| Full name: REV1 DNA directed polymerase | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2q11.2 | ||
| Entrez ID: 51455 | HGNC ID: HGNC:14060 | Ensembl Gene: ENSG00000135945 | OMIM ID: 606134 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of REV1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | REV1 | 51455 | 222628_s_at | -0.0376 | 0.9538 | |
| GSE20347 | REV1 | 51455 | 218428_s_at | -0.0457 | 0.8192 | |
| GSE23400 | REV1 | 51455 | 218428_s_at | -0.0645 | 0.4018 | |
| GSE26886 | REV1 | 51455 | 218428_s_at | 0.0338 | 0.9097 | |
| GSE29001 | REV1 | 51455 | 218428_s_at | -0.2269 | 0.3988 | |
| GSE38129 | REV1 | 51455 | 218428_s_at | 0.0696 | 0.6232 | |
| GSE45670 | REV1 | 51455 | 218428_s_at | -0.0406 | 0.8361 | |
| GSE53622 | REV1 | 51455 | 15057 | -0.4403 | 0.0000 | |
| GSE53624 | REV1 | 51455 | 15057 | -0.4145 | 0.0000 | |
| GSE63941 | REV1 | 51455 | 218428_s_at | 0.5578 | 0.1884 | |
| GSE77861 | REV1 | 51455 | 222628_s_at | 0.2443 | 0.1449 | |
| GSE97050 | REV1 | 51455 | A_24_P291426 | -0.3852 | 0.1858 | |
| SRP007169 | REV1 | 51455 | RNAseq | 0.0093 | 0.9804 | |
| SRP008496 | REV1 | 51455 | RNAseq | 0.0876 | 0.7048 | |
| SRP064894 | REV1 | 51455 | RNAseq | -0.4664 | 0.0549 | |
| SRP133303 | REV1 | 51455 | RNAseq | -0.0215 | 0.8859 | |
| SRP159526 | REV1 | 51455 | RNAseq | -0.2848 | 0.2290 | |
| SRP193095 | REV1 | 51455 | RNAseq | -0.3582 | 0.0002 | |
| SRP219564 | REV1 | 51455 | RNAseq | -0.6353 | 0.0208 | |
| TCGA | REV1 | 51455 | RNAseq | 0.0095 | 0.8488 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by REV1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of REV1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | REV1 | 51455 | 6 | 2 | 22 | |
| GSE20123 | REV1 | 51455 | 6 | 2 | 22 | |
| GSE43470 | REV1 | 51455 | 3 | 1 | 39 | |
| GSE46452 | REV1 | 51455 | 2 | 3 | 54 | |
| GSE47630 | REV1 | 51455 | 7 | 0 | 33 | |
| GSE54993 | REV1 | 51455 | 0 | 6 | 64 | |
| GSE54994 | REV1 | 51455 | 10 | 0 | 43 | |
| GSE60625 | REV1 | 51455 | 0 | 3 | 8 | |
| GSE74703 | REV1 | 51455 | 3 | 1 | 32 | |
| GSE74704 | REV1 | 51455 | 4 | 1 | 15 | |
| TCGA | REV1 | 51455 | 34 | 5 | 57 |
Total number of gains: 75; Total number of losses: 24; Total Number of normals: 389.
Somatic mutations of REV1:
Generating mutation plots.
Highly correlated genes for REV1:
Showing top 20/182 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| REV1 | DNAJC7 | 0.757495 | 3 | 0 | 3 |
| REV1 | ZNF503 | 0.746257 | 3 | 0 | 3 |
| REV1 | ZNF586 | 0.743477 | 3 | 0 | 3 |
| REV1 | IFT74 | 0.742924 | 3 | 0 | 3 |
| REV1 | CHD1 | 0.742307 | 3 | 0 | 3 |
| REV1 | CORO1C | 0.735048 | 3 | 0 | 3 |
| REV1 | PIK3CA | 0.732879 | 3 | 0 | 3 |
| REV1 | SUCLG1 | 0.724384 | 3 | 0 | 3 |
| REV1 | KIAA1257 | 0.721483 | 3 | 0 | 3 |
| REV1 | HAUS2 | 0.710469 | 3 | 0 | 3 |
| REV1 | OSGEP | 0.70727 | 3 | 0 | 3 |
| REV1 | RPS6KB1 | 0.70023 | 4 | 0 | 4 |
| REV1 | ZNF317 | 0.698061 | 3 | 0 | 3 |
| REV1 | TPP2 | 0.696383 | 3 | 0 | 3 |
| REV1 | CPPED1 | 0.691369 | 4 | 0 | 3 |
| REV1 | ZNF830 | 0.689983 | 3 | 0 | 3 |
| REV1 | NUCKS1 | 0.679484 | 4 | 0 | 3 |
| REV1 | IGIP | 0.678581 | 3 | 0 | 3 |
| REV1 | CCNC | 0.673821 | 5 | 0 | 4 |
| REV1 | MRPS28 | 0.671865 | 3 | 0 | 3 |
For details and further investigation, click here
