| Full name: HD domain containing 2 | Alias Symbol: CGI-130|dJ167O5.2 | ||
| Type: protein-coding gene | Cytoband: 6q22.31 | ||
| Entrez ID: 51020 | HGNC ID: HGNC:21078 | Ensembl Gene: ENSG00000111906 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of HDDC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HDDC2 | 51020 | 203259_s_at | -0.0401 | 0.9138 | |
| GSE20347 | HDDC2 | 51020 | 203259_s_at | -0.0985 | 0.5988 | |
| GSE23400 | HDDC2 | 51020 | 203259_s_at | 0.2525 | 0.0013 | |
| GSE26886 | HDDC2 | 51020 | 203259_s_at | 0.5819 | 0.0026 | |
| GSE29001 | HDDC2 | 51020 | 203259_s_at | -0.0754 | 0.8115 | |
| GSE38129 | HDDC2 | 51020 | 203259_s_at | -0.0066 | 0.9659 | |
| GSE45670 | HDDC2 | 51020 | 203259_s_at | -0.1028 | 0.4421 | |
| GSE53622 | HDDC2 | 51020 | 120415 | 0.0630 | 0.2551 | |
| GSE53624 | HDDC2 | 51020 | 120415 | -0.1058 | 0.0831 | |
| GSE63941 | HDDC2 | 51020 | 203259_s_at | -0.7625 | 0.0871 | |
| GSE77861 | HDDC2 | 51020 | 203259_s_at | 0.0493 | 0.9128 | |
| GSE97050 | HDDC2 | 51020 | A_33_P3212650 | 0.2564 | 0.3074 | |
| SRP007169 | HDDC2 | 51020 | RNAseq | -0.3712 | 0.3163 | |
| SRP008496 | HDDC2 | 51020 | RNAseq | -0.4525 | 0.0446 | |
| SRP064894 | HDDC2 | 51020 | RNAseq | -0.0069 | 0.9734 | |
| SRP133303 | HDDC2 | 51020 | RNAseq | -0.1480 | 0.3053 | |
| SRP159526 | HDDC2 | 51020 | RNAseq | 0.0996 | 0.5674 | |
| SRP193095 | HDDC2 | 51020 | RNAseq | -0.4525 | 0.0010 | |
| SRP219564 | HDDC2 | 51020 | RNAseq | -0.0775 | 0.7089 | |
| TCGA | HDDC2 | 51020 | RNAseq | 0.0174 | 0.8029 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HDDC2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HDDC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HDDC2 | 51020 | 2 | 4 | 24 | |
| GSE20123 | HDDC2 | 51020 | 3 | 3 | 24 | |
| GSE43470 | HDDC2 | 51020 | 5 | 0 | 38 | |
| GSE46452 | HDDC2 | 51020 | 2 | 11 | 46 | |
| GSE47630 | HDDC2 | 51020 | 9 | 4 | 27 | |
| GSE54993 | HDDC2 | 51020 | 3 | 3 | 64 | |
| GSE54994 | HDDC2 | 51020 | 8 | 9 | 36 | |
| GSE60625 | HDDC2 | 51020 | 0 | 1 | 10 | |
| GSE74703 | HDDC2 | 51020 | 4 | 0 | 32 | |
| GSE74704 | HDDC2 | 51020 | 0 | 1 | 19 | |
| TCGA | HDDC2 | 51020 | 12 | 18 | 66 |
Total number of gains: 48; Total number of losses: 54; Total Number of normals: 386.
Somatic mutations of HDDC2:
Generating mutation plots.
Highly correlated genes for HDDC2:
Showing top 20/196 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HDDC2 | GDAP2 | 0.725212 | 3 | 0 | 3 |
| HDDC2 | ZNF586 | 0.725139 | 3 | 0 | 3 |
| HDDC2 | SLC25A32 | 0.721178 | 3 | 0 | 3 |
| HDDC2 | TCTEX1D2 | 0.719046 | 3 | 0 | 3 |
| HDDC2 | TCEA1 | 0.713493 | 3 | 0 | 3 |
| HDDC2 | SEL1L3 | 0.710328 | 3 | 0 | 3 |
| HDDC2 | INTS4 | 0.703474 | 3 | 0 | 3 |
| HDDC2 | LRRC58 | 0.702015 | 3 | 0 | 3 |
| HDDC2 | DMTF1 | 0.700673 | 3 | 0 | 3 |
| HDDC2 | RSF1 | 0.697141 | 3 | 0 | 3 |
| HDDC2 | FBXO28 | 0.694843 | 4 | 0 | 4 |
| HDDC2 | RBM41 | 0.686994 | 3 | 0 | 3 |
| HDDC2 | FKTN | 0.685032 | 4 | 0 | 4 |
| HDDC2 | MRPS9 | 0.684638 | 3 | 0 | 3 |
| HDDC2 | BAG4 | 0.680109 | 3 | 0 | 3 |
| HDDC2 | ZNF251 | 0.673463 | 3 | 0 | 3 |
| HDDC2 | CLPP | 0.672735 | 3 | 0 | 3 |
| HDDC2 | EIF1AX | 0.671935 | 4 | 0 | 3 |
| HDDC2 | NOL10 | 0.670243 | 3 | 0 | 3 |
| HDDC2 | RNF217 | 0.66432 | 4 | 0 | 3 |
For details and further investigation, click here
