GMCL1

 

Full name: germ cell-less 1, spermatogenesis associated Alias Symbol: FLJ13057|BTBD13|GCL1|SPATA29
Type: protein-coding gene Cytoband: 2p13.3
Entrez ID: 64395 HGNC ID: HGNC:23843 Ensembl Gene: ENSG00000087338 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of GMCL1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 GMCL1 64395 239355_at 0.3071 0.6235
GSE26886 GMCL1 64395 239355_at 0.9560 0.0001
GSE45670 GMCL1 64395 239355_at 0.1592 0.2518
GSE53622 GMCL1 64395 25505 0.3136 0.0000
GSE53624 GMCL1 64395 25505 0.2116 0.0101
GSE63941 GMCL1 64395 239355_at -0.2141 0.6050
GSE77861 GMCL1 64395 239355_at 0.2431 0.4136
GSE97050 GMCL1 64395 A_23_P28375 0.2451 0.3704
SRP007169 GMCL1 64395 RNAseq 0.9365 0.0380
SRP008496 GMCL1 64395 RNAseq 1.1930 0.0000
SRP064894 GMCL1 64395 RNAseq 0.0984 0.6826
SRP133303 GMCL1 64395 RNAseq 0.5060 0.0084
SRP159526 GMCL1 64395 RNAseq 0.5360 0.0051
SRP193095 GMCL1 64395 RNAseq -0.0120 0.9183
SRP219564 GMCL1 64395 RNAseq 0.0892 0.7659
TCGA GMCL1 64395 RNAseq 0.0692 0.2652

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by GMCL1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of GMCL1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 GMCL1 64395 11 0 19
GSE20123 GMCL1 64395 11 0 19
GSE43470 GMCL1 64395 3 0 40
GSE46452 GMCL1 64395 2 3 54
GSE47630 GMCL1 64395 7 0 33
GSE54993 GMCL1 64395 0 6 64
GSE54994 GMCL1 64395 12 0 41
GSE60625 GMCL1 64395 0 3 8
GSE74703 GMCL1 64395 3 0 33
GSE74704 GMCL1 64395 9 0 11
TCGA GMCL1 64395 37 2 57

Total number of gains: 95; Total number of losses: 14; Total Number of normals: 379.  

 

Somatic mutations of GMCL1:

 

Generating mutation plots.

 

Highly correlated genes for GMCL1:

 

Showing top 20/798 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
GMCL1LARP40.814839303
GMCL1IREB20.81278303
GMCL1ZFPL10.808019303
GMCL1TAS2R190.804549303
GMCL1SDHB0.804137303
GMCL1AGK0.790837303
GMCL1MPG0.784103303
GMCL1GSPT10.777463303
GMCL1DIP2B0.776607303
GMCL1HMGN40.77144303
GMCL1PWWP2A0.766979303
GMCL1TP53I130.766501303
GMCL1MYO5A0.766142303
GMCL1SLC25A240.756756303
GMCL1PTRHD10.752308303
GMCL1HSD17B10.750901303
GMCL1LRRC280.749527303
GMCL1WDR810.746929303
GMCL1TBX10.745145303
GMCL1MARK10.745025303

For details and further investigation, click here