| Full name: zona pellucida glycoprotein 4 | Alias Symbol: ZPB | ||
| Type: protein-coding gene | Cytoband: 1q43 | ||
| Entrez ID: 57829 | HGNC ID: HGNC:15770 | Ensembl Gene: ENSG00000116996 | OMIM ID: 613514 |
| Drug and gene relationship at DGIdb | |||
Expression of ZP4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZP4 | 57829 | 231756_at | -0.0366 | 0.9089 | |
| GSE26886 | ZP4 | 57829 | 231756_at | 0.1338 | 0.1591 | |
| GSE45670 | ZP4 | 57829 | 231756_at | 0.2000 | 0.0739 | |
| GSE53622 | ZP4 | 57829 | 25100 | 1.2662 | 0.0000 | |
| GSE53624 | ZP4 | 57829 | 25100 | 0.0614 | 0.7773 | |
| GSE63941 | ZP4 | 57829 | 231756_at | 0.0590 | 0.7222 | |
| GSE77861 | ZP4 | 57829 | 231756_at | -0.0290 | 0.8599 | |
| TCGA | ZP4 | 57829 | RNAseq | 3.9263 | 0.0253 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by ZP4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZP4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZP4 | 57829 | 9 | 1 | 20 | |
| GSE20123 | ZP4 | 57829 | 9 | 1 | 20 | |
| GSE43470 | ZP4 | 57829 | 8 | 1 | 34 | |
| GSE46452 | ZP4 | 57829 | 4 | 2 | 53 | |
| GSE47630 | ZP4 | 57829 | 15 | 0 | 25 | |
| GSE54993 | ZP4 | 57829 | 0 | 6 | 64 | |
| GSE54994 | ZP4 | 57829 | 16 | 0 | 37 | |
| GSE60625 | ZP4 | 57829 | 0 | 0 | 11 | |
| GSE74703 | ZP4 | 57829 | 8 | 1 | 27 | |
| GSE74704 | ZP4 | 57829 | 3 | 0 | 17 | |
| TCGA | ZP4 | 57829 | 43 | 4 | 49 |
Total number of gains: 115; Total number of losses: 16; Total Number of normals: 357.
Somatic mutations of ZP4:
Generating mutation plots.
Highly correlated genes for ZP4:
Showing all 13 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZP4 | FAM66D | 0.625458 | 3 | 0 | 3 |
| ZP4 | HCCAT5 | 0.621034 | 3 | 0 | 3 |
| ZP4 | PIP5KL1 | 0.596661 | 4 | 0 | 3 |
| ZP4 | NKAIN1 | 0.584072 | 3 | 0 | 3 |
| ZP4 | PFDN1 | 0.559293 | 3 | 0 | 3 |
| ZP4 | RGMB-AS1 | 0.557387 | 4 | 0 | 4 |
| ZP4 | POU3F1 | 0.550915 | 5 | 0 | 3 |
| ZP4 | CELA1 | 0.547846 | 4 | 0 | 3 |
| ZP4 | GJB3 | 0.54504 | 3 | 0 | 3 |
| ZP4 | ODF3L2 | 0.542765 | 3 | 0 | 3 |
| ZP4 | MIR31HG | 0.534528 | 3 | 0 | 3 |
| ZP4 | OR10J1 | 0.529641 | 3 | 0 | 3 |
| ZP4 | CNIH2 | 0.511615 | 4 | 0 | 3 |
For details and further investigation, click here
