| Full name: EPS8 like 2 | Alias Symbol: FLJ21935|FLJ22171|MGC3088 | ||
| Type: protein-coding gene | Cytoband: 11p15.5 | ||
| Entrez ID: 64787 | HGNC ID: HGNC:21296 | Ensembl Gene: ENSG00000177106 | OMIM ID: 614988 |
| Drug and gene relationship at DGIdb | |||
Expression of EPS8L2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EPS8L2 | 64787 | 218180_s_at | -1.5197 | 0.0900 | |
| GSE20347 | EPS8L2 | 64787 | 218180_s_at | -2.2769 | 0.0000 | |
| GSE23400 | EPS8L2 | 64787 | 218180_s_at | -1.7882 | 0.0000 | |
| GSE26886 | EPS8L2 | 64787 | 218180_s_at | -2.0261 | 0.0000 | |
| GSE29001 | EPS8L2 | 64787 | 218180_s_at | -2.1534 | 0.0000 | |
| GSE38129 | EPS8L2 | 64787 | 218180_s_at | -1.6222 | 0.0000 | |
| GSE45670 | EPS8L2 | 64787 | 218180_s_at | -0.9570 | 0.0076 | |
| GSE53622 | EPS8L2 | 64787 | 38029 | -1.9854 | 0.0000 | |
| GSE53624 | EPS8L2 | 64787 | 38029 | -2.4888 | 0.0000 | |
| GSE63941 | EPS8L2 | 64787 | 218180_s_at | -0.2382 | 0.8083 | |
| GSE77861 | EPS8L2 | 64787 | 218180_s_at | -1.6088 | 0.0015 | |
| GSE97050 | EPS8L2 | 64787 | A_23_P147822 | -0.4531 | 0.3673 | |
| SRP007169 | EPS8L2 | 64787 | RNAseq | -2.8539 | 0.0000 | |
| SRP008496 | EPS8L2 | 64787 | RNAseq | -2.5651 | 0.0000 | |
| SRP064894 | EPS8L2 | 64787 | RNAseq | -2.4760 | 0.0000 | |
| SRP133303 | EPS8L2 | 64787 | RNAseq | -2.4295 | 0.0000 | |
| SRP159526 | EPS8L2 | 64787 | RNAseq | -2.7060 | 0.0000 | |
| SRP193095 | EPS8L2 | 64787 | RNAseq | -2.1182 | 0.0000 | |
| SRP219564 | EPS8L2 | 64787 | RNAseq | -2.0419 | 0.0156 | |
| TCGA | EPS8L2 | 64787 | RNAseq | -0.0600 | 0.5397 |
Upregulated datasets: 0; Downregulated datasets: 15.
Survival by EPS8L2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EPS8L2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EPS8L2 | 64787 | 1 | 11 | 18 | |
| GSE20123 | EPS8L2 | 64787 | 1 | 12 | 17 | |
| GSE43470 | EPS8L2 | 64787 | 1 | 10 | 32 | |
| GSE46452 | EPS8L2 | 64787 | 7 | 8 | 44 | |
| GSE47630 | EPS8L2 | 64787 | 4 | 12 | 24 | |
| GSE54993 | EPS8L2 | 64787 | 3 | 1 | 66 | |
| GSE54994 | EPS8L2 | 64787 | 1 | 12 | 40 | |
| GSE60625 | EPS8L2 | 64787 | 0 | 0 | 11 | |
| GSE74703 | EPS8L2 | 64787 | 1 | 8 | 27 | |
| GSE74704 | EPS8L2 | 64787 | 0 | 8 | 12 | |
| TCGA | EPS8L2 | 64787 | 8 | 38 | 50 |
Total number of gains: 27; Total number of losses: 120; Total Number of normals: 341.
Somatic mutations of EPS8L2:
Generating mutation plots.
Highly correlated genes for EPS8L2:
Showing top 20/1102 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EPS8L2 | FAM163B | 0.920425 | 3 | 0 | 3 |
| EPS8L2 | NCCRP1 | 0.90832 | 3 | 0 | 3 |
| EPS8L2 | TRIP10 | 0.906296 | 10 | 0 | 10 |
| EPS8L2 | PRSS27 | 0.904695 | 7 | 0 | 7 |
| EPS8L2 | SCNN1B | 0.89449 | 11 | 0 | 11 |
| EPS8L2 | SLURP1 | 0.884172 | 11 | 0 | 11 |
| EPS8L2 | EPS8L1 | 0.882298 | 11 | 0 | 11 |
| EPS8L2 | PADI1 | 0.877568 | 8 | 0 | 8 |
| EPS8L2 | SFTA2 | 0.876922 | 4 | 0 | 4 |
| EPS8L2 | ENDOU | 0.873641 | 10 | 0 | 10 |
| EPS8L2 | ECM1 | 0.872875 | 11 | 0 | 11 |
| EPS8L2 | PTK6 | 0.871317 | 12 | 0 | 11 |
| EPS8L2 | VSIG10L | 0.869523 | 7 | 0 | 7 |
| EPS8L2 | SLC35C1 | 0.86865 | 11 | 0 | 11 |
| EPS8L2 | CAPN14 | 0.868285 | 6 | 0 | 6 |
| EPS8L2 | KRTAP20-1 | 0.868209 | 3 | 0 | 3 |
| EPS8L2 | MUC22 | 0.868084 | 3 | 0 | 3 |
| EPS8L2 | C5orf66-AS1 | 0.862502 | 6 | 0 | 6 |
| EPS8L2 | SPINK7 | 0.861 | 7 | 0 | 7 |
| EPS8L2 | S100A14 | 0.860565 | 11 | 0 | 11 |
For details and further investigation, click here
