| Full name: prefoldin subunit 1 | Alias Symbol: PFD1 | ||
| Type: protein-coding gene | Cytoband: 5q31.3 | ||
| Entrez ID: 5201 | HGNC ID: HGNC:8866 | Ensembl Gene: ENSG00000113068 | OMIM ID: 604897 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PFDN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PFDN1 | 5201 | 201507_at | -0.2128 | 0.5183 | |
| GSE20347 | PFDN1 | 5201 | 201507_at | -0.1226 | 0.2553 | |
| GSE23400 | PFDN1 | 5201 | 201507_at | 0.0030 | 0.9540 | |
| GSE26886 | PFDN1 | 5201 | 201507_at | 0.2351 | 0.1339 | |
| GSE29001 | PFDN1 | 5201 | 201507_at | -0.1135 | 0.3481 | |
| GSE38129 | PFDN1 | 5201 | 201507_at | -0.2361 | 0.0080 | |
| GSE45670 | PFDN1 | 5201 | 201507_at | -0.1064 | 0.3714 | |
| GSE53622 | PFDN1 | 5201 | 43935 | -0.1874 | 0.0009 | |
| GSE53624 | PFDN1 | 5201 | 43935 | -0.1944 | 0.0000 | |
| GSE63941 | PFDN1 | 5201 | 201507_at | 0.2115 | 0.5050 | |
| GSE77861 | PFDN1 | 5201 | 201507_at | -0.1678 | 0.4750 | |
| GSE97050 | PFDN1 | 5201 | A_23_P70020 | -0.0901 | 0.7509 | |
| SRP007169 | PFDN1 | 5201 | RNAseq | -0.8697 | 0.0198 | |
| SRP008496 | PFDN1 | 5201 | RNAseq | -0.8547 | 0.0000 | |
| SRP064894 | PFDN1 | 5201 | RNAseq | -0.0477 | 0.7792 | |
| SRP133303 | PFDN1 | 5201 | RNAseq | 0.4275 | 0.0358 | |
| SRP159526 | PFDN1 | 5201 | RNAseq | -0.2655 | 0.3472 | |
| SRP193095 | PFDN1 | 5201 | RNAseq | -0.3359 | 0.0002 | |
| SRP219564 | PFDN1 | 5201 | RNAseq | -0.2844 | 0.2436 | |
| TCGA | PFDN1 | 5201 | RNAseq | 0.0490 | 0.3358 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PFDN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PFDN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PFDN1 | 5201 | 3 | 11 | 16 | |
| GSE20123 | PFDN1 | 5201 | 4 | 11 | 15 | |
| GSE43470 | PFDN1 | 5201 | 4 | 8 | 31 | |
| GSE46452 | PFDN1 | 5201 | 0 | 27 | 32 | |
| GSE47630 | PFDN1 | 5201 | 0 | 20 | 20 | |
| GSE54993 | PFDN1 | 5201 | 9 | 1 | 60 | |
| GSE54994 | PFDN1 | 5201 | 2 | 14 | 37 | |
| GSE60625 | PFDN1 | 5201 | 0 | 0 | 11 | |
| GSE74703 | PFDN1 | 5201 | 3 | 6 | 27 | |
| GSE74704 | PFDN1 | 5201 | 3 | 5 | 12 | |
| TCGA | PFDN1 | 5201 | 4 | 37 | 55 |
Total number of gains: 32; Total number of losses: 140; Total Number of normals: 316.
Somatic mutations of PFDN1:
Generating mutation plots.
Highly correlated genes for PFDN1:
Showing top 20/227 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PFDN1 | CCNH | 0.789278 | 3 | 0 | 3 |
| PFDN1 | OGG1 | 0.785042 | 3 | 0 | 3 |
| PFDN1 | NSRP1 | 0.779347 | 3 | 0 | 3 |
| PFDN1 | USP32 | 0.767374 | 3 | 0 | 3 |
| PFDN1 | MAN2B2 | 0.752111 | 3 | 0 | 3 |
| PFDN1 | LMF2 | 0.725773 | 3 | 0 | 3 |
| PFDN1 | NAGA | 0.719496 | 3 | 0 | 3 |
| PFDN1 | ST6GALNAC6 | 0.714921 | 4 | 0 | 3 |
| PFDN1 | GATA5 | 0.710569 | 3 | 0 | 3 |
| PFDN1 | HHLA1 | 0.709318 | 3 | 0 | 3 |
| PFDN1 | TMEM214 | 0.707322 | 3 | 0 | 3 |
| PFDN1 | GSK3A | 0.706289 | 5 | 0 | 3 |
| PFDN1 | NFAM1 | 0.703801 | 3 | 0 | 3 |
| PFDN1 | RAB27A | 0.703665 | 3 | 0 | 3 |
| PFDN1 | PFKFB3 | 0.701234 | 3 | 0 | 3 |
| PFDN1 | PI16 | 0.69973 | 3 | 0 | 3 |
| PFDN1 | MTMR11 | 0.692507 | 3 | 0 | 3 |
| PFDN1 | HKDC1 | 0.689577 | 3 | 0 | 3 |
| PFDN1 | ROPN1 | 0.684771 | 3 | 0 | 3 |
| PFDN1 | WDFY3 | 0.683148 | 3 | 0 | 3 |
For details and further investigation, click here
