| Full name: ADAMTS like 4 | Alias Symbol: DKFZP434K1772 | ||
| Type: protein-coding gene | Cytoband: 1q21.2 | ||
| Entrez ID: 54507 | HGNC ID: HGNC:19706 | Ensembl Gene: ENSG00000143382 | OMIM ID: 610113 |
| Drug and gene relationship at DGIdb | |||
Expression of ADAMTSL4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ADAMTSL4 | 54507 | 226071_at | -1.4693 | 0.0286 | |
| GSE20347 | ADAMTSL4 | 54507 | 220578_at | -0.4182 | 0.0012 | |
| GSE23400 | ADAMTSL4 | 54507 | 220578_at | -0.5079 | 0.0000 | |
| GSE26886 | ADAMTSL4 | 54507 | 226071_at | -1.6660 | 0.0000 | |
| GSE29001 | ADAMTSL4 | 54507 | 220578_at | -0.7123 | 0.0143 | |
| GSE38129 | ADAMTSL4 | 54507 | 220578_at | -0.5454 | 0.0005 | |
| GSE45670 | ADAMTSL4 | 54507 | 226071_at | -0.3497 | 0.1174 | |
| GSE53622 | ADAMTSL4 | 54507 | 134183 | -1.4925 | 0.0000 | |
| GSE53624 | ADAMTSL4 | 54507 | 162479 | -1.4097 | 0.0000 | |
| GSE63941 | ADAMTSL4 | 54507 | 226071_at | -0.0020 | 0.9982 | |
| GSE77861 | ADAMTSL4 | 54507 | 226071_at | -0.7849 | 0.0439 | |
| GSE97050 | ADAMTSL4 | 54507 | A_33_P3299220 | -0.2173 | 0.4926 | |
| SRP007169 | ADAMTSL4 | 54507 | RNAseq | -2.6402 | 0.0005 | |
| SRP008496 | ADAMTSL4 | 54507 | RNAseq | -2.9866 | 0.0000 | |
| SRP064894 | ADAMTSL4 | 54507 | RNAseq | -1.1999 | 0.0005 | |
| SRP133303 | ADAMTSL4 | 54507 | RNAseq | -1.3296 | 0.0000 | |
| SRP159526 | ADAMTSL4 | 54507 | RNAseq | -2.5612 | 0.0000 | |
| SRP193095 | ADAMTSL4 | 54507 | RNAseq | -0.6360 | 0.0155 | |
| SRP219564 | ADAMTSL4 | 54507 | RNAseq | -1.4052 | 0.0001 | |
| TCGA | ADAMTSL4 | 54507 | RNAseq | -0.4544 | 0.0029 |
Upregulated datasets: 0; Downregulated datasets: 10.
Survival by ADAMTSL4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ADAMTSL4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ADAMTSL4 | 54507 | 15 | 0 | 15 | |
| GSE20123 | ADAMTSL4 | 54507 | 15 | 0 | 15 | |
| GSE43470 | ADAMTSL4 | 54507 | 6 | 1 | 36 | |
| GSE46452 | ADAMTSL4 | 54507 | 2 | 1 | 56 | |
| GSE47630 | ADAMTSL4 | 54507 | 14 | 0 | 26 | |
| GSE54993 | ADAMTSL4 | 54507 | 0 | 3 | 67 | |
| GSE54994 | ADAMTSL4 | 54507 | 15 | 0 | 38 | |
| GSE60625 | ADAMTSL4 | 54507 | 0 | 0 | 11 | |
| GSE74703 | ADAMTSL4 | 54507 | 6 | 1 | 29 | |
| GSE74704 | ADAMTSL4 | 54507 | 7 | 0 | 13 | |
| TCGA | ADAMTSL4 | 54507 | 38 | 2 | 56 |
Total number of gains: 118; Total number of losses: 8; Total Number of normals: 362.
Somatic mutations of ADAMTSL4:
Generating mutation plots.
Highly correlated genes for ADAMTSL4:
Showing top 20/948 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ADAMTSL4 | BTBD19 | 0.847828 | 3 | 0 | 3 |
| ADAMTSL4 | BTNL9 | 0.828801 | 3 | 0 | 3 |
| ADAMTSL4 | FAM163B | 0.823984 | 3 | 0 | 3 |
| ADAMTSL4 | OR10G8 | 0.82174 | 3 | 0 | 3 |
| ADAMTSL4 | CYSRT1 | 0.801044 | 6 | 0 | 6 |
| ADAMTSL4 | MFSD2B | 0.799405 | 3 | 0 | 3 |
| ADAMTSL4 | KRTAP20-1 | 0.795718 | 3 | 0 | 3 |
| ADAMTSL4 | OR2Z1 | 0.787711 | 3 | 0 | 3 |
| ADAMTSL4 | BARHL2 | 0.782683 | 3 | 0 | 3 |
| ADAMTSL4 | TEN1 | 0.760991 | 3 | 0 | 3 |
| ADAMTSL4 | MUC22 | 0.758866 | 3 | 0 | 3 |
| ADAMTSL4 | SLC35C1 | 0.750467 | 11 | 0 | 11 |
| ADAMTSL4 | LYNX1 | 0.749806 | 7 | 0 | 7 |
| ADAMTSL4 | ANKRD35 | 0.748629 | 6 | 0 | 6 |
| ADAMTSL4 | CRYBB3 | 0.74739 | 3 | 0 | 3 |
| ADAMTSL4 | TRNP1 | 0.744809 | 6 | 0 | 6 |
| ADAMTSL4 | GPR62 | 0.737724 | 3 | 0 | 3 |
| ADAMTSL4 | VSIG10L | 0.737002 | 7 | 0 | 6 |
| ADAMTSL4 | EPS8L2 | 0.736838 | 11 | 0 | 11 |
| ADAMTSL4 | SLC25A48 | 0.732401 | 3 | 0 | 3 |
For details and further investigation, click here
