| Full name: solute carrier family 22 member 12 | Alias Symbol: OAT4L|RST|URAT1 | ||
| Type: protein-coding gene | Cytoband: 11q13.1 | ||
| Entrez ID: 116085 | HGNC ID: HGNC:17989 | Ensembl Gene: ENSG00000197891 | OMIM ID: 607096 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC22A12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC22A12 | 116085 | 237799_at | -0.0341 | 0.8977 | |
| GSE26886 | SLC22A12 | 116085 | 237799_at | 0.1462 | 0.2747 | |
| GSE45670 | SLC22A12 | 116085 | 237799_at | 0.0307 | 0.8206 | |
| GSE53622 | SLC22A12 | 116085 | 65308 | 0.0362 | 0.6675 | |
| GSE53624 | SLC22A12 | 116085 | 65308 | -0.4740 | 0.0000 | |
| GSE63941 | SLC22A12 | 116085 | 237799_at | 0.1525 | 0.4118 | |
| GSE77861 | SLC22A12 | 116085 | 237799_at | -0.0094 | 0.9568 | |
| GSE97050 | SLC22A12 | 116085 | A_33_P3316721 | 0.0455 | 0.8481 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SLC22A12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC22A12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC22A12 | 116085 | 7 | 5 | 18 | |
| GSE20123 | SLC22A12 | 116085 | 7 | 5 | 18 | |
| GSE43470 | SLC22A12 | 116085 | 1 | 3 | 39 | |
| GSE46452 | SLC22A12 | 116085 | 8 | 4 | 47 | |
| GSE47630 | SLC22A12 | 116085 | 5 | 6 | 29 | |
| GSE54993 | SLC22A12 | 116085 | 3 | 1 | 66 | |
| GSE54994 | SLC22A12 | 116085 | 6 | 5 | 42 | |
| GSE60625 | SLC22A12 | 116085 | 0 | 3 | 8 | |
| GSE74703 | SLC22A12 | 116085 | 1 | 1 | 34 | |
| GSE74704 | SLC22A12 | 116085 | 5 | 3 | 12 | |
| TCGA | SLC22A12 | 116085 | 21 | 9 | 66 |
Total number of gains: 64; Total number of losses: 45; Total Number of normals: 379.
Somatic mutations of SLC22A12:
Generating mutation plots.
Highly correlated genes for SLC22A12:
Showing top 20/527 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC22A12 | YY2 | 0.893285 | 3 | 0 | 3 |
| SLC22A12 | PAX6 | 0.848306 | 3 | 0 | 3 |
| SLC22A12 | OTOG | 0.842485 | 3 | 0 | 3 |
| SLC22A12 | KRTAP4-8 | 0.841693 | 4 | 0 | 4 |
| SLC22A12 | PRSS38 | 0.840052 | 3 | 0 | 3 |
| SLC22A12 | TSSK3 | 0.835208 | 4 | 0 | 4 |
| SLC22A12 | TTC21A | 0.832839 | 3 | 0 | 3 |
| SLC22A12 | PRG3 | 0.828178 | 4 | 0 | 4 |
| SLC22A12 | AQP8 | 0.820399 | 3 | 0 | 3 |
| SLC22A12 | DCDC1 | 0.819138 | 3 | 0 | 3 |
| SLC22A12 | ST8SIA1 | 0.814884 | 3 | 0 | 3 |
| SLC22A12 | ZNF236 | 0.804504 | 3 | 0 | 3 |
| SLC22A12 | OR2B11 | 0.804359 | 3 | 0 | 3 |
| SLC22A12 | SALL3 | 0.803686 | 3 | 0 | 3 |
| SLC22A12 | OR2T27 | 0.803239 | 3 | 0 | 3 |
| SLC22A12 | KRTAP6-1 | 0.80102 | 3 | 0 | 3 |
| SLC22A12 | BSX | 0.797945 | 3 | 0 | 3 |
| SLC22A12 | STRC | 0.796608 | 3 | 0 | 3 |
| SLC22A12 | AANAT | 0.794144 | 3 | 0 | 3 |
| SLC22A12 | OR13G1 | 0.794099 | 3 | 0 | 3 |
For details and further investigation, click here
