| Full name: solute carrier family 5 member 11 | Alias Symbol: KST1|SMIT2|SGLT6 | ||
| Type: protein-coding gene | Cytoband: 16p12.1 | ||
| Entrez ID: 115584 | HGNC ID: HGNC:23091 | Ensembl Gene: ENSG00000158865 | OMIM ID: 610238 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC5A11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC5A11 | 115584 | 237254_at | 0.0386 | 0.8775 | |
| GSE26886 | SLC5A11 | 115584 | 237254_at | 0.0204 | 0.9219 | |
| GSE45670 | SLC5A11 | 115584 | 237254_at | 0.1562 | 0.1848 | |
| GSE53622 | SLC5A11 | 115584 | 34218 | 0.3090 | 0.0000 | |
| GSE53624 | SLC5A11 | 115584 | 34218 | 0.5384 | 0.0000 | |
| GSE63941 | SLC5A11 | 115584 | 237254_at | 0.1153 | 0.5360 | |
| GSE77861 | SLC5A11 | 115584 | 237254_at | -0.0482 | 0.7302 | |
| GSE97050 | SLC5A11 | 115584 | A_23_P37914 | 0.0359 | 0.8680 | |
| TCGA | SLC5A11 | 115584 | RNAseq | 1.3156 | 0.1324 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SLC5A11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC5A11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC5A11 | 115584 | 4 | 4 | 22 | |
| GSE20123 | SLC5A11 | 115584 | 4 | 3 | 23 | |
| GSE43470 | SLC5A11 | 115584 | 4 | 3 | 36 | |
| GSE46452 | SLC5A11 | 115584 | 38 | 1 | 20 | |
| GSE47630 | SLC5A11 | 115584 | 11 | 6 | 23 | |
| GSE54993 | SLC5A11 | 115584 | 3 | 5 | 62 | |
| GSE54994 | SLC5A11 | 115584 | 4 | 9 | 40 | |
| GSE60625 | SLC5A11 | 115584 | 4 | 0 | 7 | |
| GSE74703 | SLC5A11 | 115584 | 4 | 2 | 30 | |
| GSE74704 | SLC5A11 | 115584 | 2 | 1 | 17 | |
| TCGA | SLC5A11 | 115584 | 19 | 13 | 64 |
Total number of gains: 97; Total number of losses: 47; Total Number of normals: 344.
Somatic mutations of SLC5A11:
Generating mutation plots.
Highly correlated genes for SLC5A11:
Showing top 20/115 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC5A11 | CALCA | 0.786169 | 3 | 0 | 3 |
| SLC5A11 | FAM71A | 0.775194 | 3 | 0 | 3 |
| SLC5A11 | PRRG3 | 0.767319 | 3 | 0 | 3 |
| SLC5A11 | NHLRC4 | 0.761878 | 3 | 0 | 3 |
| SLC5A11 | GHRHR | 0.760481 | 3 | 0 | 3 |
| SLC5A11 | AANAT | 0.751755 | 3 | 0 | 3 |
| SLC5A11 | JAKMIP1 | 0.725592 | 3 | 0 | 3 |
| SLC5A11 | HPR | 0.723132 | 3 | 0 | 3 |
| SLC5A11 | TMEM179 | 0.718951 | 3 | 0 | 3 |
| SLC5A11 | DNAJC5B | 0.7187 | 3 | 0 | 3 |
| SLC5A11 | RASSF7 | 0.713283 | 3 | 0 | 3 |
| SLC5A11 | CLEC1B | 0.696742 | 3 | 0 | 3 |
| SLC5A11 | CIB3 | 0.695973 | 4 | 0 | 4 |
| SLC5A11 | DCD | 0.692737 | 3 | 0 | 3 |
| SLC5A11 | CACNA1G | 0.687849 | 4 | 0 | 3 |
| SLC5A11 | ADM2 | 0.685682 | 4 | 0 | 3 |
| SLC5A11 | CLDN14 | 0.68372 | 4 | 0 | 3 |
| SLC5A11 | CBLN4 | 0.681438 | 4 | 0 | 3 |
| SLC5A11 | BSND | 0.678292 | 4 | 0 | 3 |
| SLC5A11 | EGR4 | 0.674252 | 4 | 0 | 3 |
For details and further investigation, click here
