| Full name: MOB family member 4, phocein | Alias Symbol: MOB3|DKFZP564M112|CGI-95|2C4D|PHOCN | ||
| Type: protein-coding gene | Cytoband: 2q33.1 | ||
| Entrez ID: 25843 | HGNC ID: HGNC:17261 | Ensembl Gene: ENSG00000115540 | OMIM ID: 609361 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of MOB4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MOB4 | 25843 | 202919_at | -0.6483 | 0.0265 | |
| GSE20347 | MOB4 | 25843 | 202919_at | -0.7225 | 0.0000 | |
| GSE23400 | MOB4 | 25843 | 202919_at | -0.4918 | 0.0000 | |
| GSE26886 | MOB4 | 25843 | 202919_at | -0.7007 | 0.0007 | |
| GSE29001 | MOB4 | 25843 | 202919_at | -0.5171 | 0.1744 | |
| GSE38129 | MOB4 | 25843 | 202919_at | -0.5133 | 0.0004 | |
| GSE45670 | MOB4 | 25843 | 202919_at | -0.5314 | 0.0002 | |
| GSE53622 | MOB4 | 25843 | 86978 | -0.6934 | 0.0000 | |
| GSE53624 | MOB4 | 25843 | 86978 | -0.7444 | 0.0000 | |
| GSE63941 | MOB4 | 25843 | 202919_at | -0.3560 | 0.4470 | |
| GSE77861 | MOB4 | 25843 | 202919_at | -0.2217 | 0.2494 | |
| GSE97050 | MOB4 | 25843 | A_23_P210274 | -0.4298 | 0.2082 | |
| SRP007169 | MOB4 | 25843 | RNAseq | -1.2568 | 0.0007 | |
| SRP008496 | MOB4 | 25843 | RNAseq | -1.1662 | 0.0000 | |
| SRP064894 | MOB4 | 25843 | RNAseq | -0.7722 | 0.0196 | |
| SRP133303 | MOB4 | 25843 | RNAseq | -0.2674 | 0.1022 | |
| SRP159526 | MOB4 | 25843 | RNAseq | -0.8845 | 0.0009 | |
| SRP193095 | MOB4 | 25843 | RNAseq | -0.7752 | 0.0000 | |
| SRP219564 | MOB4 | 25843 | RNAseq | -0.9099 | 0.0088 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by MOB4 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of MOB4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MOB4 | 25843 | 10 | 2 | 18 | |
| GSE20123 | MOB4 | 25843 | 10 | 2 | 18 | |
| GSE43470 | MOB4 | 25843 | 3 | 1 | 39 | |
| GSE46452 | MOB4 | 25843 | 1 | 4 | 54 | |
| GSE47630 | MOB4 | 25843 | 4 | 5 | 31 | |
| GSE54993 | MOB4 | 25843 | 0 | 3 | 67 | |
| GSE54994 | MOB4 | 25843 | 11 | 8 | 34 | |
| GSE60625 | MOB4 | 25843 | 0 | 3 | 8 | |
| GSE74703 | MOB4 | 25843 | 2 | 1 | 33 | |
| GSE74704 | MOB4 | 25843 | 5 | 2 | 13 | |
| TCGA | MOB4 | 25843 | 22 | 9 | 65 |
Total number of gains: 68; Total number of losses: 40; Total Number of normals: 380.
Somatic mutations of MOB4:
Generating mutation plots.
Highly correlated genes for MOB4:
Showing top 20/1395 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MOB4 | ZRANB1 | 0.802209 | 3 | 0 | 3 |
| MOB4 | EXOC6B | 0.788485 | 3 | 0 | 3 |
| MOB4 | ABHD3 | 0.763686 | 3 | 0 | 3 |
| MOB4 | SEC22B | 0.756405 | 4 | 0 | 3 |
| MOB4 | FBXO3 | 0.754916 | 10 | 0 | 10 |
| MOB4 | APOB | 0.752127 | 3 | 0 | 3 |
| MOB4 | GDAP2 | 0.750354 | 3 | 0 | 3 |
| MOB4 | UBE2D2 | 0.749829 | 3 | 0 | 3 |
| MOB4 | ARHGAP31 | 0.749274 | 3 | 0 | 3 |
| MOB4 | SGMS1 | 0.737985 | 3 | 0 | 3 |
| MOB4 | TNFRSF19 | 0.733701 | 3 | 0 | 3 |
| MOB4 | KIF21A | 0.7307 | 4 | 0 | 4 |
| MOB4 | ZNF407 | 0.729974 | 3 | 0 | 3 |
| MOB4 | KIAA1191 | 0.728261 | 5 | 0 | 4 |
| MOB4 | UBQLN1 | 0.72749 | 3 | 0 | 3 |
| MOB4 | UAP1 | 0.723278 | 3 | 0 | 3 |
| MOB4 | CCDC7 | 0.72208 | 3 | 0 | 3 |
| MOB4 | ALG14 | 0.718138 | 3 | 0 | 3 |
| MOB4 | KDM3A | 0.715212 | 4 | 0 | 3 |
| MOB4 | MAML3 | 0.714291 | 3 | 0 | 3 |
For details and further investigation, click here
