| Full name: aarF domain containing kinase 2 | Alias Symbol: MGC20727 | ||
| Type: protein-coding gene | Cytoband: 7q34 | ||
| Entrez ID: 90956 | HGNC ID: HGNC:19039 | Ensembl Gene: ENSG00000133597 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ADCK2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ADCK2 | 90956 | 44120_at | -0.2271 | 0.6948 | |
| GSE20347 | ADCK2 | 90956 | 44120_at | -0.2051 | 0.1163 | |
| GSE23400 | ADCK2 | 90956 | 44120_at | -0.0647 | 0.1328 | |
| GSE26886 | ADCK2 | 90956 | 44120_at | -0.0214 | 0.9377 | |
| GSE29001 | ADCK2 | 90956 | 44120_at | -0.0272 | 0.9020 | |
| GSE38129 | ADCK2 | 90956 | 44120_at | -0.0577 | 0.6518 | |
| GSE45670 | ADCK2 | 90956 | 44120_at | 0.0028 | 0.9892 | |
| GSE53622 | ADCK2 | 90956 | 95759 | -0.0254 | 0.7979 | |
| GSE53624 | ADCK2 | 90956 | 95759 | 0.0359 | 0.6915 | |
| GSE63941 | ADCK2 | 90956 | 44120_at | 0.9568 | 0.0201 | |
| GSE77861 | ADCK2 | 90956 | 44120_at | 0.0266 | 0.9107 | |
| GSE97050 | ADCK2 | 90956 | A_24_P291978 | 0.1613 | 0.4850 | |
| SRP007169 | ADCK2 | 90956 | RNAseq | -0.7352 | 0.0823 | |
| SRP008496 | ADCK2 | 90956 | RNAseq | -0.3449 | 0.1846 | |
| SRP064894 | ADCK2 | 90956 | RNAseq | 0.4879 | 0.0947 | |
| SRP133303 | ADCK2 | 90956 | RNAseq | 0.0335 | 0.8551 | |
| SRP159526 | ADCK2 | 90956 | RNAseq | 0.0207 | 0.9518 | |
| SRP193095 | ADCK2 | 90956 | RNAseq | -0.1841 | 0.1166 | |
| SRP219564 | ADCK2 | 90956 | RNAseq | -0.1969 | 0.4942 | |
| TCGA | ADCK2 | 90956 | RNAseq | 0.0696 | 0.2928 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ADCK2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ADCK2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ADCK2 | 90956 | 5 | 2 | 23 | |
| GSE20123 | ADCK2 | 90956 | 5 | 2 | 23 | |
| GSE43470 | ADCK2 | 90956 | 2 | 4 | 37 | |
| GSE46452 | ADCK2 | 90956 | 7 | 2 | 50 | |
| GSE47630 | ADCK2 | 90956 | 7 | 4 | 29 | |
| GSE54993 | ADCK2 | 90956 | 3 | 5 | 62 | |
| GSE54994 | ADCK2 | 90956 | 5 | 8 | 40 | |
| GSE60625 | ADCK2 | 90956 | 0 | 0 | 11 | |
| GSE74703 | ADCK2 | 90956 | 2 | 4 | 30 | |
| GSE74704 | ADCK2 | 90956 | 1 | 2 | 17 | |
| TCGA | ADCK2 | 90956 | 28 | 22 | 46 |
Total number of gains: 65; Total number of losses: 55; Total Number of normals: 368.
Somatic mutations of ADCK2:
Generating mutation plots.
Highly correlated genes for ADCK2:
Showing top 20/263 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ADCK2 | ZBTB25 | 0.777909 | 3 | 0 | 3 |
| ADCK2 | LANCL1 | 0.774705 | 3 | 0 | 3 |
| ADCK2 | DUS4L | 0.762679 | 3 | 0 | 3 |
| ADCK2 | ZBED5 | 0.751824 | 3 | 0 | 3 |
| ADCK2 | TMEM17 | 0.748919 | 3 | 0 | 3 |
| ADCK2 | VPS36 | 0.745281 | 3 | 0 | 3 |
| ADCK2 | COG1 | 0.740477 | 3 | 0 | 3 |
| ADCK2 | GMCL1 | 0.73184 | 3 | 0 | 3 |
| ADCK2 | RPS21 | 0.720434 | 3 | 0 | 3 |
| ADCK2 | NXF1 | 0.720327 | 3 | 0 | 3 |
| ADCK2 | CA5B | 0.720306 | 3 | 0 | 3 |
| ADCK2 | ZSCAN20 | 0.717822 | 3 | 0 | 3 |
| ADCK2 | OFD1 | 0.716922 | 3 | 0 | 3 |
| ADCK2 | PTPN9 | 0.716397 | 3 | 0 | 3 |
| ADCK2 | DUT | 0.716123 | 3 | 0 | 3 |
| ADCK2 | ZNF570 | 0.713223 | 3 | 0 | 3 |
| ADCK2 | ATRIP | 0.704666 | 3 | 0 | 3 |
| ADCK2 | ZNF764 | 0.695217 | 3 | 0 | 3 |
| ADCK2 | GATA1 | 0.692586 | 3 | 0 | 3 |
| ADCK2 | EXOC4 | 0.688227 | 5 | 0 | 3 |
For details and further investigation, click here
