| Full name: TMF1 regulated nuclear protein 1 | Alias Symbol: TRNP | ||
| Type: protein-coding gene | Cytoband: 1p36.11 | ||
| Entrez ID: 388610 | HGNC ID: HGNC:34348 | Ensembl Gene: ENSG00000253368 | OMIM ID: 616824 |
| Drug and gene relationship at DGIdb | |||
Expression of TRNP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRNP1 | 388610 | 227862_at | -2.3579 | 0.0148 | |
| GSE26886 | TRNP1 | 388610 | 227862_at | -3.4720 | 0.0000 | |
| GSE45670 | TRNP1 | 388610 | 227862_at | -0.5961 | 0.4394 | |
| GSE53622 | TRNP1 | 388610 | 59955 | -2.7240 | 0.0000 | |
| GSE53624 | TRNP1 | 388610 | 59955 | -3.0057 | 0.0000 | |
| GSE63941 | TRNP1 | 388610 | 227862_at | -1.8096 | 0.0335 | |
| GSE77861 | TRNP1 | 388610 | 227862_at | -2.8426 | 0.0009 | |
| GSE97050 | TRNP1 | 388610 | A_24_P734953 | -1.3069 | 0.0700 | |
| SRP007169 | TRNP1 | 388610 | RNAseq | -4.7109 | 0.0000 | |
| SRP008496 | TRNP1 | 388610 | RNAseq | -5.2817 | 0.0000 | |
| SRP064894 | TRNP1 | 388610 | RNAseq | -3.2631 | 0.0000 | |
| SRP133303 | TRNP1 | 388610 | RNAseq | -2.7784 | 0.0000 | |
| SRP159526 | TRNP1 | 388610 | RNAseq | -3.6656 | 0.0000 | |
| SRP193095 | TRNP1 | 388610 | RNAseq | -2.2663 | 0.0000 | |
| SRP219564 | TRNP1 | 388610 | RNAseq | -3.8056 | 0.0000 | |
| TCGA | TRNP1 | 388610 | RNAseq | -0.9017 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 13.
Survival by TRNP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRNP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRNP1 | 388610 | 0 | 6 | 24 | |
| GSE20123 | TRNP1 | 388610 | 0 | 5 | 25 | |
| GSE43470 | TRNP1 | 388610 | 2 | 6 | 35 | |
| GSE46452 | TRNP1 | 388610 | 5 | 1 | 53 | |
| GSE47630 | TRNP1 | 388610 | 8 | 3 | 29 | |
| GSE54993 | TRNP1 | 388610 | 2 | 1 | 67 | |
| GSE54994 | TRNP1 | 388610 | 10 | 4 | 39 | |
| GSE60625 | TRNP1 | 388610 | 0 | 0 | 11 | |
| GSE74703 | TRNP1 | 388610 | 1 | 4 | 31 | |
| GSE74704 | TRNP1 | 388610 | 0 | 0 | 20 | |
| TCGA | TRNP1 | 388610 | 10 | 24 | 62 |
Total number of gains: 38; Total number of losses: 54; Total Number of normals: 396.
Somatic mutations of TRNP1:
Generating mutation plots.
Highly correlated genes for TRNP1:
Showing top 20/1287 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRNP1 | MYZAP | 0.849292 | 3 | 0 | 3 |
| TRNP1 | EPS8L2 | 0.837288 | 6 | 0 | 6 |
| TRNP1 | UBL3 | 0.828059 | 7 | 0 | 7 |
| TRNP1 | ANXA9 | 0.824775 | 7 | 0 | 7 |
| TRNP1 | KRT78 | 0.821568 | 8 | 0 | 8 |
| TRNP1 | SH3BGRL2 | 0.815278 | 7 | 0 | 7 |
| TRNP1 | FAM214A | 0.81387 | 6 | 0 | 6 |
| TRNP1 | ARHGEF10L | 0.807704 | 7 | 0 | 7 |
| TRNP1 | PSCA | 0.80753 | 4 | 0 | 4 |
| TRNP1 | KIAA1211L | 0.804667 | 6 | 0 | 6 |
| TRNP1 | CAST | 0.799503 | 7 | 0 | 7 |
| TRNP1 | VSIG10L | 0.797244 | 7 | 0 | 7 |
| TRNP1 | LYNX1 | 0.796776 | 8 | 0 | 8 |
| TRNP1 | ATP6V0A4 | 0.794363 | 6 | 0 | 6 |
| TRNP1 | PPP1R3C | 0.792824 | 9 | 0 | 9 |
| TRNP1 | SNORA68 | 0.790375 | 4 | 0 | 4 |
| TRNP1 | RAB5A | 0.79009 | 6 | 0 | 6 |
| TRNP1 | MUC1 | 0.79003 | 6 | 0 | 6 |
| TRNP1 | MGLL | 0.787425 | 8 | 0 | 8 |
| TRNP1 | CXCR2 | 0.786798 | 7 | 0 | 7 |
For details and further investigation, click here
