| Full name: synaptotagmin 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19q13.33 | ||
| Entrez ID: 84258 | HGNC ID: HGNC:11511 | Ensembl Gene: ENSG00000213023 | OMIM ID: 600327 |
| Drug and gene relationship at DGIdb | |||
Expression of SYT3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SYT3 | 84258 | 223901_at | 0.0810 | 0.8087 | |
| GSE26886 | SYT3 | 84258 | 223901_at | 0.0103 | 0.9416 | |
| GSE45670 | SYT3 | 84258 | 223901_at | -0.0470 | 0.6046 | |
| GSE63941 | SYT3 | 84258 | 223901_at | 0.2981 | 0.5374 | |
| GSE77861 | SYT3 | 84258 | 223901_at | -0.3198 | 0.0206 | |
| GSE97050 | SYT3 | 84258 | A_23_P55917 | 0.1202 | 0.5200 | |
| SRP219564 | SYT3 | 84258 | RNAseq | 0.5122 | 0.4758 | |
| TCGA | SYT3 | 84258 | RNAseq | 0.8356 | 0.1287 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SYT3 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of SYT3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SYT3 | 84258 | 3 | 4 | 23 | |
| GSE20123 | SYT3 | 84258 | 3 | 3 | 24 | |
| GSE43470 | SYT3 | 84258 | 4 | 11 | 28 | |
| GSE46452 | SYT3 | 84258 | 45 | 1 | 13 | |
| GSE47630 | SYT3 | 84258 | 10 | 6 | 24 | |
| GSE54993 | SYT3 | 84258 | 17 | 4 | 49 | |
| GSE54994 | SYT3 | 84258 | 4 | 14 | 35 | |
| GSE60625 | SYT3 | 84258 | 9 | 0 | 2 | |
| GSE74703 | SYT3 | 84258 | 4 | 7 | 25 | |
| GSE74704 | SYT3 | 84258 | 3 | 1 | 16 | |
| TCGA | SYT3 | 84258 | 14 | 19 | 63 |
Total number of gains: 116; Total number of losses: 70; Total Number of normals: 302.
Somatic mutations of SYT3:
Generating mutation plots.
Highly correlated genes for SYT3:
Showing top 20/69 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SYT3 | PGC | 0.782647 | 3 | 0 | 3 |
| SYT3 | MEP1A | 0.778462 | 3 | 0 | 3 |
| SYT3 | AANAT | 0.762768 | 3 | 0 | 3 |
| SYT3 | SLC22A31 | 0.762526 | 3 | 0 | 3 |
| SYT3 | TNFRSF14 | 0.755982 | 3 | 0 | 3 |
| SYT3 | PCSK1N | 0.753913 | 3 | 0 | 3 |
| SYT3 | SPACA3 | 0.739543 | 3 | 0 | 3 |
| SYT3 | SYNGAP1 | 0.736804 | 3 | 0 | 3 |
| SYT3 | TRIM55 | 0.728155 | 3 | 0 | 3 |
| SYT3 | C7orf61 | 0.718264 | 3 | 0 | 3 |
| SYT3 | CRTAC1 | 0.710651 | 3 | 0 | 3 |
| SYT3 | TMEM239 | 0.708403 | 3 | 0 | 3 |
| SYT3 | LRFN3 | 0.70487 | 3 | 0 | 3 |
| SYT3 | SLC22A11 | 0.703694 | 3 | 0 | 3 |
| SYT3 | CSMD2 | 0.700617 | 3 | 0 | 3 |
| SYT3 | EFNA2 | 0.700477 | 3 | 0 | 3 |
| SYT3 | NRG2 | 0.697544 | 3 | 0 | 3 |
| SYT3 | DAB1 | 0.695815 | 3 | 0 | 3 |
| SYT3 | GRM4 | 0.691481 | 3 | 0 | 3 |
| SYT3 | TBC1D10C | 0.6912 | 3 | 0 | 3 |
For details and further investigation, click here
