| Full name: chymotrypsin like elastase 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 12q13.13 | ||
| Entrez ID: 1990 | HGNC ID: HGNC:3308 | Ensembl Gene: ENSG00000139610 | OMIM ID: 130120 |
| Drug and gene relationship at DGIdb | |||
Expression of CELA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CELA1 | 1990 | 224198_at | -0.0637 | 0.8575 | |
| GSE26886 | CELA1 | 1990 | 224198_at | 0.0495 | 0.6924 | |
| GSE45670 | CELA1 | 1990 | 224198_at | 0.0555 | 0.5667 | |
| GSE53622 | CELA1 | 1990 | 176075 | 0.0636 | 0.8130 | |
| GSE53624 | CELA1 | 1990 | 176075 | 0.0441 | 0.8099 | |
| GSE63941 | CELA1 | 1990 | 224198_at | 0.1631 | 0.2593 | |
| GSE77861 | CELA1 | 1990 | 224198_at | -0.0137 | 0.9343 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CELA1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CELA1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CELA1 | 1990 | 8 | 1 | 21 | |
| GSE20123 | CELA1 | 1990 | 8 | 1 | 21 | |
| GSE43470 | CELA1 | 1990 | 4 | 0 | 39 | |
| GSE46452 | CELA1 | 1990 | 8 | 1 | 50 | |
| GSE47630 | CELA1 | 1990 | 11 | 2 | 27 | |
| GSE54993 | CELA1 | 1990 | 0 | 5 | 65 | |
| GSE54994 | CELA1 | 1990 | 3 | 2 | 48 | |
| GSE60625 | CELA1 | 1990 | 0 | 0 | 11 | |
| GSE74703 | CELA1 | 1990 | 3 | 0 | 33 | |
| GSE74704 | CELA1 | 1990 | 5 | 1 | 14 | |
| TCGA | CELA1 | 1990 | 14 | 11 | 71 |
Total number of gains: 64; Total number of losses: 24; Total Number of normals: 400.
Somatic mutations of CELA1:
Generating mutation plots.
Highly correlated genes for CELA1:
Showing top 20/37 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CELA1 | DLGAP2-AS1 | 0.680304 | 3 | 0 | 3 |
| CELA1 | SPP2 | 0.638414 | 3 | 0 | 3 |
| CELA1 | ANKRD53 | 0.638361 | 3 | 0 | 3 |
| CELA1 | FSCN3 | 0.628889 | 4 | 0 | 3 |
| CELA1 | GRM2 | 0.617983 | 3 | 0 | 3 |
| CELA1 | HSPA1L | 0.612699 | 3 | 0 | 3 |
| CELA1 | LPA | 0.607168 | 3 | 0 | 3 |
| CELA1 | LINC01118 | 0.60142 | 4 | 0 | 4 |
| CELA1 | MYLK-AS1 | 0.596478 | 4 | 0 | 3 |
| CELA1 | DNHD1 | 0.594436 | 3 | 0 | 3 |
| CELA1 | GRPR | 0.587456 | 3 | 0 | 3 |
| CELA1 | ADAP1 | 0.587211 | 3 | 0 | 3 |
| CELA1 | FOSB | 0.586404 | 3 | 0 | 3 |
| CELA1 | MAPT-AS1 | 0.582922 | 4 | 0 | 3 |
| CELA1 | CTNND2 | 0.576261 | 3 | 0 | 3 |
| CELA1 | GNG8 | 0.574545 | 3 | 0 | 3 |
| CELA1 | FBXL6 | 0.572879 | 3 | 0 | 3 |
| CELA1 | PRSS37 | 0.570797 | 4 | 0 | 3 |
| CELA1 | OR10J1 | 0.56724 | 4 | 0 | 3 |
| CELA1 | FITM1 | 0.560364 | 4 | 0 | 3 |
For details and further investigation, click here
