| Full name: component of oligomeric golgi complex 1 | Alias Symbol: KIAA1381 | ||
| Type: protein-coding gene | Cytoband: 17q25.1 | ||
| Entrez ID: 9382 | HGNC ID: HGNC:6545 | Ensembl Gene: ENSG00000166685 | OMIM ID: 606973 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of COG1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COG1 | 9382 | 227784_s_at | -0.2548 | 0.5779 | |
| GSE26886 | COG1 | 9382 | 227784_s_at | 0.3227 | 0.1015 | |
| GSE45670 | COG1 | 9382 | 227784_s_at | -0.3907 | 0.0058 | |
| GSE63941 | COG1 | 9382 | 227784_s_at | 0.0261 | 0.9462 | |
| GSE77861 | COG1 | 9382 | 227784_s_at | 0.0491 | 0.9058 | |
| GSE97050 | COG1 | 9382 | A_33_P3372580 | -0.1411 | 0.4728 | |
| SRP007169 | COG1 | 9382 | RNAseq | -0.1957 | 0.5597 | |
| SRP008496 | COG1 | 9382 | RNAseq | -0.1966 | 0.2908 | |
| SRP064894 | COG1 | 9382 | RNAseq | 0.2446 | 0.0491 | |
| SRP133303 | COG1 | 9382 | RNAseq | 0.0823 | 0.6622 | |
| SRP159526 | COG1 | 9382 | RNAseq | 0.1125 | 0.6686 | |
| SRP193095 | COG1 | 9382 | RNAseq | 0.0051 | 0.9655 | |
| SRP219564 | COG1 | 9382 | RNAseq | -0.1017 | 0.7553 | |
| TCGA | COG1 | 9382 | RNAseq | -0.1714 | 0.0004 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by COG1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of COG1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COG1 | 9382 | 3 | 2 | 25 | |
| GSE20123 | COG1 | 9382 | 3 | 2 | 25 | |
| GSE43470 | COG1 | 9382 | 6 | 3 | 34 | |
| GSE46452 | COG1 | 9382 | 33 | 0 | 26 | |
| GSE47630 | COG1 | 9382 | 8 | 1 | 31 | |
| GSE54993 | COG1 | 9382 | 2 | 5 | 63 | |
| GSE54994 | COG1 | 9382 | 10 | 4 | 39 | |
| GSE60625 | COG1 | 9382 | 6 | 0 | 5 | |
| GSE74703 | COG1 | 9382 | 6 | 1 | 29 | |
| GSE74704 | COG1 | 9382 | 3 | 2 | 15 | |
| TCGA | COG1 | 9382 | 32 | 10 | 54 |
Total number of gains: 112; Total number of losses: 30; Total Number of normals: 346.
Somatic mutations of COG1:
Generating mutation plots.
Highly correlated genes for COG1:
Showing top 20/163 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COG1 | LRRC47 | 0.817395 | 3 | 0 | 3 |
| COG1 | C1orf50 | 0.805717 | 3 | 0 | 3 |
| COG1 | CASKIN2 | 0.797278 | 3 | 0 | 3 |
| COG1 | MYSM1 | 0.791508 | 3 | 0 | 3 |
| COG1 | TMCC1 | 0.790529 | 3 | 0 | 3 |
| COG1 | REPS1 | 0.787625 | 3 | 0 | 3 |
| COG1 | TLE4 | 0.786484 | 3 | 0 | 3 |
| COG1 | CREBBP | 0.783789 | 3 | 0 | 3 |
| COG1 | MYO1D | 0.766646 | 3 | 0 | 3 |
| COG1 | TMEM205 | 0.762735 | 3 | 0 | 3 |
| COG1 | B9D2 | 0.762616 | 3 | 0 | 3 |
| COG1 | STUB1 | 0.761352 | 3 | 0 | 3 |
| COG1 | PDK2 | 0.758802 | 3 | 0 | 3 |
| COG1 | GOLGB1 | 0.74508 | 3 | 0 | 3 |
| COG1 | HECTD3 | 0.741442 | 3 | 0 | 3 |
| COG1 | ADCK2 | 0.740477 | 3 | 0 | 3 |
| COG1 | TNRC6A | 0.737692 | 3 | 0 | 3 |
| COG1 | CTCF | 0.735997 | 3 | 0 | 3 |
| COG1 | GDE1 | 0.735509 | 3 | 0 | 3 |
| COG1 | ZNF213 | 0.73461 | 3 | 0 | 3 |
For details and further investigation, click here
