| Full name: fragile X mental retardation 1 | Alias Symbol: FMRP|FRAXA|MGC87458 | ||
| Type: protein-coding gene | Cytoband: Xq27.3 | ||
| Entrez ID: 2332 | HGNC ID: HGNC:3775 | Ensembl Gene: ENSG00000102081 | OMIM ID: 309550 |
| Drug and gene relationship at DGIdb | |||
Expression of FMR1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FMR1 | 2332 | 215245_x_at | -0.0251 | 0.9518 | |
| GSE20347 | FMR1 | 2332 | 215245_x_at | 0.2083 | 0.1666 | |
| GSE23400 | FMR1 | 2332 | 215245_x_at | 0.3951 | 0.0001 | |
| GSE26886 | FMR1 | 2332 | 215245_x_at | 1.0571 | 0.0000 | |
| GSE29001 | FMR1 | 2332 | 215245_x_at | 0.2733 | 0.4653 | |
| GSE38129 | FMR1 | 2332 | 215245_x_at | 0.1306 | 0.2719 | |
| GSE45670 | FMR1 | 2332 | 215245_x_at | 0.1708 | 0.3201 | |
| GSE53622 | FMR1 | 2332 | 20533 | 0.1836 | 0.0020 | |
| GSE53624 | FMR1 | 2332 | 122586 | 0.1340 | 0.0482 | |
| GSE63941 | FMR1 | 2332 | 215245_x_at | 0.2758 | 0.6009 | |
| GSE77861 | FMR1 | 2332 | 215245_x_at | 0.1901 | 0.4060 | |
| GSE97050 | FMR1 | 2332 | A_24_P93967 | 0.0503 | 0.8473 | |
| SRP007169 | FMR1 | 2332 | RNAseq | 0.9467 | 0.0683 | |
| SRP008496 | FMR1 | 2332 | RNAseq | 0.9272 | 0.0018 | |
| SRP064894 | FMR1 | 2332 | RNAseq | -0.0268 | 0.8938 | |
| SRP133303 | FMR1 | 2332 | RNAseq | 0.5957 | 0.0131 | |
| SRP159526 | FMR1 | 2332 | RNAseq | 0.0001 | 0.9997 | |
| SRP193095 | FMR1 | 2332 | RNAseq | 0.0046 | 0.9556 | |
| SRP219564 | FMR1 | 2332 | RNAseq | -0.0312 | 0.9237 | |
| TCGA | FMR1 | 2332 | RNAseq | 0.1201 | 0.0195 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by FMR1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FMR1:
No record found for this gene.
Somatic mutations of FMR1:
Generating mutation plots.
Highly correlated genes for FMR1:
Showing top 20/788 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FMR1 | RPS6KA3 | 0.853717 | 3 | 0 | 3 |
| FMR1 | MNAT1 | 0.81255 | 3 | 0 | 3 |
| FMR1 | TIMM9 | 0.808525 | 3 | 0 | 3 |
| FMR1 | NOL10 | 0.798939 | 3 | 0 | 3 |
| FMR1 | NOL9 | 0.798436 | 3 | 0 | 3 |
| FMR1 | ZNF700 | 0.784166 | 3 | 0 | 3 |
| FMR1 | KIAA1324L | 0.764878 | 3 | 0 | 3 |
| FMR1 | CCNH | 0.763652 | 3 | 0 | 3 |
| FMR1 | CMC1 | 0.761319 | 3 | 0 | 3 |
| FMR1 | RPS19BP1 | 0.756463 | 3 | 0 | 3 |
| FMR1 | CDC42SE2 | 0.755729 | 4 | 0 | 4 |
| FMR1 | GSTO1 | 0.75419 | 3 | 0 | 3 |
| FMR1 | FNDC3A | 0.749958 | 4 | 0 | 3 |
| FMR1 | COMMD3 | 0.746107 | 3 | 0 | 3 |
| FMR1 | RNASEH1 | 0.742108 | 3 | 0 | 3 |
| FMR1 | LIPT1 | 0.741079 | 4 | 0 | 4 |
| FMR1 | CKAP5 | 0.73781 | 3 | 0 | 3 |
| FMR1 | ATP11C | 0.735721 | 6 | 0 | 6 |
| FMR1 | GTF3C2 | 0.73365 | 3 | 0 | 3 |
| FMR1 | ZNF558 | 0.733254 | 3 | 0 | 3 |
For details and further investigation, click here
