| Full name: phosphatidylinositol-4-phosphate 5-kinase like 1 | Alias Symbol: bA203J24.5|MGC46424 | ||
| Type: protein-coding gene | Cytoband: 9q34.11 | ||
| Entrez ID: 138429 | HGNC ID: HGNC:28711 | Ensembl Gene: ENSG00000167103 | OMIM ID: 612865 |
| Drug and gene relationship at DGIdb | |||
Expression of PIP5KL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PIP5KL1 | 138429 | 243116_at | 0.0557 | 0.8615 | |
| GSE26886 | PIP5KL1 | 138429 | 243116_at | 0.4419 | 0.0017 | |
| GSE45670 | PIP5KL1 | 138429 | 243116_at | 0.1816 | 0.2052 | |
| GSE53622 | PIP5KL1 | 138429 | 52150 | -0.6377 | 0.0000 | |
| GSE53624 | PIP5KL1 | 138429 | 52150 | -0.1870 | 0.0274 | |
| GSE63941 | PIP5KL1 | 138429 | 243116_at | 0.2415 | 0.3577 | |
| GSE77861 | PIP5KL1 | 138429 | 243116_at | 0.0151 | 0.9391 | |
| GSE97050 | PIP5KL1 | 138429 | A_33_P3235262 | 0.0619 | 0.8107 | |
| SRP007169 | PIP5KL1 | 138429 | RNAseq | -0.1429 | 0.8558 | |
| SRP064894 | PIP5KL1 | 138429 | RNAseq | 0.4193 | 0.0949 | |
| SRP133303 | PIP5KL1 | 138429 | RNAseq | -0.3881 | 0.3089 | |
| SRP159526 | PIP5KL1 | 138429 | RNAseq | 0.8833 | 0.0865 | |
| SRP193095 | PIP5KL1 | 138429 | RNAseq | 0.4118 | 0.0922 | |
| SRP219564 | PIP5KL1 | 138429 | RNAseq | -1.7389 | 0.0020 | |
| TCGA | PIP5KL1 | 138429 | RNAseq | 0.6629 | 0.0047 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PIP5KL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PIP5KL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PIP5KL1 | 138429 | 6 | 9 | 15 | |
| GSE20123 | PIP5KL1 | 138429 | 6 | 9 | 15 | |
| GSE43470 | PIP5KL1 | 138429 | 5 | 7 | 31 | |
| GSE46452 | PIP5KL1 | 138429 | 6 | 13 | 40 | |
| GSE47630 | PIP5KL1 | 138429 | 3 | 16 | 21 | |
| GSE54993 | PIP5KL1 | 138429 | 3 | 3 | 64 | |
| GSE54994 | PIP5KL1 | 138429 | 11 | 8 | 34 | |
| GSE60625 | PIP5KL1 | 138429 | 0 | 0 | 11 | |
| GSE74703 | PIP5KL1 | 138429 | 5 | 5 | 26 | |
| GSE74704 | PIP5KL1 | 138429 | 3 | 7 | 10 | |
| TCGA | PIP5KL1 | 138429 | 27 | 25 | 44 |
Total number of gains: 75; Total number of losses: 102; Total Number of normals: 311.
Somatic mutations of PIP5KL1:
Generating mutation plots.
Highly correlated genes for PIP5KL1:
Showing top 20/183 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PIP5KL1 | PRG3 | 0.800061 | 3 | 0 | 3 |
| PIP5KL1 | GPR150 | 0.783736 | 3 | 0 | 3 |
| PIP5KL1 | RTBDN | 0.777714 | 3 | 0 | 3 |
| PIP5KL1 | GH1 | 0.759935 | 3 | 0 | 3 |
| PIP5KL1 | HGD | 0.744685 | 3 | 0 | 3 |
| PIP5KL1 | CDRT15 | 0.743052 | 3 | 0 | 3 |
| PIP5KL1 | GRM1 | 0.730326 | 3 | 0 | 3 |
| PIP5KL1 | SNED1 | 0.728738 | 3 | 0 | 3 |
| PIP5KL1 | AOC2 | 0.723763 | 3 | 0 | 3 |
| PIP5KL1 | PHF1 | 0.720365 | 3 | 0 | 3 |
| PIP5KL1 | BEST2 | 0.717251 | 3 | 0 | 3 |
| PIP5KL1 | C14orf180 | 0.712132 | 3 | 0 | 3 |
| PIP5KL1 | EDA | 0.702855 | 5 | 0 | 5 |
| PIP5KL1 | RAD52 | 0.702107 | 3 | 0 | 3 |
| PIP5KL1 | CDX2 | 0.700535 | 3 | 0 | 3 |
| PIP5KL1 | LHFPL5 | 0.70023 | 4 | 0 | 3 |
| PIP5KL1 | KRTAP4-1 | 0.699549 | 3 | 0 | 3 |
| PIP5KL1 | HRC | 0.698217 | 3 | 0 | 3 |
| PIP5KL1 | CACNG8 | 0.697364 | 3 | 0 | 3 |
| PIP5KL1 | ACSM1 | 0.697126 | 4 | 0 | 4 |
For details and further investigation, click here
