| Full name: POU class 3 homeobox 1 | Alias Symbol: OCT6|SCIP | ||
| Type: protein-coding gene | Cytoband: 1p34.3 | ||
| Entrez ID: 5453 | HGNC ID: HGNC:9214 | Ensembl Gene: ENSG00000185668 | OMIM ID: 602479 |
| Drug and gene relationship at DGIdb | |||
Expression of POU3F1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | POU3F1 | 5453 | 208345_s_at | 0.4568 | 0.5444 | |
| GSE20347 | POU3F1 | 5453 | 208345_s_at | -0.1141 | 0.6250 | |
| GSE23400 | POU3F1 | 5453 | 210475_at | -0.0845 | 0.0245 | |
| GSE26886 | POU3F1 | 5453 | 208345_s_at | 0.3535 | 0.0418 | |
| GSE29001 | POU3F1 | 5453 | 210475_at | -0.0534 | 0.8073 | |
| GSE38129 | POU3F1 | 5453 | 208345_s_at | -0.1278 | 0.5728 | |
| GSE45670 | POU3F1 | 5453 | 210475_at | 0.1586 | 0.0967 | |
| GSE53622 | POU3F1 | 5453 | 47482 | 0.0414 | 0.8715 | |
| GSE53624 | POU3F1 | 5453 | 47482 | 0.0650 | 0.7066 | |
| GSE63941 | POU3F1 | 5453 | 210475_at | 0.3341 | 0.0384 | |
| GSE77861 | POU3F1 | 5453 | 210475_at | -0.2258 | 0.3404 | |
| GSE97050 | POU3F1 | 5453 | A_33_P3351052 | -0.1304 | 0.6184 | |
| SRP007169 | POU3F1 | 5453 | RNAseq | -3.8232 | 0.0000 | |
| SRP064894 | POU3F1 | 5453 | RNAseq | 0.7173 | 0.1753 | |
| SRP133303 | POU3F1 | 5453 | RNAseq | -0.1380 | 0.8061 | |
| SRP159526 | POU3F1 | 5453 | RNAseq | -1.9299 | 0.0001 | |
| SRP219564 | POU3F1 | 5453 | RNAseq | -1.2551 | 0.1197 | |
| TCGA | POU3F1 | 5453 | RNAseq | 0.9424 | 0.0074 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by POU3F1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of POU3F1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | POU3F1 | 5453 | 2 | 4 | 24 | |
| GSE20123 | POU3F1 | 5453 | 2 | 3 | 25 | |
| GSE43470 | POU3F1 | 5453 | 7 | 3 | 33 | |
| GSE46452 | POU3F1 | 5453 | 4 | 1 | 54 | |
| GSE47630 | POU3F1 | 5453 | 8 | 3 | 29 | |
| GSE54993 | POU3F1 | 5453 | 0 | 1 | 69 | |
| GSE54994 | POU3F1 | 5453 | 12 | 2 | 39 | |
| GSE60625 | POU3F1 | 5453 | 0 | 0 | 11 | |
| GSE74703 | POU3F1 | 5453 | 6 | 2 | 28 | |
| GSE74704 | POU3F1 | 5453 | 1 | 0 | 19 | |
| TCGA | POU3F1 | 5453 | 12 | 17 | 67 |
Total number of gains: 54; Total number of losses: 36; Total Number of normals: 398.
Somatic mutations of POU3F1:
Generating mutation plots.
Highly correlated genes for POU3F1:
Showing top 20/320 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| POU3F1 | DNASE1L2 | 0.710141 | 3 | 0 | 3 |
| POU3F1 | PCBP4 | 0.68553 | 4 | 0 | 4 |
| POU3F1 | KIAA0754 | 0.684114 | 3 | 0 | 3 |
| POU3F1 | NR5A1 | 0.676979 | 3 | 0 | 3 |
| POU3F1 | SIGLEC8 | 0.672507 | 4 | 0 | 4 |
| POU3F1 | TM4SF4 | 0.660706 | 3 | 0 | 3 |
| POU3F1 | IGH | 0.656758 | 3 | 0 | 3 |
| POU3F1 | AMN | 0.655195 | 5 | 0 | 4 |
| POU3F1 | IHH | 0.654254 | 4 | 0 | 3 |
| POU3F1 | GML | 0.650152 | 4 | 0 | 4 |
| POU3F1 | GRK6 | 0.648439 | 3 | 0 | 3 |
| POU3F1 | CNTD2 | 0.645594 | 5 | 0 | 4 |
| POU3F1 | FABP2 | 0.645222 | 3 | 0 | 3 |
| POU3F1 | CEMP1 | 0.644017 | 4 | 0 | 4 |
| POU3F1 | EVX1 | 0.642806 | 4 | 0 | 4 |
| POU3F1 | SSSCA1-AS1 | 0.642014 | 3 | 0 | 3 |
| POU3F1 | CHRD | 0.639854 | 3 | 0 | 3 |
| POU3F1 | TAS2R16 | 0.637852 | 3 | 0 | 3 |
| POU3F1 | HOXD11 | 0.637142 | 3 | 0 | 3 |
| POU3F1 | SNAP25 | 0.634842 | 3 | 0 | 3 |
For details and further investigation, click here
