0 | 3 |
| SCAF8 | TADA2A | 0.746308 | 3 | 0 | 3 |
| SCAF8 | TTC23 | 0.741043 | 3 | 0 | 3 |
| SCAF8 | IP6K1 | 0.73704 | 3 | 0 | 3 |
| SCAF8 | ZNF514 | 0.727499 | 3 | 0 | 3 |
For details and further investigation, click here
