| Full name: mucin 22 | Alias Symbol: PBMUCL1 | ||
| Type: protein-coding gene | Cytoband: 6p21.33 | ||
| Entrez ID: 100507679 | HGNC ID: HGNC:39755 | Ensembl Gene: ENSG00000261272 | OMIM ID: 613917 |
| Drug and gene relationship at DGIdb | |||
Expression of MUC22:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | MUC22 | 100507679 | 167230 | -2.1902 | 0.0000 | |
| GSE53624 | MUC22 | 100507679 | 167230 | -2.4889 | 0.0000 | |
| GSE97050 | MUC22 | 100507679 | A_33_P3214914 | -0.9588 | 0.3275 | |
| SRP007169 | MUC22 | 100507679 | RNAseq | -9.2559 | 0.0000 | |
| SRP008496 | MUC22 | 100507679 | RNAseq | -8.6912 | 0.0000 | |
| SRP064894 | MUC22 | 100507679 | RNAseq | -5.2225 | 0.0000 | |
| SRP133303 | MUC22 | 100507679 | RNAseq | -6.2331 | 0.0000 | |
| SRP159526 | MUC22 | 100507679 | RNAseq | -6.9284 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by MUC22 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of MUC22:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MUC22 | 100507679 | 5 | 1 | 24 | |
| GSE20123 | MUC22 | 100507679 | 5 | 1 | 24 | |
| GSE43470 | MUC22 | 100507679 | 5 | 1 | 37 | |
| GSE46452 | MUC22 | 100507679 | 1 | 10 | 48 | |
| GSE47630 | MUC22 | 100507679 | 7 | 3 | 30 | |
| GSE54993 | MUC22 | 100507679 | 2 | 1 | 67 | |
| GSE54994 | MUC22 | 100507679 | 11 | 4 | 38 | |
| GSE60625 | MUC22 | 100507679 | 0 | 1 | 10 | |
| GSE74703 | MUC22 | 100507679 | 5 | 0 | 31 | |
| GSE74704 | MUC22 | 100507679 | 2 | 0 | 18 | |
| TCGA | MUC22 | 100507679 | 17 | 16 | 63 |
Total number of gains: 60; Total number of losses: 38; Total Number of normals: 390.
Somatic mutations of MUC22:
Generating mutation plots.
Highly correlated genes for MUC22:
Showing top 20/329 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MUC22 | ACSM1 | 0.894275 | 3 | 0 | 3 |
| MUC22 | EPS8L2 | 0.868084 | 3 | 0 | 3 |
| MUC22 | FAM163B | 0.857937 | 3 | 0 | 3 |
| MUC22 | PTK6 | 0.856992 | 3 | 0 | 3 |
| MUC22 | PRSS27 | 0.850184 | 3 | 0 | 3 |
| MUC22 | PMM1 | 0.848391 | 3 | 0 | 3 |
| MUC22 | SPINK7 | 0.848199 | 3 | 0 | 3 |
| MUC22 | APOA1 | 0.846379 | 3 | 0 | 3 |
| MUC22 | MFSD2B | 0.845262 | 3 | 0 | 3 |
| MUC22 | ARID5A | 0.831672 | 3 | 0 | 3 |
| MUC22 | HES5 | 0.829179 | 3 | 0 | 3 |
| MUC22 | KRT32 | 0.828756 | 3 | 0 | 3 |
| MUC22 | NCCRP1 | 0.822798 | 3 | 0 | 3 |
| MUC22 | NCR1 | 0.820985 | 3 | 0 | 3 |
| MUC22 | SLURP1 | 0.82096 | 3 | 0 | 3 |
| MUC22 | ACOT8 | 0.820012 | 3 | 0 | 3 |
| MUC22 | FBXO34 | 0.819797 | 3 | 0 | 3 |
| MUC22 | PLEKHN1 | 0.819293 | 3 | 0 | 3 |
| MUC22 | GGT6 | 0.818502 | 3 | 0 | 3 |
| MUC22 | RAET1E | 0.818034 | 3 | 0 | 3 |
For details and further investigation, click here
